Study Highlights the Complexity of Chemical Mixtures in United States Streams
Collecting Water-Quality Samples from the Enoree River, SC
Processing Water-Quality Samples Collected from the Enoree River, SC
A new study highlights the complexity of chemical mixtures in streams and advances the understanding of wildlife and human exposure to complex chemical mixtures.
Chemical contaminants do not occur alone in our water resources and detections of complex chemical mixtures are commonly documented in rivers and streams across the United States. Fish and other wildlife are exposed to these complex mixtures of chemicals. There is also the potential for human exposure through direct skin absorption, ingestion of contaminated drinking water, or consumption of contaminated wildlife.
This study builds on previous work that identified mixtures of contaminants in streams across the United States. The U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (EPA) collaborated to assess more than 700 organic chemicals as well as indicators of biological effects in 38 streams within the United States, which represented one of the most comprehensive set of contaminants ever monitored at individual stream sites. This study was an opportunity to assess the factors related to site-to-site differences in stream-contaminant complexity and to put the chemical data into context with potential effects on aquatic animal health.
The results indicate that the mixtures of chemicals in streams reflect combined contaminant contributions originating from a combination of agricultural, industrial, municipal, and residential sources in individual watersheds. Complex chemical mixtures (a range of 4 to 161 chemicals per stream) were detected in streams across a range of urban and agricultural areas in the United States. As expected, fewer chemicals were detected in the 4 streams that had low population density compared to the 34 urban/agricultural-influenced locations.
Indicators of biological activity, such as estrogen receptor activation, were present in all stream samples except for one reference site. Estrogenicity activity values have yet to be firmly established; however, multiple sites exceeded activity levels estimated to signal potential adverse effects on aquatic organisms. The indicators were related to target chemicals in the water samples to different degrees, which advanced our understanding of exposure and relative risk of specific chemicals and mixtures.
The results of this overall effort yield insights into the complexity of chemical mixtures present in a wide range of surface waters across the United States and their potential for eliciting adverse ecological health consequences. These results are important to answer questions about minimizing health risks and economic costs, if any, associated with mixed-contaminant exposures.
The USGS Environmental Health Program (Toxic Substances Hydrology and Contaminant Biology), the EPA Safe and Sustainable Water Resources, and the Chemical Safety for Sustainability Research Programs funded this study.
Related research is listed below.
Drinking Water and Wastewater Infrastructure Science Team
Food Resources Lifecycle Integrated Science Team
Sources of Contaminants to Congaree National Park—USGS and National Park Service Working Together
Recovery of Stream and Adjacent Groundwater After Wastewater Treatment Facility Closure
Chemical Mixtures and Environmental Effects
Long-Term Study Finds Endocrine Disrupting Chemicals in Urban Waterways
Assessing Environmental Chemical Mixtures in United States Streams
Chemical Combo and Intersex Fish Found at Smallmouth Bass Nesting Sites
Complex Mixture of Contaminants Persists in Streams Miles from the Source
Below are data or web applications associated with this project.
Targeted-Organic-Chemical Analysis Concentration Data for Surface-Water Samples Collected from 38 Stream Sites across the USA during 2012-2014
Below are publications associated with this research.
Expanded target-chemical analysis reveals extensive mixed-organic-contaminant exposure in USA streams
Occurrence and in vitro bioactivity of estrogen, androgen, and glucocorticoid compounds in a nationwide screen of United States stream waters
Methods used to characterize the chemical composition and biological activity of environmental waters throughout the United States, 2012-14
A new study highlights the complexity of chemical mixtures in streams and advances the understanding of wildlife and human exposure to complex chemical mixtures.
Chemical contaminants do not occur alone in our water resources and detections of complex chemical mixtures are commonly documented in rivers and streams across the United States. Fish and other wildlife are exposed to these complex mixtures of chemicals. There is also the potential for human exposure through direct skin absorption, ingestion of contaminated drinking water, or consumption of contaminated wildlife.
This study builds on previous work that identified mixtures of contaminants in streams across the United States. The U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (EPA) collaborated to assess more than 700 organic chemicals as well as indicators of biological effects in 38 streams within the United States, which represented one of the most comprehensive set of contaminants ever monitored at individual stream sites. This study was an opportunity to assess the factors related to site-to-site differences in stream-contaminant complexity and to put the chemical data into context with potential effects on aquatic animal health.
The results indicate that the mixtures of chemicals in streams reflect combined contaminant contributions originating from a combination of agricultural, industrial, municipal, and residential sources in individual watersheds. Complex chemical mixtures (a range of 4 to 161 chemicals per stream) were detected in streams across a range of urban and agricultural areas in the United States. As expected, fewer chemicals were detected in the 4 streams that had low population density compared to the 34 urban/agricultural-influenced locations.
Indicators of biological activity, such as estrogen receptor activation, were present in all stream samples except for one reference site. Estrogenicity activity values have yet to be firmly established; however, multiple sites exceeded activity levels estimated to signal potential adverse effects on aquatic organisms. The indicators were related to target chemicals in the water samples to different degrees, which advanced our understanding of exposure and relative risk of specific chemicals and mixtures.
The results of this overall effort yield insights into the complexity of chemical mixtures present in a wide range of surface waters across the United States and their potential for eliciting adverse ecological health consequences. These results are important to answer questions about minimizing health risks and economic costs, if any, associated with mixed-contaminant exposures.
The USGS Environmental Health Program (Toxic Substances Hydrology and Contaminant Biology), the EPA Safe and Sustainable Water Resources, and the Chemical Safety for Sustainability Research Programs funded this study.
Related research is listed below.
Drinking Water and Wastewater Infrastructure Science Team
Food Resources Lifecycle Integrated Science Team
Sources of Contaminants to Congaree National Park—USGS and National Park Service Working Together
Recovery of Stream and Adjacent Groundwater After Wastewater Treatment Facility Closure
Chemical Mixtures and Environmental Effects
Long-Term Study Finds Endocrine Disrupting Chemicals in Urban Waterways
Assessing Environmental Chemical Mixtures in United States Streams
Chemical Combo and Intersex Fish Found at Smallmouth Bass Nesting Sites
Complex Mixture of Contaminants Persists in Streams Miles from the Source
Below are data or web applications associated with this project.
Targeted-Organic-Chemical Analysis Concentration Data for Surface-Water Samples Collected from 38 Stream Sites across the USA during 2012-2014
Below are publications associated with this research.