Endocrine Disruption

U.S. Geological Survey (USGS) and academic scientists partnered to identify challenges and provide considerations for future scientific study designs to advance our understanding of the often subtle sublethal effects of contaminants on individuals, populations, communities, and entire aquatic food webs.

Scientists determined what happens to the neonicotinoid insecticide, imidacloprid, on coated wheat seeds once ingested by Japanese quail (Coturnix japonica)—a model species for free-range, seed-eating, upland game birds. Imidacloprid was found to be rapidly adsorbed, metabolized, and excreted, and resulted in no overt signs of toxicity during a controlled laboratory study.

Science from the U.S. Geological Survey (USGS) and other entities has shown that a mixture of natural and synthetic estrogens and other similar chemicals are discharged from wastewater treatment plants (WWTPs) to streams and rivers.

Our specialized teams of scientists are working in our laboratories and at field sites around the Great Lakes in collaboration with other federal and state resource agencies to document the prevalence of skin and liver tumors in fish. Tumor prevalence in white suckers ( Catostomus commersonii), a fish harvested as a food source by local communities, is related to the degree of urbanization in the...

The Bioactive Chemicals Research Laboratory applies a collaborative transdisciplinary approach to conduct research to minimize the risk to human and aquatic organism health from exposure to contaminants in water supplies.

About the Research The Environmental Chemistry Laboratory Core Technology Team (CTT) as part of the Environmental Health Program develops and applies innovative methods of sampling and analysis to answer critical questions about the occurrence, distribution, fate and transport, and biological exposure of chemical in all environmental matrices (water, air, tissues, sediments, and others).

The Fishing, Hunting, and Subsistence Living Integrated Science Team focuses on contaminant and pathogen exposures in the environment that could impact the presence and vitality of fish and wildlife populations that drive commercial, recreational and subsistence activities such as hunting and fishing. If actual risks are identified this project will inform how to economically and effectively...

Scientists optimized existing endocrine active chemical screening tests to improve their precision, accuracy, and ability to screen more samples in a shorter time-frame. The optimization was done to more rapidly obtain results from the bioassays so that research on the risks of endocrine active chemical exposure can proceed more rapidly.

The Chesapeake Bay is the largest estuary in the United States and provides critical resources to fish, wildlife and people. For more than a decade, recreational fish species have been plagued with skin lesions and intersex conditions (the presence of male and female sex characteristics in the same fish) that biologists attributed to exposures to endocrine disrupting chemicals (EDCs)...

A new study highlights the complexity of chemical mixtures in streams and advances the understanding of wildlife and human exposure to complex chemical mixtures.

Short-term laboratory exposure of adult fathead minnows to the human contraceptive progestin, gestodene (GES), at environmentally relevant concentrations induced rapid and negative effects on reproductive health and suggests that wild fish may be similarly affected.

Scientists conducted laboratory experiments on levonorgestrel (a synthetic progestin) and observed differential effects to males (reproductive behavior) and females (masculinization) of eastern mosquitofish ( Gambusia holbrooki).