Organic Geochemistry Research Lab
(OGRL)
(OGRL)
Algal toxins are a group of toxic compounds produced by a range of photosynthetic freshwater and marine plankton. These toxins have the ability to cause sickness in animals and humans and in severe cases lead to death. OGRL has the ability to evaluate and conduct occurrence, fate, transport, effects, and treatability studies methods.
Below are multimedia items associated with this project.
Below are publications associated with this project.
Land use patterns, ecoregion, and microcystin relationships in U.S. lakes and reservoirs: a preliminary evaluation
A statistically significant association was found between the concentration of total microcystin, a common class of cyanotoxins, in surface waters of lakes and reservoirs in the continental U.S. with watershed land use using data from 1156 water bodies sampled between May and October 2007 as part of the USEPA National Lakes Assessment. Nearly two thirds (65.8%) of the samples with...
Authors
John R. Beaver, Erin E. Manis, Keith Loftin, Jennifer L. Graham, Amina Pollard, Richard S. Mitchell
A review on cylindrospermopsin: the global occurrence, detection, toxicity and degradation of a potent cyanotoxin
Cylindrospermopsin is an important cyanobacterial toxin found in water bodies worldwide. The ever-increasing and global occurrence of massive and prolonged blooms of cylindrospermopsin-producing cyanobacteria poses a potential threat to both human and ecosystem health. Its toxicity is associated with metabolic activation and may involve mechanisms that adversely affect a wide variety of...
Authors
Armah A. de la Cruz, Anastasia Hiskia, Triantafyllos Kaloudis, Neil Chernoff, Donna Hill, Maria G. Antoniou, Xuexiang He, Keith Loftin, Kevin O'Shea, Cen Zhao, Miguel Pelaez, Changseok Han, Trevor J. Lynch, Dionysios D. Dionysiou
Relations between DNA- and RNA-based molecular methods for cyanobacteria and microcystin concentration at Maumee Bay State Park Lakeside Beach, Oregon, Ohio, 2012
Water samples were collected from Maumee Bay State Park Lakeside Beach, Oregon, Ohio, during the 2012 recreational season and analyzed for selected cyanobacteria gene sequences by DNA-based quantitative polymerase chain reaction (qPCR) and RNA-based quantitative reverse-transcription polymerase chain reaction (qRT-PCR). Results from the four DNA assays (for quantifying total...
Authors
Erin Stelzer, Keith Loftin, Pamela Struffolino
Cyanotoxin mixtures and taste-and-odor compounds in cyanobacterial blooms from the midwestern united states
The mixtures of toxins and taste-and-odor compounds present during cyanobacterial blooms are not well characterized and of particular concern when evaluating potential human health risks. Cyanobacterial blooms were sampled in twenty-three Midwestern United States lakes and analyzed for community composition, thirteen cyanotoxins by liquid chromatography/mass spectrometry and immunoassay...
Authors
Jennifer L. Graham, Keith A. Loftin, Michael T. Meyer, Andrew C. Ziegler
Comparison of two cell lysis procedures for recovery of microcystins in water samples from silver lake in Dover, Delaware, with microcystin producing cyanobacterial accumulations
A collaboration was developed between Abraxis, LLC, the State of Delaware Department of Natural Resources and Environmental Control Division of Water Resources Environmental Laboratory, the University of Delaware, and the United States Geological Survey to investigate the efficacy of the QuikLyse procedure developed by Abraxis, LLC as an alternative cell-lysis technique suitable for use...
Authors
Keith Loftin, Michael Frederick Meyer, Fernando Rubio, Lisa Kamp, Edythe Humphries, Ed Whereat
Algal toxins are a group of toxic compounds produced by a range of photosynthetic freshwater and marine plankton. These toxins have the ability to cause sickness in animals and humans and in severe cases lead to death. OGRL has the ability to evaluate and conduct occurrence, fate, transport, effects, and treatability studies methods.
Below are multimedia items associated with this project.
Below are publications associated with this project.
Land use patterns, ecoregion, and microcystin relationships in U.S. lakes and reservoirs: a preliminary evaluation
A statistically significant association was found between the concentration of total microcystin, a common class of cyanotoxins, in surface waters of lakes and reservoirs in the continental U.S. with watershed land use using data from 1156 water bodies sampled between May and October 2007 as part of the USEPA National Lakes Assessment. Nearly two thirds (65.8%) of the samples with...
Authors
John R. Beaver, Erin E. Manis, Keith Loftin, Jennifer L. Graham, Amina Pollard, Richard S. Mitchell
A review on cylindrospermopsin: the global occurrence, detection, toxicity and degradation of a potent cyanotoxin
Cylindrospermopsin is an important cyanobacterial toxin found in water bodies worldwide. The ever-increasing and global occurrence of massive and prolonged blooms of cylindrospermopsin-producing cyanobacteria poses a potential threat to both human and ecosystem health. Its toxicity is associated with metabolic activation and may involve mechanisms that adversely affect a wide variety of...
Authors
Armah A. de la Cruz, Anastasia Hiskia, Triantafyllos Kaloudis, Neil Chernoff, Donna Hill, Maria G. Antoniou, Xuexiang He, Keith Loftin, Kevin O'Shea, Cen Zhao, Miguel Pelaez, Changseok Han, Trevor J. Lynch, Dionysios D. Dionysiou
Relations between DNA- and RNA-based molecular methods for cyanobacteria and microcystin concentration at Maumee Bay State Park Lakeside Beach, Oregon, Ohio, 2012
Water samples were collected from Maumee Bay State Park Lakeside Beach, Oregon, Ohio, during the 2012 recreational season and analyzed for selected cyanobacteria gene sequences by DNA-based quantitative polymerase chain reaction (qPCR) and RNA-based quantitative reverse-transcription polymerase chain reaction (qRT-PCR). Results from the four DNA assays (for quantifying total...
Authors
Erin Stelzer, Keith Loftin, Pamela Struffolino
Cyanotoxin mixtures and taste-and-odor compounds in cyanobacterial blooms from the midwestern united states
The mixtures of toxins and taste-and-odor compounds present during cyanobacterial blooms are not well characterized and of particular concern when evaluating potential human health risks. Cyanobacterial blooms were sampled in twenty-three Midwestern United States lakes and analyzed for community composition, thirteen cyanotoxins by liquid chromatography/mass spectrometry and immunoassay...
Authors
Jennifer L. Graham, Keith A. Loftin, Michael T. Meyer, Andrew C. Ziegler
Comparison of two cell lysis procedures for recovery of microcystins in water samples from silver lake in Dover, Delaware, with microcystin producing cyanobacterial accumulations
A collaboration was developed between Abraxis, LLC, the State of Delaware Department of Natural Resources and Environmental Control Division of Water Resources Environmental Laboratory, the University of Delaware, and the United States Geological Survey to investigate the efficacy of the QuikLyse procedure developed by Abraxis, LLC as an alternative cell-lysis technique suitable for use...
Authors
Keith Loftin, Michael Frederick Meyer, Fernando Rubio, Lisa Kamp, Edythe Humphries, Ed Whereat