Steve McCormick is a Scientist Emeritus at the Conte Anadromous Fish Research Laboratory in Turners Falls, MA.
Steve’s work has centered on the environmental and hormonal control of water and salt balance, development, growth and reproduction of anadromous fishes, including salmon, trout, shad, alewife, sturgeon and lamprey. This research has addressed important environmental issues including acidification, impacts of dams, endocrine disruptors and climate change, especially the impacts of temperature and salinity. The results of this work have been published in more than 190 papers and book chapters. Steve has been Chair of the Division of Comparative Endocrinology and member of the Executive Board of the Society of Integrative and Comparative Biology, and President and Current Member of the Executive Committee of the Physiology Section of the American Fisheries Society (AFS). He has been a visiting scientist at the University of Goteborg (1988) and Ocean Research Institute of the University of Tokyo (1990), James Chair Visiting Professor at St. Francis Xavier University, Nova Scotia, Canada (1999) and Visiting Scholar at Hokkaido University, Sapporo, Japan (2002). In 2014 he received the Excellence in Fish Physiology Award for lifetime achievement from the Physiology Section of AFS. He has been an adjunct Professor of Biology at the University of Massachusetts, Amherst since 1990 and Associate Editor of General and Comparative Endocrinology since 1996.
Professional Experience
1990-present Research Physiologist & Physiology Section Leader, Conte Anadromous Fish Research Center, USGS, Turners Falls, MA.
2016-present Senior Scientist, USGS
1998-1999 Acting Director, Conte Anadromous Fish Research Center, USGS, Biological Resources Division, Turners Falls, MA.
1989-1990 Research Fellow, Ocean Research Institute, University of Tokyo (with Professor Tetsuya Hirano, 4 months).
1986-1989 Postdoctoral Fellow (NIH) with Professor Howard A. Bern in the Department of Zoology, Univ. of California, Berkeley.
1983-1986 Postdoctoral Fellow, with Dr. Richard L. Saunders, Department of Fisheries and Oceans, St. Andrews Biological Station, New Brunswick, Canada.
Education and Certifications
Ph.D., 1983, Massachusetts Institute of Technology and Woods Hole Oceanography Joint Program in Oceanography, Cambridge and Woods Hole, MA USA
Affiliations and Memberships*
1990-present, Adjunct Professor, Department of Biology, University of Massachusetts, Amherst.
1992-present, Adjunct Professor, Department of Environmental Conservation, University of Massachusetts, Amherst.
1993 Member, Organismic and Evolutionary Biology Program, University of Massachusetts, Amherst.
Science and Products
Osmoregulation and acid-base balance.
Discovery of prolactin-like in lamprey: Role in osmoregulation and new insight into the evolution of the growth hormone/prolactin family
Evaluating acid-aluminum stress in streams of the Northeastern U.S. at watershed, fish community and physiological scales
Juvenile sea lamprey (Petromyzon marinus) have a wide window of elevated salinity tolerance that is eventually limited during springtime warming
Metabolic costs associated with seawater acclimation in a euryhaline teleost, the fourspine stickleback (Apeltes quadracus)
Na+/HCO3- cotransporter 1 (nbce1) isoform gene expression during smoltification and seawater acclimation of Atlantic salmon
Repeated genetic targets of natural selection underlying adaptation of euryhaline fishes to changing salinity
Neuroendocrine regulation of plasma cortisol levels during smoltification and seawater acclimation of Atlantic salmon
Identification of supraoptimal temperatures in juvenile blueback herring (Alosa aestivalis) using survival, growth rate and scaled energy reserves
Tissue and salinity specific Na+/Cl− cotransporter (NCC) orthologues involved in the adaptive osmoregulation of sea lamprey (Petromyzon marinus)
Rapid embryonic development supports the early onset of gill functions in two coral reef damselfishes
Survival and spawning success of American shad (Alosa sapidissima) in varying temperatures and levels of glochidia infection
Non-USGS Publications**
**Disclaimer: The views expressed in Non-USGS publications are those of the author and do not represent the views of the USGS, Department of the Interior, or the U.S. Government.
Understanding Brook Trout Persistence in Warming Streams
Effects of temperature and energy use on fish passage and spawning success of American shad
Sockeye Salmon Migrating at the Northern Edge of Their Distribution
Assessing heat stress in migrating Yukon River Chinook Salmon
Fish Physiology
Gene Transcription and Heat Shock Protein 70 Abundance Results from Migrating Adult Chinook Salmon, Yukon Watershed, 2016-2017
Physiological changes in response to salinity and cortisol treatment in Atlantic sturgeon
Science and Products
- Publications
Filter Total Items: 207
Osmoregulation and acid-base balance.
Maintaining relatively constant levels of internal cellular ions is critical to the normal function of all animals. For many organisms this is achieved primarily by regulating the ion and acid-base composition of the blood within narrow limits. This understanding of the importance of “le milieu interior,” first espoused by Claude Bernard in the mid-1800s and later described as “homeostasis” by WalAuthorsStephen D. McCormick, Eric T. Schultz, Colin BraunerDiscovery of prolactin-like in lamprey: Role in osmoregulation and new insight into the evolution of the growth hormone/prolactin family
We used a representative of one of the oldest extant vertebrate lineages (jawless fish or agnathans) to investigate the early evolution and function of the growth hormone (GH)/prolactin (PRL) family. We identified a second member of the GH/PRL family in an agnathan, the sea lamprey (Petromyzon marinus). Structural, phylogenetic, and synteny analyses supported the identification of this hormone asAuthorsNingping Gong, Diogo Ferreira-Martins, Jessica L. Norstog, Stephen D. McCormick, Mark SheridanEvaluating acid-aluminum stress in streams of the Northeastern U.S. at watershed, fish community and physiological scales
In spite of overall improvements in air and water quality, biological stress from low pH and high concentrations of inorganic aluminum continue to impact fish and fish habitat in northeastern North America, with independent and interactive effects on individuals, populations and communities. Integrative indicators can therefore be useful in monitoring both impact and recovery across multiple scaleAuthorsBenjamin J Zdasiuk, Celia Y. Chen, Stephen D. McCormick, Keith H. Nislow, Joel G Singley, John T. KellyJuvenile sea lamprey (Petromyzon marinus) have a wide window of elevated salinity tolerance that is eventually limited during springtime warming
The present study examined changes in biometric characteristics, osmoregulatory capacity, and seawater (SW) tolerance of juvenile sea lamprey (Petromyzon marinus) throughout the varying thermal changes from late autumn to late spring. Body length, mass, and condition factor were maintained until April, when significant declines in mass and condition factor were observed to correspond with increaseAuthorsCiaran A. Shaugnessy, Stephen D. McCormickMetabolic costs associated with seawater acclimation in a euryhaline teleost, the fourspine stickleback (Apeltes quadracus)
The cost of osmoregulation in teleosts has been debated for decades, with estimates ranging from one to 30 % of routine metabolic rate. The variation in the energy budget appears to be greater for euryhaline fish due to their ability to withstand dynamic salinity levels. In this study, a time course of metabolic and physiological responses of the euryhaline fourspine stickleback (Apeltes quadracusAuthorsJessica L. Norstog, Stephen D. McCormick, John T. KellyNa+/HCO3- cotransporter 1 (nbce1) isoform gene expression during smoltification and seawater acclimation of Atlantic salmon
The life history of Atlantic salmon (Salmo salar) includes an initial freshwater phase (parr) that precedes a springtime migration to marine environments as smolts. The development of osmoregulatory systems that will ultimately support the survival of juveniles upon entry into marine habitats is a key aspect of smoltification. While the acquisition of seawater tolerance in all euryhaline species dAuthorsJason P. Breves, Ian S. McKay, Victor Koltenyuk, Nastasia N. Nelson, Sean C. Lema, Stephen D. McCormickRepeated genetic targets of natural selection underlying adaptation of euryhaline fishes to changing salinity
Ecological transitions across salinity boundaries have led to some of the most important diversification events in the animal kingdom, especially among fishes. Adaptations accompanying such transitions include changes in morphology, diet, whole-organism performance, and osmoregulatory function, which may be particularly prominent since divergent salinity regimes make opposing demands on systems thAuthorsJonathan P Velotta, Stephen D. McCormick, Andrew Whitehead, Catherine S Durso, Eric T. SchultzNeuroendocrine regulation of plasma cortisol levels during smoltification and seawater acclimation of Atlantic salmon
Diadromous fishes undergo dramatic changes in osmoregulatory capacity in preparation for migration between freshwater and seawater. One of the primary hormones involved in coordinating these changes is the glucocorticoid hormone, cortisol. In Atlantic salmon (Salmo salar), cortisol levels increase during the spring smoltification period prior to seawater migration; however, the neuroendocrine factAuthorsBrett M Culbert, Amy M. Regish, Daniel J Hall, Stephen D. McCormick, Nicholas J. BernierIdentification of supraoptimal temperatures in juvenile blueback herring (Alosa aestivalis) using survival, growth rate and scaled energy reserves
For young fishes, growth of somatic tissues and energy reserves are critical steps for survival and progressing to subsequent life stages. When thermal regimes become supraoptimal, routine metabolic rates increase and leave less energy for young fish to maintain fitness-based activities and, in the case of anadromous fishes, less energy to prepare for emigration to coastal habitats. Thus, understaAuthorsLian Guo, Adrian Jordaan, Eric T. Schultz, Stephen D. McCormickTissue and salinity specific Na+/Cl− cotransporter (NCC) orthologues involved in the adaptive osmoregulation of sea lamprey (Petromyzon marinus)
Two orthologues of the gene encoding the Na+-Cl− cotransporter (NCC), termed ncca and nccb, were found in the sea lamprey genome. No gene encoding the Na+-K+-2Cl− cotransporter 2 (nkcc2) was identified. In a phylogenetic comparison among other vertebrate NCC and NKCC sequences, the sea lamprey NCCs occupied basal positions within the NCC clades. In freshwater, ncca mRNA was found only in the gillAuthorsAndre Barany-Ruiz, Ciaran S Shaughnessy, Ryan M. Pelis, Juan Fuentes, Juan M Mancera, Stephen D. McCormickRapid embryonic development supports the early onset of gill functions in two coral reef damselfishes
The gill is one of the most important organs for growth and survival of fishes. Early life stages in coral reef fishes often exhibit extreme physiological and demographic characteristics that are linked to well-established respiratory and ionoregulatory processes. However, gill development and function in coral reef fishes is not well-understood. Therefore, we investigated gill morphology, oxygenAuthorsLA Prescott, Amy M. Regish, SJ McMahon, Stephen D. McCormick, JL RummerSurvival and spawning success of American shad (Alosa sapidissima) in varying temperatures and levels of glochidia infection
Temperature fluctuations and climate change impacts may substantially affect spawning success of fish, especially migratory species with a limited spawning window. Factors affecting American shad (Alosa sapidissima) spawning success and survival were investigated at different temperatures and periods (peak- and late-spawning periods) during the Connecticut River, USA, spawning migration in 2017. WAuthorsShannon M Bayse, Amy M. Regish, Stephen D. McCormickNon-USGS Publications**
Yoshikawa, J.S.M., McCormick, S.D., Young, G. and Bern, H.A. 1993. Effects of salinity on chloride cell morphology and density, and Na+,K+-ATPase activity in the teleost Gillichthys mirabilis. Comparative Biochemistry and Physiology 105: 311-317.McCormick, S.D., S. Hasegawa and T. Hirano. 1992. Calcium uptake in the skin of a fresh water teleost. Proceedings of the National Academy of Sciences 89: 3635-3638.
McCormick, S.D., Tsai, P.I., Kelley, K.M., Nishioka, R.S. and Bern, H.A. 1992. Stimulation of coho salmon growth by insulin-like growth factor I. General and Comparative Endocrinology 86: 398-406.McCormick, S.D., Tsai, P.I., Kelley, K.M., Nishioka, R.S. and Bern, H.A. 1991. Hormonal control of sulfate uptake by branchial cartilage of coho salmon: role of IGF-I. Journal of Experimental Zoology 262: 166-171.Bern, H.A., McCormick, S.D., Kelley, K.M., Gray, E.S., Nishioka, R.S., Madsen, S.S. and Tsai, P.I. 1991. Insulin-like growth factors "under water": role in growth and function of fish and other poikilothermic vertebrates. In: Modern Concepts of Insulin-Like Growth Factors. Ed.: E.M. Spencer. Elsevier Press, New York. Pp. 85-96.McCormick, S.D., Dickhoff, W.W., Duston, J., Nishioka, R.S. and Bern, H.A. 1991. Developmental differences in the responsiveness of gill Na+,K+-ATPase to cortisol in salmonids. General and Comparative Endocrinology 84: 308-317.McCormick, S.D., T. Sakamoto, S. Hasegawa and T. Hirano. 1991. Osmoregulatory actions of insulin-like growth factor I in rainbow trout (Oncorhynchus mykiss). Journal of Endocrinology 130: 87-92.Herndon, T., S.D. McCormick and H.A. Bern. 1991. Effects of prolactin on chloride cells in opercular membrane of seawater-adapted tilapia. General and Comparative Endocrinology 83: 283-289.McCormick, S.D. 1990. Cortisol directly stimulates differentiation of chloride cells in tilapia opercular membrane (Oreochromis mossambicus). American Journal Physiology 259: R857-R863.McCormick, S.D. 1990. Fluorescent labelling of Na+,K+-ATPase in intact cells using a fluorescent derivative of ouabain. Cell and Tissue Research 260: 529-533.McCormick, S.D. and R.L. Saunders. 1990. Influence of ration level and salinity on circulating levels of thyroid hormones in Atlantic salmon (Salmo salar). General and Comparative Endocrinology 78: 224-230.Montgomery, W.L., S.D. McCormick, R.J. Naiman, F.G. Whoriskey and G. Black. 1989. Migration and use of marine resources by brook charr (Salvelinus fontinalis) in the Moisie River, Quebec. Polish Archives of Hydrobiology 37: 43-61.McCormick, S.D., R.L. Saunders and A.D. MacIntyre. 1989. The effect of salinity and ration level on growth rate and conversion efficiency in Atlantic salmon smolts. Aquaculture 82: 173-180.McCormick S.D. and H.A. Bern. 1989. In vitro stimulation of Na+,K+-ATPase activity and ouabain binding by cortisol in coho salmon gill. American Journal Physiology 256: R707-R715.McCormick, S.D., C.D. Moyes and J.S. Ballantyne. 1989. Influence of salinity on the energetics of gill and kidney of Atlantic salmon (Salmo salar). Fish Physiology and Biochemistry 6: 243-254.McCormick, S.D., R.L. Saunders and A.D. MacIntyre. 1989. Mitochondrial enzyme activity, and ion regulation during parr-smolt transformation of Atlantic salmon (Salmo salar). Fish Physiology and Biochemistry 6: 231-241Young, P.S., S.D. McCormick, J.R. Demarest, R.J. Lin, R.S. Nishioka, and H.A. Bern. 1988. Effects of salinity, hypophysectomy and prolactin on whole-animal transepithelial potential in the tilapia Oreochromis mossambicus. General and Comparative Endocrinology 71: 389-397.Wildish, D.J., D.D. Kristmanson, R.L. Hoar, A.M. DeCoste, S.D. McCormick and A.W. White. 1987. Giant scallop feeding and growth response to flow. Journal of Experimental Marine Biology and Ecology 113: 207-220.Naiman, R.J., S.D. McCormick, W.L. Montgomery and R. Morin. 1987. Anadromous brook charr, Salvelinus fontinalis: opportunities and constraints for population enhancement. Marine Fisheries Review 49: 1-13.**Disclaimer: The views expressed in Non-USGS publications are those of the author and do not represent the views of the USGS, Department of the Interior, or the U.S. Government.
- Science
Understanding Brook Trout Persistence in Warming Streams
Cold-water adapted Brook Trout were historically widely distributed – ranging from northern Quebec to Georgia, and from the Atlantic Ocean to Manitoba in the north, and along the Appalachian ridge in the south. However, studies show that due to factors associated with climate change, such as increased stream temperature and changing water flow, the number of streams containing Brook Trout is decli...Effects of temperature and energy use on fish passage and spawning success of American shad
American Shad are the most numerous and economically important anadromous species on the east coast of the United States. Yet in many river systems their populations have experienced declines, primarily due to the impacts of dams and habitat loss.Sockeye Salmon Migrating at the Northern Edge of Their Distribution
The physiological challenge for anadromous fish to migrate upriver to spawn and complete their life cycle is influenced by river temperature.Assessing heat stress in migrating Yukon River Chinook Salmon
We will examine evidence of heat stress in Yukon River Chinook salmon (Oncorhynchus tshawytscha) using heat shock proteins and gene expression.Fish Physiology
Physiological demands are especially important to anadromous fish because of their need to move between freshwater and seawater and to make long, often difficult migrations. - Data
Gene Transcription and Heat Shock Protein 70 Abundance Results from Migrating Adult Chinook Salmon, Yukon Watershed, 2016-2017
This data set documents the gene transcription levels for a panel of 12 selected genes and the heat shock protein 70 (HSP70) protein abundance measured in the muscle tissue of individual wild Chinook salmon captured from locations within the U.S. portion of the Yukon River watershed. Chinook salmon were primarily captured in 2016 and 2017 from existing field efforts (n = 477). A small number of adPhysiological changes in response to salinity and cortisol treatment in Atlantic sturgeon
The dataset are the results of studies examining the osmoregulatory physiology of Atlantic sturgeon (Acipenser oxyrinchus). Two experiments were conducted on physiological responses to salinity change, and another experiment on the effects of cortisol treatment on osmoregulation. - Multimedia
- News
*Disclaimer: Listing outside positions with professional scientific organizations on this Staff Profile are for informational purposes only and do not constitute an endorsement of those professional scientific organizations or their activities by the USGS, Department of the Interior, or U.S. Government