Using the 384-well plate format, a single zebrafish embryo is tested in each well. This is an example of a 72 hour post fertilization fli1:egfp zebrafish (3 millimeters long) imaged under a fluorescein isothiocyanate (FITC) filter.
Jessica K Leet, PhD
Dr. Jessica Leet is a Research Toxicologist at the Columbia Environmental Research Center.
Her current research is on effects of environmental contaminants on fish, with an emphasis on endocrine disruption during fish development and reproduction. Typically her research involves evaluation of multiple levels of biological organization, including analysis of gene and protein expression, plasma hormones, histology, growth, and reproduction.
Professional Experience
2015-present Research Toxicologist, US Geological Survey, Columbia Environmental Research Center, Columbia MO
2014-2015 Adjunct Faculty, University of South Carolina Aiken, Aiken SC
2013-2015 Postdoctoral Fellow, University of South Carolina, Columbia SC
2013 Postdoctoral Research Assistant, Purdue University, West Lafayette IN
Education and Certifications
Ph.D. Ecotoxicology, Purdue University 2012
M.S. Toxicology and Risk Assessment, University of Tennessee at Chattanooga 2008
B.S. Environmental Studies, University of Central Florida 2006
Science and Products
Prior Exposure to Estrogen Enabled Bass to Better Survive A Bacterial Infection, but With an Energetic Price Tag
Effects of Early Life Stage Exposure of Largemouth Bass to Atrazine or a Model Estrogen (17α-Ethinylestradiol)
Contaminant-related Activities in Support of Client Agencies in the Department of the Interior
Computer-Assisted Sperm Motion Analysis in Measuring Reproductive Effects in Bass
Alternative complement pathway assay data for adult largemouth bass exposed in outdoor ponds to 17alpha-ethinylestradiol or an estrone-atrazine mixture
Motility of sperm from adult largemouth bass pond exposure to 17 alpha-ethinylestradiol or estrone-atrazine mixture (2018)
Water chemistry and fish metrics data for adult largemouth bass exposed in outdoor ponds to 17alpha-ethinylestradiol or an estrone-atrazine mixture
Physiological and molecular endpoints observed in juvenile largemouth bass in response to an estrogen (17α-ethinylestradiol) and subsequently a bacterial challenge (Edwardsiella piscicida) exposure under laboratory conditions.
Effects of early life stage exposure of largemouth bass to atrazine or a model estrogen (17a-ethinylestradiol)
Using the 384-well plate format, a single zebrafish embryo is tested in each well. This is an example of a 72 hour post fertilization fli1:egfp zebrafish (3 millimeters long) imaged under a fluorescein isothiocyanate (FITC) filter.
Molecular Devices ImageXpress† High-Content Imaging System
Molecular Devices ImageXpress† High-Content Imaging System
Molecular Devices ImageXpress† High-Content Imaging System that can generate more than 25,000 images in less than 5 hours of automated image acquisition.
Molecular Devices ImageXpress† High-Content Imaging System that can generate more than 25,000 images in less than 5 hours of automated image acquisition.
This is an example of a 72 hour post fertilization fli1:egfp zebrafish (3 millimeters long) imaged under transmitted light. The same imaging system with was used.
This is an example of a 72 hour post fertilization fli1:egfp zebrafish (3 millimeters long) imaged under transmitted light. The same imaging system with was used.
High-Content Screening Laboratory — Columbia, Missouri. Molecular Devices ImageXpress† High-Content Imaging System
High-Content Screening Laboratory — Columbia, Missouri. Molecular Devices ImageXpress† High-Content Imaging System
The zebrafish developmental cardiovascular toxicity high-content screening assay uses a 384-well plate format to maximize number of treatments and replicates possible on each plate.
The zebrafish developmental cardiovascular toxicity high-content screening assay uses a 384-well plate format to maximize number of treatments and replicates possible on each plate.
Declines in reproductive condition of male largemouth bass (Micropterus salmoides) following seasonal exposure to estrogenic endocrine-disrupting compounds
Exposure to 17α-ethinylestradiol results in differential susceptibility of largemouth bass (Micropterus salmoides) to bacterial infection
Effects of early life stage exposure of largemouth bass to atrazine or a model estrogen (17α-ethinylestradiol)
Factors affecting sampling strategies for design of an effects‐directed analysis for endocrine‐active chemicals
Non-USGS Publications**
**Disclaimer: The views expressed in Non-USGS publications are those of the author and do not represent the views of the USGS, Department of the Interior, or the U.S. Government.
Science and Products
Prior Exposure to Estrogen Enabled Bass to Better Survive A Bacterial Infection, but With an Energetic Price Tag
Effects of Early Life Stage Exposure of Largemouth Bass to Atrazine or a Model Estrogen (17α-Ethinylestradiol)
Contaminant-related Activities in Support of Client Agencies in the Department of the Interior
Computer-Assisted Sperm Motion Analysis in Measuring Reproductive Effects in Bass
Alternative complement pathway assay data for adult largemouth bass exposed in outdoor ponds to 17alpha-ethinylestradiol or an estrone-atrazine mixture
Motility of sperm from adult largemouth bass pond exposure to 17 alpha-ethinylestradiol or estrone-atrazine mixture (2018)
Water chemistry and fish metrics data for adult largemouth bass exposed in outdoor ponds to 17alpha-ethinylestradiol or an estrone-atrazine mixture
Physiological and molecular endpoints observed in juvenile largemouth bass in response to an estrogen (17α-ethinylestradiol) and subsequently a bacterial challenge (Edwardsiella piscicida) exposure under laboratory conditions.
Effects of early life stage exposure of largemouth bass to atrazine or a model estrogen (17a-ethinylestradiol)
Using the 384-well plate format, a single zebrafish embryo is tested in each well. This is an example of a 72 hour post fertilization fli1:egfp zebrafish (3 millimeters long) imaged under a fluorescein isothiocyanate (FITC) filter.
Using the 384-well plate format, a single zebrafish embryo is tested in each well. This is an example of a 72 hour post fertilization fli1:egfp zebrafish (3 millimeters long) imaged under a fluorescein isothiocyanate (FITC) filter.
Molecular Devices ImageXpress† High-Content Imaging System
Molecular Devices ImageXpress† High-Content Imaging System
Molecular Devices ImageXpress† High-Content Imaging System that can generate more than 25,000 images in less than 5 hours of automated image acquisition.
Molecular Devices ImageXpress† High-Content Imaging System that can generate more than 25,000 images in less than 5 hours of automated image acquisition.
This is an example of a 72 hour post fertilization fli1:egfp zebrafish (3 millimeters long) imaged under transmitted light. The same imaging system with was used.
This is an example of a 72 hour post fertilization fli1:egfp zebrafish (3 millimeters long) imaged under transmitted light. The same imaging system with was used.
High-Content Screening Laboratory — Columbia, Missouri. Molecular Devices ImageXpress† High-Content Imaging System
High-Content Screening Laboratory — Columbia, Missouri. Molecular Devices ImageXpress† High-Content Imaging System
The zebrafish developmental cardiovascular toxicity high-content screening assay uses a 384-well plate format to maximize number of treatments and replicates possible on each plate.
The zebrafish developmental cardiovascular toxicity high-content screening assay uses a 384-well plate format to maximize number of treatments and replicates possible on each plate.
Declines in reproductive condition of male largemouth bass (Micropterus salmoides) following seasonal exposure to estrogenic endocrine-disrupting compounds
Exposure to 17α-ethinylestradiol results in differential susceptibility of largemouth bass (Micropterus salmoides) to bacterial infection
Effects of early life stage exposure of largemouth bass to atrazine or a model estrogen (17α-ethinylestradiol)
Factors affecting sampling strategies for design of an effects‐directed analysis for endocrine‐active chemicals
Non-USGS Publications**
**Disclaimer: The views expressed in Non-USGS publications are those of the author and do not represent the views of the USGS, Department of the Interior, or the U.S. Government.