Avian Influenza Spread, Prevalence and Persistence
USGS researchers seek to understand the factors influencing the spread and persistence of avian influenza viruses on the landscape. This research also addresses how novel strains of highly pathogenic avian influenza are impacting a larger number and diversity of host species, including waterfowl, shorebirds, raptors and other birds.
What is the issue?
Avian influenza has had severe effects on wild birds, domestic poultry and, increasingly, mammals since the first detection of highly pathogenic avian influenza virus (HPAI) H5N1 clade 2.3.4.4b in North America in late 2021. What differentiates the currently circulating strain of HPAI from previous strains is the magnitude of the effect on migratory wild birds. This strain of avian influenza has resulted in tens of thousands of reported, suspected and confirmed infections in wild birds, including infections in a diversity of species previously not known to have been affected by HPAI. In addition, little is known regarding how this particular strain may persist in water and within bird hosts, both of which could affect the magnitude and duration of avian influenza outbreaks.
What is at stake?
Further increases in avian influenza virus transmission have the potential for major economic damage, impacts on food security and mortality events among domestic animals and wild birds, including populations and species of conservation concern.
What is our approach?
Surveillance efforts for avian influenza usually focus on sampling waterfowl, especially dabbling ducks like mallards, which are known to spread the virus to other animals and into new areas. However, this approach is insufficient to understand the HPAI strain now circulating in North America because wild birds other than waterfowl as well as the physical environment may serve as additional natural reservoirs for the virus.
To fill this gap, USGS is collaborating with partners to:
- Assess what viral strains are circulating in wild waterfowl and how viruses are spreading and evolving across the landscape. Learn more.
- Assess which non-traditional host species have been impacted and which have mounted antibody responses. Learn more.
- Increase understanding of the species and environmental conditions that facilitate persistence of the virus on the landscape across seasons and movement of the virus within and between migratory bird flyways. Learn more.
Compare laboratory experiments and experimental challenge studies to assess how field-based results relate to information obtained through laboratory models.
What are the benefits?
North America is facing a future with the potential for additional avian influenza outbreaks affecting large numbers of wildlife, captive species, and poultry. Gaining a better understanding of the spread, prevalence and persistence of highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b will aid natural resource managers and poultry producers in their surveillance of and response to the virus. Results from this research will also provide better inputs for avian influenza transmission risk models.
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Understanding Circulating Avian Influenza Viruses and How They Spread
Pathogens in the Aquatic Environment – Waterfowl, Avian Influenza
USGS Wild Bird Avian Influenza Program – Studies from Endemic Regions of Eurasia
Understanding Avian Influenza Exposure and Antibodies in Understudied Species
Using Telemetry to Understand Overlap in Habitat Use Between Waterfowl and Agricultural Birds in North America
Avian Influenza Dynamics in the Chesapeake Bay Region
Tracking Domestic Ducks through the Market Chain in China via Telemetry
Avian influenza infection and antibodies not identified in eastern wild turkeys (Meleagris gallopavo silvestris) sampled on the Delmarva Peninsula Avian influenza infection and antibodies not identified in eastern wild turkeys (Meleagris gallopavo silvestris) sampled on the Delmarva Peninsula
Antibodies to influenza A virus in Lesser (Aythya affinis) and Greater Scaup (Aythya marila) in the USA Antibodies to influenza A virus in Lesser (Aythya affinis) and Greater Scaup (Aythya marila) in the USA
Mitigating risk: Predicting H5N1 avian influenza spread with an empirical model of bird movement Mitigating risk: Predicting H5N1 avian influenza spread with an empirical model of bird movement
Functional traits explain waterbirds’ host status, subtype richness, and community-level infection risk for avian influenza Functional traits explain waterbirds’ host status, subtype richness, and community-level infection risk for avian influenza
Avian influenza antibody prevalence increases with mercury contamination in wild waterfowl Avian influenza antibody prevalence increases with mercury contamination in wild waterfowl
Maintenance and dissemination of avian-origin influenza A virus within the northern Atlantic Flyway of North America Maintenance and dissemination of avian-origin influenza A virus within the northern Atlantic Flyway of North America
Do contrasting patterns of migration movements and disease outbreaks between congeneric waterfowl species reflect differing immunity? Do contrasting patterns of migration movements and disease outbreaks between congeneric waterfowl species reflect differing immunity?
Crossroads of highly pathogenic H5N1: overlap between wild and domestic birds in the Black Sea-Mediterranean impacts global transmission Crossroads of highly pathogenic H5N1: overlap between wild and domestic birds in the Black Sea-Mediterranean impacts global transmission
Influenza A viruses remain infectious for more than seven months in northern wetlands of North America Influenza A viruses remain infectious for more than seven months in northern wetlands of North America
Limited detection of antibodies to clade 2.3.4.4 A/Goose/Guangdong/1/1996 lineage highly pathogenic H5 avian influenza virus in North American waterfowl Limited detection of antibodies to clade 2.3.4.4 A/Goose/Guangdong/1/1996 lineage highly pathogenic H5 avian influenza virus in North American waterfowl
The impact of surveillance and control on highly pathogenic avian influenza outbreaks in poultry in Dhaka division, Bangladesh The impact of surveillance and control on highly pathogenic avian influenza outbreaks in poultry in Dhaka division, Bangladesh
Surveillance for highly pathogenic influenza A viruses in California during 2014–2015 provides insights into viral evolutionary pathways and the spatiotemporal extent of viruses in the Pacific Americas Flyway Surveillance for highly pathogenic influenza A viruses in California during 2014–2015 provides insights into viral evolutionary pathways and the spatiotemporal extent of viruses in the Pacific Americas Flyway
USGS researchers seek to understand the factors influencing the spread and persistence of avian influenza viruses on the landscape. This research also addresses how novel strains of highly pathogenic avian influenza are impacting a larger number and diversity of host species, including waterfowl, shorebirds, raptors and other birds.
What is the issue?
Avian influenza has had severe effects on wild birds, domestic poultry and, increasingly, mammals since the first detection of highly pathogenic avian influenza virus (HPAI) H5N1 clade 2.3.4.4b in North America in late 2021. What differentiates the currently circulating strain of HPAI from previous strains is the magnitude of the effect on migratory wild birds. This strain of avian influenza has resulted in tens of thousands of reported, suspected and confirmed infections in wild birds, including infections in a diversity of species previously not known to have been affected by HPAI. In addition, little is known regarding how this particular strain may persist in water and within bird hosts, both of which could affect the magnitude and duration of avian influenza outbreaks.
What is at stake?
Further increases in avian influenza virus transmission have the potential for major economic damage, impacts on food security and mortality events among domestic animals and wild birds, including populations and species of conservation concern.
What is our approach?
Surveillance efforts for avian influenza usually focus on sampling waterfowl, especially dabbling ducks like mallards, which are known to spread the virus to other animals and into new areas. However, this approach is insufficient to understand the HPAI strain now circulating in North America because wild birds other than waterfowl as well as the physical environment may serve as additional natural reservoirs for the virus.
To fill this gap, USGS is collaborating with partners to:
- Assess what viral strains are circulating in wild waterfowl and how viruses are spreading and evolving across the landscape. Learn more.
- Assess which non-traditional host species have been impacted and which have mounted antibody responses. Learn more.
- Increase understanding of the species and environmental conditions that facilitate persistence of the virus on the landscape across seasons and movement of the virus within and between migratory bird flyways. Learn more.
Compare laboratory experiments and experimental challenge studies to assess how field-based results relate to information obtained through laboratory models.
What are the benefits?
North America is facing a future with the potential for additional avian influenza outbreaks affecting large numbers of wildlife, captive species, and poultry. Gaining a better understanding of the spread, prevalence and persistence of highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b will aid natural resource managers and poultry producers in their surveillance of and response to the virus. Results from this research will also provide better inputs for avian influenza transmission risk models.
<< Back to Avian Influenza Research at EESC