Paul M Bradley
Science and Products
Environmental Health Program Drinking Water Science
Drinking water in the United States rarely is tested for contaminants and pathogens at the tap, where human exposure can occur. In this special issue, we present the science to help understand contaminants and pathogens in drinking water at business and residential taps.
Mixtures of Organic and Inorganic Chemicals Characterized in Water from the Taps of Residences in the Greater Chicago Area— Science to Understand Contaminant Exposures in Drinking Water
As a component of ongoing research with a coalition of partners, including the U.S. Geological Survey U.S. Environmental Protection Agency, National Institute of Environmental Health Sciences, Colorado School of Mines, University of Illinois Chicago, and University of South Carolina, water was collected from the taps of 45 Chicago-area residences and analyzed for 540 organic and 35...
Ongoing Research to Characterize the Complexity of Chemical Mixtures in Water Resources—Urban Stormwater
A multiagency reconnaissance study of chemicals in urban stormwater, sampled from pipes or ditches during 50 runoff events at 21 sites in 17 states across the United States, demonstrated that stormwater runoff contains complex mixtures of chemicals including polycyclic aromatic hydrocarbons, pesticides, and pharmaceuticals that are indicative of multiple sources in the watershed.
Pilot Study Provides Information on Contaminant Exposure from Tap Water at Residential and Workplace Sites in the United States
The U.S. Geological Survey (USGS), in collaboration with National Institutes of Health, U.S. Environmental Protection Agency, and academia, completed a pilot study to provide information on contaminant exposure from tap water at 26 locations including public and private supplies. Public-supply tap water generally met enforceable standards for those compounds with standards. Samples consisted...
Water and Wastewater Infrastructure Science Team
The team studies toxicants and pathogens in water resources from their sources, through watersheds, aquifers, and infrastructure to human and wildlife exposures. That information is used to develop decision tools that protect human and wildlife health.
Sources of Contaminants to Congaree National Park—USGS and National Park Service Working Together
A National Park Service (NPS) and U.S. Geological Survey (USGS) study determined the concentrations, potential for degradation, and potential for aquatic and terrestrial animal exposure to organic contaminants in water and sediment within the flood-plain/aquatic environments of Congaree National Park which is located downstream from urban and...
Study Highlights the Complexity of Chemical Mixtures in United States Streams
A new study highlights the complexity of chemical mixtures in streams and advances the understanding of wildlife and human exposure to complex chemical mixtures.
Recovery of Stream and Adjacent Groundwater After Wastewater Treatment Facility Closure
The hydrology and chemistry of a wastewater-impacted stream and adjacent groundwater responded rapidly (had fewer chemicals at lower concentrations) following wastewater treatment facility shutdown. However, the adjacent shallow groundwater remained a continuing source of some wastewater-derived contaminants to the stream at least 1 year post-shutdown.
U.S. Geological Survey Scientists Complete First Systematic Regional Survey of Algal Toxins in Streams of the Southeastern United States
U.S. Geological Survey (USGS) scientists detected microcystin—an algal toxin—in 39 percent of 75 streams assessed in the southeastern United States. These results will inform and become part of a larger, systematic national survey of algal toxins in small streams of the United States.
Assessing Environmental Chemical Mixtures in United States Streams
The U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (EPA) are collaborating on a field-based study of chemical mixture composition and environmental effects in stream waters affected by a wide range of human activities and contaminant sources.
Contaminant Transport Models Aid in Understanding Trends of Chlorinated Ethenes in Public Supply Wells
U.S. Geological Survey (USGS) scientists used a mass–balance solute–transport model to enhance an understanding of factors affecting chlorinated ethene (CE) concentrations in a public supply well. They found that long–term simulated and measured CEconcentrations were affected by dense nonaqueous phase liquid (DNAPL) volume, composition, and by the bioavailability of organic carbon that drives...
Endocrine Disrupting Chemicals Persist Downstream from the Source
Endocrine disrupting chemicals (EDCs) were transported 2 kilometers downstream of a wastewater treatment plant (WWTP) outfall in a coastal plain stream. EDCs persisted downstream of the outfall with little change in the numbers of EDCs and limited decreases in EDC concentrations.
Effects-based monitoring of bioactive chemicals discharged to the Colorado River before and after a municipal wastewater treatment plant replacement
Monitoring of the Colorado River near the Moab, Utah, wastewater treatment plant (WWTP) outflow has detected pharmaceuticals, hormones, and estrogen-receptor (ER)-, glucocorticoid receptor (GR)-, and peroxisome proliferator-activated receptor-gamma (PPARγ)-mediated biological activities. The aim of the present multi-year study was to assess...
Cavallin, J.E.; Battaglin, William A.; Beihoffer, Jon; Blackwell, Bradley D.; Bradley, Paul; Cole, AR; Ekman, Drew R.; Hofer, R; Kinsey, J; Keteles, Kristen; Weissinger, R; Winkelman, Dana L.; Villeneuve, Daniel L.
Effects of stormwater runoff from selected bridge decks on conditions of water, sediment, and biological quality in receiving waters in South Carolina, 2013 to 2018
The U.S. Geological Survey, in cooperation with the South Carolina Department of Transportation, investigated the effects of stormwater runoff from bridge decks on stream water quality conditions in South Carolina. The investigation assessed 5 bridges in 3 physiographic provinces in South Carolina (Piedmont, Upper Coastal Plain, and Lower Coast...
Journey, Celeste A.; Petkewich, Matthew; Conlon, Kevin J.; Caldwell, Andral W.; Clark, Jimmy M.; Riley, Jeffrey W.; Bradley, Paul M. Evaluating the potential role of bioactive chemicals on the distribution of invasive Asian carp upstream and downstream from river mile 278 in the Illinois waterway
Two non-native carp species have invaded the Illinois Waterway and are a threat to Great Lakes ecosystems. Poor water quality in the upper Illinois Waterway, may be a factor contributing to the stalling of the carp population front near river mile 278. In 2015, the U.S. Geological Survey collected 4 sets of water samples from two sites upstream...
Battaglin, William A.; Duncker, James J.; Terrio, Paul J.; Bradley, Paul; Barber, Larry; DeCicco, Laura A. Methylmercury-Total mercury ratios in predator and primary consumer insects from Adirondack streams (New York, USA)
Mercury (Hg) is a global pollutant that affects biota in remote settings due to atmospheric deposition of inorganic Hg, and its conversion to methylmercury (MeHg), the bioaccumulating and toxic form. Characterizing biotic MeHg is important for evaluating aquatic ecosystem responses to changes in Hg inputs. Aquatic insects possess many qualities...
Riva-Murray, Karen; Bradley, Paul; Brigham, Mark E. Landfill leachate contributes per-/poly-fluoroalkyl substances (PFAS) and pharmaceuticals to municipal wastewater
Widespread disposal of landfill leachate to municipal sewer infrastructure in the United States calls for an improved understanding of the relative organic-chemical contributions to the wastewater treatment plant (WWTP) waste stream and associated surface-water discharge to receptors in the environment. Landfill leachate, WWTP influent, and WWTP...
Masoner, Jason R.; Kolpin, Dana W.; Cozzarelli, Isabelle M.; Smalling, Kelly L.; Bolyard, Stephanie; Field, Jennifer; Furlong, Edward T.; Gray, James L.; Lozinski, Duncan; Reinhart, Debra; Rodowa, Alix; Bradley, Paul M. Multi-region assessment of pharmaceutical exposures and predicted effects in USA wadeable urban-gradient streams
Human-use pharmaceuticals in urban streams link aquatic-ecosystem health to human health. Pharmaceutical mixtures have been widely reported in larger streams due to historical emphasis on wastewater-treatment plant (WWTP) sources, with limited investigation of pharmaceutical exposures and potential effects in smaller headwater streams. In 2014–...
Bradley, Paul; Journey, Celeste A.; Button, Daniel T.; Carlisle, Daren; Huffman, B.J.; Qi, Sharon L.; Romanok, Kristin; Van Metre, Peter C. Exposure and potential effects of pesticides and pharmaceuticals in protected streams of the US National Park Service southeast Region
Globally protected areas offer refugia for a broad range of taxa including threatened and endangered species. The United States National Park Service (NPS) manages public lands to preserve biodiversity, but increasing park visitation and development of surrounding landscapes increase exposure to and effects from bioactive contaminants. The risk (...
Bradley, Paul; Romanok, Kristin; Duncan, Jeffrey R.; Battaglin, William; Clark, Jimmy; Hladik, Michelle; Huffman, Bradley; Iwanowicz, Luke; Journey, Celeste A.; Smalling, Kelly Projected urban growth in the Southeastern USA puts small streams at risk
Future land-use development has the potential to profoundly affect the health of aquatic ecosystems in the coming decades. We developed regression models predicting the loss of sensitive fish (R2=0.39) and macroinvertebrate (R2=0.64) taxa as a function of urban and agricultural land uses and applied them to projected urbanization of the rapidly...
Van Metre, Peter C.; Waite, Ian R.; Qi, Sharon L.; Mahler, Barbara; Terando, Adam; Wieczorek, Michael; Meador, Michael R.; Bradley, Paul M.; Journey, Celeste A.; Schmidt, Travis S.; Carlisle, Daren Urban stormwater: An overlooked pathway of extensive mixed contaminants to surface and groundwaters in the United States
Increasing global reliance on stormwater control measures to reduce discharge to surface water, increase groundwater recharge, and minimize contaminant delivery to receiving waterbodies necessitates improved understanding of stormwater-contaminant profiles. A multi-agency study of organic and inorganic chemicals in urban stormwater from 50 runoff...
Masoner, Jason R.; Kolpin, Dana W.; Cozzarelli, Isabelle M.; Barber, Larry B.; Burden, D.S.; Foreman, William T.; Forshay, Kenneth J.; Furlong, Edward; Groves, Justin F.; Hladik, Michelle; Hopton, Matthew E.; Jaeschke, Jeanne B.; Keefe, Steffanie H.; Krabbenhoft, David; Lowrance , Richard; Romanok, Kristin; Rus, David L.; Selbig, William R.; Williams, Brad; Bradley, Paul Predictive analysis using chemical-gene interaction networks consistent with observed endocrine activity and mutagenicity of U.S. streams
In a recent U.S. Geological Survey/U.S. Environmental Protection Agency study assessing >700 organic compounds in 38 streams, in vitro assays indicated generally low estrogen, androgen, and glucocorticoid receptor activities, but identified 13 surface waters with 17β estradiol equivalent (E2Eq) activities greater than the 1 ng/L level of...
Berninger, Jason P.; DeMarini, David M.; Warren, Sarah H.; Simmons, Jane Ellen; Wilson, Vickie S.; Conley, Justin M.; Armstrong, Mikayla D.; Kolpin, Dana W.; Kuivila, Kathryn; Reilly, Timothy J.; Romanok, Kristin M.; Villeneuve, Daniel L.; Bradley, Paul M.; Iwanowicz, Luke R. Potential toxicity of complex mixtures in surface waters from a nationwide survey of United States streams: Identifying in vitro bioactivities and causative chemicals
While chemical analysis of contaminant mixtures remains an essential component of environmental monitoring, bioactivity-based assessments using in vitro systems increasingly play a role in the detection of biological effects. Historically, in vitro assessments focused on a few biological pathways, e.g., aryl hydrocarbon receptor (AhR) or estrogen...
Blackwell, Brett R.; Ankley, Gerald T.; Bradley, Paul M.; Houck, Keith A.; Makarov, Sergei S.; Medvedev, Alexander V.; Swintek, Joe; Villeneuve, Daniel L. Mixed-chemical exposure and predicted effects potential in wadeable southeastern USA streams
Complex chemical mixtures have been widely reported in larger streams but relatively little work has been done to characterize them and assess their potential effects in headwaterstreams. In 2014, the United States Geological Survey (USGS) sampled 54 Piedmont streams over ten weeks and measured 475 unique organic compounds...
Bradley, Paul M.; Journey, Celeste A.; Berninger, Jason P.; Button, Daniel T.; Clark, Jimmy M.; Corsi, Steven R.; DeCicco, Laura A.; Hopkins, Kristina G.; Huffman, Bradley J.; Nakagaki, Naomi; Norman, Julia E.; Nowell, Lisa H.; Qi, Sharon L.; Van Metre, Peter C.; Waite, Ian R.
Pharmaceuticals common in small streams in the U.S.
Human-use pharmaceuticals are frequently present in many small streams, even those not receiving wastewater treatment plant discharges, reports a new study by the U.S. Geological Survey. In some streams, pharmaceuticals were detected at concentrations that could potentially be of concern for fish health.