Bioassays

Refinement of the existing national-scale “de facto reuse incidence in our nation’s consumable supply” (DRINCS) model, complemented by field measurements, provides a screening tool to understand human and wildlife exposure to toxicants and pathogens associated with the incidental reuse of treated wastewater in the Shenandoah River watershed. The model results can be accessed in a companion web...

Raised black lesions observed in 30 percent of the brown bullhead collected from two sites in Lake Memphremagog from 2014 through 2017 were identified microscopically as malignant melanoma. Malignant melanoma in freshwater fishes has been reported before, but this cancer occurrence cluster is raising questions about the cause of the tumors and the implications for the long-term health of fish...

Science from the U.S. Geological Survey (USGS) and other entities has shown that a mixture of natural and synthetic estrogens and other similar chemicals are discharged from wastewater treatment plants (WWTPs) to streams and rivers.

The Fishing, Hunting, and Subsistence Living Integrated Science Team focuses on contaminant and pathogen exposures in the environment that could impact the presence and vitality of fish and wildlife populations that drive commercial, recreational and subsistence activities such as hunting and fishing. If actual risks are identified this project will inform how to economically and effectively...

Scientists optimized existing endocrine active chemical screening tests to improve their precision, accuracy, and ability to screen more samples in a shorter time-frame. The optimization was done to more rapidly obtain results from the bioassays so that research on the risks of endocrine active chemical exposure can proceed more rapidly.

The Chesapeake Bay is the largest estuary in the United States and provides critical resources to fish, wildlife and people. For more than a decade, recreational fish species have been plagued with skin lesions and intersex conditions (the presence of male and female sex characteristics in the same fish) that biologists attributed to exposures to endocrine disrupting chemicals (EDCs)...

Short-term laboratory exposure of adult fathead minnows to the human contraceptive progestin, gestodene (GES), at environmentally relevant concentrations induced rapid and negative effects on reproductive health and suggests that wild fish may be similarly affected.

Evidence indicating the presence of wastewaters from unconventional oil and gas (UOG) production was found in surface waters and surficial sediments near an UOG disposal facility in West Virginia.

The U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (EPA) are collaborating on a field-based study of chemical mixture composition and environmental effects in stream waters affected by a wide range of human activities and contaminant sources.

Testing of U.S. streams has detected glucocorticoid and androgen biological activity. In a collaborative study between the National Cancer Institute (NCI), Laboratory of Receptor Biology and Gene Expression, the U.S. Geological Survey (USGS), and others, scientists studied the potential for the biological activity in streams of glucocorticoids and androgens hormones—both potential endocrine...

“Legacy contaminants” and “contaminants of emerging concern” that persist in the environment are affecting the health of fish and wildlife in the Chesapeake Bay and its watershed. State continue to report impaired water resources due to the persistence and toxicity of some previously banned pollutants. In addition, other contaminants of emerging concern are released to the environment at levels...

Chemical contaminants including herbicides, veterinary pharmaceuticals, and biogenic hormones have been detected at fish nesting sites in the Potomac River watershed where endocrine disruption in smallmouth bass ( Micropterus dolomieu) was also observed. Although these contaminants are known to originate from a variety of human and animal-waste sources, results of a recent U.S. Geological Survey (...