Publications

Below is a sampling of Laboratory for Infectious Disease and the Environment publications.

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March 1, 2016

Determining the 95% limit of detection for waterborne pathogen analyses from primary concentration to qPCR Determining the 95% limit of detection for waterborne pathogen analyses from primary concentration to qPCR

The limit of detection (LOD) for qPCR-based analyses is not consistently defined or determined in studies on waterborne pathogens. Moreover, the LODs reported often reflect the qPCR assay alone rather than the entire sample process. Our objective was to develop an approach to determine the 95% LOD (lowest concentration at which 95% of positive samples are detected) for the entire process...

Authors

Joel P. Stokdyk, Aaron D. Firnstahl, Susan K. Spencer, Tucker R Burch, Mark A. Borchardt

Water Resources Mission Area, Upper Midwest Environmental Sciences Center, Upper Midwest Water Science Center, Laboratory for Infectious Disease and the Environment

January 1, 2011

Norovirus outbreak caused by a new septic system in a dolomite aquifer Norovirus outbreak caused by a new septic system in a dolomite aquifer

Septic systems that are built in compliance with regulations are generally not expected to be the cause of groundwater borne disease outbreaks, especially in areas with thick vadose zones. However, this case study demonstrates that a disease outbreak can occur in such a setting and outlines the combination of epidemiological, microbiological, and hydrogeological methods used to confirm...

Authors

M. A. Borchardt, K. R. Bradbury, E.C. Alexander, R.J. Kolberg, S.C. Alexander, John R. Archer, L.A. Braatz, B.M. Forest, J.A. Green, S. K. Spencer

Laboratory for Infectious Disease and the Environment