Donald Tillitt, PhD (Former Employee)

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February 8, 2019

Thiamine (Vitamin B1) Deficiency in Fish and Wildlife

In the last few decades, thiamine deficiency has been observed in fish and wildlife in the Great Lakes, Alaska, Sweden and several other areas in North America and Europe. Thiamine is an essential vitamin needed for cell function. Thiamine deficiency has been linked to neurological disorders, immunosuppression, and lower reproductive viability. These disorders potentially reduce populations of...

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Ecosystems Mission Area, Species Management Research Program, Columbia Environmental Research Center

Thiamine (Vitamin B1) Deficiency in Fish and Wildlife

February 8, 2019

Thiamine (Vitamin B1) Deficiency in Fish and Wildlife

In the last few decades, thiamine deficiency has been observed in fish and wildlife in the Great Lakes, Alaska, Sweden and several other areas in North America and Europe. Thiamine is an essential vitamin needed for cell function. Thiamine deficiency has been linked to neurological disorders, immunosuppression, and lower reproductive viability. These disorders potentially reduce populations of...

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January 1, 2000

An in vivo model fish system to test chemical effects on sexual differentiation and development: exposure to ethinyl estradiol An in vivo model fish system to test chemical effects on sexual differentiation and development: exposure to ethinyl estradiol

A model system was characterized which may be used as an in vivo screen for effects of chemicals or environmental mixtures on sexual differentiation and development of reproductive organs and gametes. We evaluated the effects of a model environmental estrogen, ethinyl estradiol (EE2), on the d-rR strain of medaka, Oryzias latipes, using a nano-injection exposure. Gonad histopathology...

Authors

Diana M. Papoulias, Douglas B. Noltie, Donald E. Tillitt

By

Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 2000

Toxic responses of medaka, D-rR strain, to polychlorinatednaphthalene mixtures after embryonic exposure by in ovo nanoinjection: A partial life-cycle assessment Toxic responses of medaka, D-rR strain, to polychlorinatednaphthalene mixtures after embryonic exposure by in ovo nanoinjection: A partial life-cycle assessment

Polychlorinated naphthalenes (PCNs) are organic compounds with some chemical properties and uses similar to polychlorinated biphenyls. Polychlorinated naphthalenes have been detected in biota from certain aquatic environments. The toxicities of several PCN technical mixtures (Halowax) to medaka (Oryzias latipes) were determined by use of an embryo nanoinjection method. Medaka eggs (early...

Authors

Sergio A. Villalobos, Diana M. Papoulias, John C. Meadows, Alan L. Blankenship, Stephanie D. Pastva, Kurunthachalam Kannan, D.E. Hinton, Donald E. Tillitt, John P. Giesy

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Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 2000

Comparison of an enzyme-linked immunosorbent assay (ELISA) to gas chromatography (GC) - measurement of polychlorinated biphenyls (PCBs) in selected US fish extracts Comparison of an enzyme-linked immunosorbent assay (ELISA) to gas chromatography (GC) - measurement of polychlorinated biphenyls (PCBs) in selected US fish extracts

The analysis of PCBs in fish tissues by immunoassay methods was evaluated using fish collected from a US monitoring program, the National Contaminant Biomonitoring Program of the US Department of Interior, Fish and Wildlife Service. Selected composite whole fish samples, which represented widely varying concentrations and sources of PCBs, were extracted and subjected to congener PCB...

Authors

J.L. Zajicek, D. E. Tillitt, T.R. Schwartz, C. J. Schmitt, R.O. Harrison

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Ecosystems Mission Area, Columbia Environmental Research Center

November 1, 1999

Polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents in tree swallows from the upper Hudson River, New York State, USA Polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents in tree swallows from the upper Hudson River, New York State, USA

The upper Hudson River of New York State, USA, is contaminated with polychlorinated biphenyls (PCBs) as a result of industrial discharges throughout the latter half of this century. In 1994 and 1995, we monitored the transfer of PCBs from aquatic sediments to a terrestrial wildlife community using the tree swallow (Tachycineta bicolor) as a model organism. Tree swallow eggs and nestlings...

Authors

Anne L. Secord, John P. McCarty, Kathy R. Echols, John C. Meadows, Robert W. Gale, Donald E. Tillitt

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Ecosystems Mission Area, Columbia Environmental Research Center

July 15, 1999

Embryotoxicity of Great Lakes lake trout extracts to developing rainbow trout Embryotoxicity of Great Lakes lake trout extracts to developing rainbow trout

Planar halogenated hydrocarbons (PHHs), such as polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls are present in aquatic systems, and are known to produce adverse effects in fish. This study investigated the embryotoxicity of PHH mixtures through the nanoinjection of environmental extracts into newly fertilized eggs from two strains of rainbow trout. Organic extracts were...

Authors

Peggy J. Wright, Donald E. Tillitt

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Ecosystems Mission Area, Columbia Environmental Research Center

July 15, 1999

Workshop introduction Workshop introduction

No abstract available.

Authors

Ellen Mihaich, Jay W. Gooch, P.L deFur, W.H. Benson, C. Tyler, L. Birnbaum, R.T. Di Giulio, D. E. Tillitt

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Ecosystems Mission Area, Columbia Environmental Research Center

June 15, 1999

Workshop summary, conclusions and recommendations Workshop summary, conclusions and recommendations

No abstract available.

Authors

W.H. Benson, R.T. Di Giulio, D. E. Tillitt, L. Birnbaum, P.L deFur, Jay W. Gooch, Ellen Mihaich, C. Tyler

By

Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 1999

Factors associated with temporal variation in EMS: Research task report on early mortality syndrome workshop Factors associated with temporal variation in EMS: Research task report on early mortality syndrome workshop

No abstract available at this time

Authors

J. Fitzsimons, S.B. Brown, D. C. Honeyfield, D. E. Tillitt, J. Zajicek, J.G. Hnath

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Ecosystems Mission Area, Eastern Ecological Science Center

January 1, 1999

Biomonitoring of Environmental Status and Trends (BEST) Program: Field Procedures for Assessing the Exposure of Fish to Environmental Contaminants Biomonitoring of Environmental Status and Trends (BEST) Program: Field Procedures for Assessing the Exposure of Fish to Environmental Contaminants

This document describes procedures used to collect information, tissues, and fluids for documenting the exposure of fish to environmental contaminants. For the procedures described here, fish are captured (preferably by electrofishing) and held alive until processing (generally

Authors

Christopher J. Schmitt, Vicki Blazer, Gail M. Dethloff, Donald E. Tillitt, Timothy S. Gross, Wade L. Bryant, L. Rod DeWeese, Stephen B. Smith, Ronald W. Goede, Timothy M. Bartish, Timothy J. Kubiak

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Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 1999

Review of a natural thiamine deficiency causing reproductive failure in feral salmonid species of the Great Lakes Review of a natural thiamine deficiency causing reproductive failure in feral salmonid species of the Great Lakes

No abstract available at this time

Authors

D. C. Honeyfield, D. E. Tillitt, S.B. Brown, J.D. Fitzsimons

By

Ecosystems Mission Area, Eastern Ecological Science Center

January 1, 1999

The toxic equivalents approach for fish and wildlife The toxic equivalents approach for fish and wildlife

No abstract available.

Authors

Donald E. Tillitt

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Ecosystems Mission Area, Columbia Environmental Research Center

January 1, 1999

Cytochrome P4501A induction, benzo[a]pyrene metabolism, and nucleotide adduct formation in fish hepatoma cells: Effect of preexposure to 3,3',4,4',5-pentachlorobiphenyl Cytochrome P4501A induction, benzo[a]pyrene metabolism, and nucleotide adduct formation in fish hepatoma cells: Effect of preexposure to 3,3',4,4',5-pentachlorobiphenyl

In PLHC-1 hepatoma cells, benzo[a]pyrene (B[a]P) caused a maximum induction of cytochrome P4501A (CYP1A) activity, measured as ethoxyresorufin O-deethylation (EROD), after 4 to 8 h of exposure, depending on the B[a]P concentration. The decline of EROD activity at longer exposure times was probably caused by the rapid metabolism of B[a]P in this system (57% metabolism within 4 h...

Authors

J.M.W. Smeets, A. Voormolen, D. E. Tillitt, J.M. Everaarts, W. Seinen, Vanden Berg

By

Ecosystems Mission Area, Columbia Environmental Research Center

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