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Michael Focazio, PhD (Former Employee)

Science and Products

Filter Total Items: 68
Primary leukocytes have been isolated from experimental fish to evaluate functional immune responses

Functional and Molecular Bioassay Core Technology Team

About the Research The Functional and Molecular Bioassay Core Technology Team (CTT) as part of the Environmental Health Program utilizes reporter assays, quantitative gene expression analyses, and high-throughput sequencing methods to produce functional endpoints across a broad scope of environmental topics and sample matrices.
By
Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, Eastern Ecological Science Center
Functional and Molecular Bioassay Core Technology Team

Functional and Molecular Bioassay Core Technology Team

About the Research The Functional and Molecular Bioassay Core Technology Team (CTT) as part of the Environmental Health Program utilizes reporter assays, quantitative gene expression analyses, and high-throughput sequencing methods to produce functional endpoints across a broad scope of environmental topics and sample matrices.
Learn More
Instrumentation set up in a valley near a mountain.

Hydrogeophysics Core Technology Team

About the Research. The Hydrogeophysics Core Technology Team (CTT) as part of the Environmental Health Program specializes in locating and quantifying exchanges of groundwater and surface water, along with characterizing geologic structure and mapping hydrologic connectivity across varied landscapes.
By
Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology
Hydrogeophysics Core Technology Team

Hydrogeophysics Core Technology Team

About the Research. The Hydrogeophysics Core Technology Team (CTT) as part of the Environmental Health Program specializes in locating and quantifying exchanges of groundwater and surface water, along with characterizing geologic structure and mapping hydrologic connectivity across varied landscapes.
Learn More
Microscopic video imaging is used for computerized analysis of sperm motility parameters

Photomicroscopy and Flow Cytometry Core Technology Team

About the Research The Photomicroscopy and Flow Cytometry Core Technology Team (CTT) as part of the Environmental Health Program works to develop and apply biomarkers to evaluate the potential impacts of environmental contaminants at cellular and molecular levels. Because molecular and biochemical responses of cells are preceded by chemical changes in nuclei, cytoplasm, membranes, and...
By
Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology
Photomicroscopy and Flow Cytometry Core Technology Team

Photomicroscopy and Flow Cytometry Core Technology Team

About the Research The Photomicroscopy and Flow Cytometry Core Technology Team (CTT) as part of the Environmental Health Program works to develop and apply biomarkers to evaluate the potential impacts of environmental contaminants at cellular and molecular levels. Because molecular and biochemical responses of cells are preceded by chemical changes in nuclei, cytoplasm, membranes, and...
Learn More
Attribution of storm-weighted potential contaminant hazard ranks to sampling locations

Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
By
Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, Chesapeake Bay Activities
Geospatial Analyses and Applications Core Technology Team

Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
Learn More
Attribution of storm-weighted potential contaminant hazard ranks to sampling locations

Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
By
Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, Chesapeake Bay Activities
Geospatial Analyses and Applications Core Technology Team

Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
Learn More
Attribution of storm-weighted potential contaminant hazard ranks to sampling locations

Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
By
Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, Chesapeake Bay Activities
Geospatial Analyses and Applications Core Technology Team

Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
Learn More
No Result Found
Filter Total Items: 67

Bottled water contaminant exposures and potential human effects Bottled water contaminant exposures and potential human effects

Bottled water (BW) consumption in the United States and globally has increased amidst heightened concern about environmental contaminant exposures and health risks in drinking water supplies, despite a paucity of directly comparable, environmentally-relevant contaminant exposure data for BW. This study provides insight into exposures and cumulative risks to human health from inorganic...
Authors
Paul M. Bradley, Kristin M. Romanok, Kelly L. Smalling, Michael J. Focazio, Nicola Evans, Suzanne C. Fitzpatrick, Carrie E. Givens, Stephanie E. Gordon, James L. Gray, Emily M. Green, Dale W. Griffin, Michelle L. Hladik, Leslie K. Kanagy, John T. Lisle, Keith A. Loftin, R. Blaine McCleskey, Elizabeth Medlock-Kakaley, Ana Navas-Acien, David A. Roth, Paul F. South, Christopher P. Weis
By
Water Resources Mission Area, Central Plains Water Science Center, California Water Science Center, New Jersey Water Science Center, South Atlantic Water Science Center (SAWSC), St. Petersburg Coastal and Marine Science Center, Upper Midwest Water Science Center

Tapwater exposures, effects potential, and residential risk management in Northern Plains Nations Tapwater exposures, effects potential, and residential risk management in Northern Plains Nations

In the United States (US), private-supply tapwater (TW) is rarely monitored. This data gap undermines individual/community risk-management decision-making, leading to an increased probability of unrecognized contaminant exposures in rural and remote locations that rely on private wells. We assessed point-of-use (POU) TW in three northern plains Tribal Nations, where ongoing TW arsenic...
Authors
Paul M. Bradley, Kristin M. Romanok, Kelly L. Smalling, Michael J. Focazio, Robert Charboneau, Christine Marie George, Ana Navas-Acien, Marcia O’Leary, Reno Red Cloud, Tracy Zacher, Sara E. Breitmeyer, Mary C. Cardon, Christa K. Cuny, Guthrie Ducheneaux, Kendra Enright, Nicola Evans, James L. Gray, David E. Harvey, Michelle L. Hladik, Leslie K. Kanagy, Keith A. Loftin, R. Blaine McCleskey, Elizabeth Medlock-Kakaley, Shannon M. Meppelink, Joshua F. Valder, Christopher P. Weis
By
Water Resources Mission Area, South Atlantic Water Science Center (SAWSC)

Rapid implementation of high-frequency wastewater surveillance of SARS-CoV-2 Rapid implementation of high-frequency wastewater surveillance of SARS-CoV-2

There have been over 507 million cases of COVID-19, the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in 6 million deaths globally. Wastewater surveillance has emerged as a valuable tool in understanding SARS-CoV-2 burden in communities. The National Wastewater Surveillance System (NWSS) partnered with the United States Geological Survey...
Authors
Meghan M. Holst, John Person, Wiley Jennings, Rory M. Welsh, Michael J. Focazio, Paul M. Bradley, W. Bane Schill, Amy E. Kirby, Zachary A. Marsh
By
Ecosystems Mission Area, Water Resources Mission Area, Eastern Ecological Science Center, South Atlantic Water Science Center (SAWSC)

Arsenic in private well water and birth outcomes in the United States Arsenic in private well water and birth outcomes in the United States

Background Prenatal exposure to drinking water with arsenic concentrations >50 μg/L is associated with adverse birth outcomes, with inconclusive evidence for concentrations ≤50 μg/L. In a collaborative effort by public health experts, hydrologists, and geologists, we used published machine learning model estimates to characterize arsenic concentrations in private wells—federally...
Authors
Catherine Bulka, Molly Scannell Bryan, Melissa A. Lombard, Scott Bartell, Daniel K. Jones, Paul M. Bradley, Veronica Vieira, Debra Silverman, Michael J. Focazio, Patricia Toccalino, Johnni Daniel, Lorraine C. Backer, Joseph D. Ayotte, Matthew O. Gribble, Maria Argos
By
Water Resources Mission Area, John Wesley Powell Center for Analysis and Synthesis, New England Water Science Center, South Atlantic Water Science Center (SAWSC)

Integrated science for the study of perfluoroalkyl and polyfluoroalkyl substances (PFAS) in the environment—A strategic science vision for the U.S. Geological Survey Integrated science for the study of perfluoroalkyl and polyfluoroalkyl substances (PFAS) in the environment—A strategic science vision for the U.S. Geological Survey

Concerns related to perfluoroalkyl and polyfluoroalkyl substances (PFAS) in sources of drinking water and in natural and engineered environments have captured national attention over the last few decades. This report provides an overview of the science gaps that exist in the fields of study related to PFAS that are relevant to the U.S. Geological Survey mission and identifies...
Authors
Andrea K. Tokranov, Paul M. Bradley, Michael J. Focazio, Douglas B. Kent, Denis R. LeBlanc, Jeff W. McCoy, Kelly L. Smalling, Jeffery A. Steevens, Patricia L. Toccalino
By
Ecosystems Mission Area, Water Resources Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, Columbia Environmental Research Center, New England Water Science Center, New Jersey Water Science Center, South Atlantic Water Science Center (SAWSC)

Pilot-scale expanded assessment of inorganic and organic tapwater exposures and predicted effects in Puerto Rico, USA Pilot-scale expanded assessment of inorganic and organic tapwater exposures and predicted effects in Puerto Rico, USA

A pilot-scale expanded target assessment of mixtures of inorganic and organic contaminants in point-of-consumption drinking water (tapwater, TW) was conducted in Puerto Rico (PR) to continue to inform TW exposures and corresponding estimations of cumulative human-health risks across the US. In August 2018, a spatial synoptic pilot assessment of than 524 organic, 37 inorganic, and select
Authors
Paul M. Bradley, Ingrid Y. Padilla, Kristin M. Romanok, Kelly Smalling, Michael J. Focazio, Sara E. Breitmeyer, Mary C. Cardon, Justin M. Conley, Nicola Evans, Carrie E. Givens, James L. Gray, L. Earl Gray, Phillip C. Hartig, Michelle L. Hladik, Christopher P. Higgins, Luke R. Iwanowicz, Rachael F. Lane, Keith A. Loftin, R. Blaine McCleskey, Carrie A. McDonough, Elizabeth Medlock-Kakaley, Shannon M. Meppelink, Christopher P. Weis, Vickie S. Wilson
By
Ecosystems Mission Area, Water Resources Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, South Atlantic Water Science Center (SAWSC), National Water Quality Laboratory

Science and Products

Filter Total Items: 68
Primary leukocytes have been isolated from experimental fish to evaluate functional immune responses

Functional and Molecular Bioassay Core Technology Team

About the Research The Functional and Molecular Bioassay Core Technology Team (CTT) as part of the Environmental Health Program utilizes reporter assays, quantitative gene expression analyses, and high-throughput sequencing methods to produce functional endpoints across a broad scope of environmental topics and sample matrices.
By
Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, Eastern Ecological Science Center
Functional and Molecular Bioassay Core Technology Team

Functional and Molecular Bioassay Core Technology Team

About the Research The Functional and Molecular Bioassay Core Technology Team (CTT) as part of the Environmental Health Program utilizes reporter assays, quantitative gene expression analyses, and high-throughput sequencing methods to produce functional endpoints across a broad scope of environmental topics and sample matrices.
Learn More
Instrumentation set up in a valley near a mountain.

Hydrogeophysics Core Technology Team

About the Research. The Hydrogeophysics Core Technology Team (CTT) as part of the Environmental Health Program specializes in locating and quantifying exchanges of groundwater and surface water, along with characterizing geologic structure and mapping hydrologic connectivity across varied landscapes.
By
Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology
Hydrogeophysics Core Technology Team

Hydrogeophysics Core Technology Team

About the Research. The Hydrogeophysics Core Technology Team (CTT) as part of the Environmental Health Program specializes in locating and quantifying exchanges of groundwater and surface water, along with characterizing geologic structure and mapping hydrologic connectivity across varied landscapes.
Learn More
Microscopic video imaging is used for computerized analysis of sperm motility parameters

Photomicroscopy and Flow Cytometry Core Technology Team

About the Research The Photomicroscopy and Flow Cytometry Core Technology Team (CTT) as part of the Environmental Health Program works to develop and apply biomarkers to evaluate the potential impacts of environmental contaminants at cellular and molecular levels. Because molecular and biochemical responses of cells are preceded by chemical changes in nuclei, cytoplasm, membranes, and...
By
Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology
Photomicroscopy and Flow Cytometry Core Technology Team

Photomicroscopy and Flow Cytometry Core Technology Team

About the Research The Photomicroscopy and Flow Cytometry Core Technology Team (CTT) as part of the Environmental Health Program works to develop and apply biomarkers to evaluate the potential impacts of environmental contaminants at cellular and molecular levels. Because molecular and biochemical responses of cells are preceded by chemical changes in nuclei, cytoplasm, membranes, and...
Learn More
Attribution of storm-weighted potential contaminant hazard ranks to sampling locations

Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
By
Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, Chesapeake Bay Activities
Geospatial Analyses and Applications Core Technology Team

Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
Learn More
Attribution of storm-weighted potential contaminant hazard ranks to sampling locations

Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
By
Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, Chesapeake Bay Activities
Geospatial Analyses and Applications Core Technology Team

Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
Learn More
Attribution of storm-weighted potential contaminant hazard ranks to sampling locations

Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
By
Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, Chesapeake Bay Activities
Geospatial Analyses and Applications Core Technology Team

Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
Learn More
No Result Found
Filter Total Items: 67

Bottled water contaminant exposures and potential human effects Bottled water contaminant exposures and potential human effects

Bottled water (BW) consumption in the United States and globally has increased amidst heightened concern about environmental contaminant exposures and health risks in drinking water supplies, despite a paucity of directly comparable, environmentally-relevant contaminant exposure data for BW. This study provides insight into exposures and cumulative risks to human health from inorganic...
Authors
Paul M. Bradley, Kristin M. Romanok, Kelly L. Smalling, Michael J. Focazio, Nicola Evans, Suzanne C. Fitzpatrick, Carrie E. Givens, Stephanie E. Gordon, James L. Gray, Emily M. Green, Dale W. Griffin, Michelle L. Hladik, Leslie K. Kanagy, John T. Lisle, Keith A. Loftin, R. Blaine McCleskey, Elizabeth Medlock-Kakaley, Ana Navas-Acien, David A. Roth, Paul F. South, Christopher P. Weis
By
Water Resources Mission Area, Central Plains Water Science Center, California Water Science Center, New Jersey Water Science Center, South Atlantic Water Science Center (SAWSC), St. Petersburg Coastal and Marine Science Center, Upper Midwest Water Science Center

Tapwater exposures, effects potential, and residential risk management in Northern Plains Nations Tapwater exposures, effects potential, and residential risk management in Northern Plains Nations

In the United States (US), private-supply tapwater (TW) is rarely monitored. This data gap undermines individual/community risk-management decision-making, leading to an increased probability of unrecognized contaminant exposures in rural and remote locations that rely on private wells. We assessed point-of-use (POU) TW in three northern plains Tribal Nations, where ongoing TW arsenic...
Authors
Paul M. Bradley, Kristin M. Romanok, Kelly L. Smalling, Michael J. Focazio, Robert Charboneau, Christine Marie George, Ana Navas-Acien, Marcia O’Leary, Reno Red Cloud, Tracy Zacher, Sara E. Breitmeyer, Mary C. Cardon, Christa K. Cuny, Guthrie Ducheneaux, Kendra Enright, Nicola Evans, James L. Gray, David E. Harvey, Michelle L. Hladik, Leslie K. Kanagy, Keith A. Loftin, R. Blaine McCleskey, Elizabeth Medlock-Kakaley, Shannon M. Meppelink, Joshua F. Valder, Christopher P. Weis
By
Water Resources Mission Area, South Atlantic Water Science Center (SAWSC)

Rapid implementation of high-frequency wastewater surveillance of SARS-CoV-2 Rapid implementation of high-frequency wastewater surveillance of SARS-CoV-2

There have been over 507 million cases of COVID-19, the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in 6 million deaths globally. Wastewater surveillance has emerged as a valuable tool in understanding SARS-CoV-2 burden in communities. The National Wastewater Surveillance System (NWSS) partnered with the United States Geological Survey...
Authors
Meghan M. Holst, John Person, Wiley Jennings, Rory M. Welsh, Michael J. Focazio, Paul M. Bradley, W. Bane Schill, Amy E. Kirby, Zachary A. Marsh
By
Ecosystems Mission Area, Water Resources Mission Area, Eastern Ecological Science Center, South Atlantic Water Science Center (SAWSC)

Arsenic in private well water and birth outcomes in the United States Arsenic in private well water and birth outcomes in the United States

Background Prenatal exposure to drinking water with arsenic concentrations >50 μg/L is associated with adverse birth outcomes, with inconclusive evidence for concentrations ≤50 μg/L. In a collaborative effort by public health experts, hydrologists, and geologists, we used published machine learning model estimates to characterize arsenic concentrations in private wells—federally...
Authors
Catherine Bulka, Molly Scannell Bryan, Melissa A. Lombard, Scott Bartell, Daniel K. Jones, Paul M. Bradley, Veronica Vieira, Debra Silverman, Michael J. Focazio, Patricia Toccalino, Johnni Daniel, Lorraine C. Backer, Joseph D. Ayotte, Matthew O. Gribble, Maria Argos
By
Water Resources Mission Area, John Wesley Powell Center for Analysis and Synthesis, New England Water Science Center, South Atlantic Water Science Center (SAWSC)

Integrated science for the study of perfluoroalkyl and polyfluoroalkyl substances (PFAS) in the environment—A strategic science vision for the U.S. Geological Survey Integrated science for the study of perfluoroalkyl and polyfluoroalkyl substances (PFAS) in the environment—A strategic science vision for the U.S. Geological Survey

Concerns related to perfluoroalkyl and polyfluoroalkyl substances (PFAS) in sources of drinking water and in natural and engineered environments have captured national attention over the last few decades. This report provides an overview of the science gaps that exist in the fields of study related to PFAS that are relevant to the U.S. Geological Survey mission and identifies...
Authors
Andrea K. Tokranov, Paul M. Bradley, Michael J. Focazio, Douglas B. Kent, Denis R. LeBlanc, Jeff W. McCoy, Kelly L. Smalling, Jeffery A. Steevens, Patricia L. Toccalino
By
Ecosystems Mission Area, Water Resources Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, Columbia Environmental Research Center, New England Water Science Center, New Jersey Water Science Center, South Atlantic Water Science Center (SAWSC)

Pilot-scale expanded assessment of inorganic and organic tapwater exposures and predicted effects in Puerto Rico, USA Pilot-scale expanded assessment of inorganic and organic tapwater exposures and predicted effects in Puerto Rico, USA

A pilot-scale expanded target assessment of mixtures of inorganic and organic contaminants in point-of-consumption drinking water (tapwater, TW) was conducted in Puerto Rico (PR) to continue to inform TW exposures and corresponding estimations of cumulative human-health risks across the US. In August 2018, a spatial synoptic pilot assessment of than 524 organic, 37 inorganic, and select
Authors
Paul M. Bradley, Ingrid Y. Padilla, Kristin M. Romanok, Kelly Smalling, Michael J. Focazio, Sara E. Breitmeyer, Mary C. Cardon, Justin M. Conley, Nicola Evans, Carrie E. Givens, James L. Gray, L. Earl Gray, Phillip C. Hartig, Michelle L. Hladik, Christopher P. Higgins, Luke R. Iwanowicz, Rachael F. Lane, Keith A. Loftin, R. Blaine McCleskey, Carrie A. McDonough, Elizabeth Medlock-Kakaley, Shannon M. Meppelink, Christopher P. Weis, Vickie S. Wilson
By
Ecosystems Mission Area, Water Resources Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, South Atlantic Water Science Center (SAWSC), National Water Quality Laboratory
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