Endocrine Disruption

Scientists determined what happens to the neonicotinoid insecticide, imidacloprid, on coated wheat seeds once ingested by Japanese quail (Coturnix japonica)—a model species for free-range, seed-eating, upland game birds. Imidacloprid was found to be rapidly adsorbed, metabolized, and excreted, and resulted in no overt signs of toxicity during a controlled laboratory study.

In a series of studies from 2010 to 2018, U.S. Geological Survey (USGS) scientists detected low levels of legacy contaminants and pharmaceuticals in osprey ( Pandion haliaetus) and their food chain within the Chesapeake and Delaware River estuaries. Osprey reproductive success increased during the same period and was determined to be adequate to sustain a stable population in both estuaries.

Science from the U.S. Geological Survey (USGS) and other entities has shown that a mixture of natural and synthetic estrogens and other similar chemicals are discharged from wastewater treatment plants (WWTPs) to streams and rivers.

Our specialized teams of scientists are working in our laboratories and at field sites around the Great Lakes in collaboration with other federal and state resource agencies to document the prevalence of skin and liver tumors in fish. Tumor prevalence in white suckers ( Catostomus commersonii), a fish harvested as a food source by local communities, is related to the degree of urbanization in the...

The Bioactive Chemicals Research Laboratory applies a collaborative transdisciplinary approach to conduct research to minimize the risk to human and aquatic organism health from exposure to contaminants in water supplies.

About the Research The Environmental Chemistry Laboratory Core Technology Team (CTT) as part of the Environmental Health Program develops and applies innovative methods of sampling and analysis to answer critical questions about the occurrence, distribution, fate and transport, and biological exposure of chemical in all environmental matrices (water, air, tissues, sediments, and others).

The Fishing, Hunting, and Subsistence Living Integrated Science Team focuses on contaminant and pathogen exposures in the environment that could impact the presence and vitality of fish and wildlife populations that drive commercial, recreational and subsistence activities such as hunting and fishing. If actual risks are identified this project will inform how to economically and effectively...

Scientists optimized existing endocrine active chemical screening tests to improve their precision, accuracy, and ability to screen more samples in a shorter time-frame. The optimization was done to more rapidly obtain results from the bioassays so that research on the risks of endocrine active chemical exposure can proceed more rapidly.

The Chesapeake Bay is the largest estuary in the United States and provides critical resources to fish, wildlife and people. For more than a decade, recreational fish species have been plagued with skin lesions and intersex conditions (the presence of male and female sex characteristics in the same fish) that biologists attributed to exposures to endocrine disrupting chemicals (EDCs)...

Changes in the regulation and use of some organic chemicals have caused environmental concentrations to stabilize or decline during the past 35 years coincident with a rebound in the osprey ( Pandion haliaetus) population of the Chesapeake Bay.

Tree swallow eggs at most study sites in the Great Lakes basin were minimally exposed to legacy organic contaminants and brominated flame retardants.

Estrogens are recognized as modulators of immune responses in mammals, but how these effects might occur in fish was not understood. U.S. Geological Survey (USGS) scientists published findings that fish white blood cells (leukocytes) have specific estrogen receptors (ERs)—a discovery that moves scientists one step closer to understanding the connection between exposure to estrogenic substances and...