Tonie Rocke
Tonie Rocke is a Research Epidemiologist at the National Wildlife Health Center.
Science and Products
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Attempts to identify Clostridium botulinum toxin in milk from three experimentally intoxicated Holstein cows
Three adult lactating Holstein cows were injected in the subcutaneous abdominal vein with 175 ng/kg of body weight of Clostridium botulinum type C toxin (451 cow median toxic doses) to determine if this botulinum toxin crosses the blood–milk barrier. Whole blood (in sodium heparin) and clotted blood serum samples were taken at 0 min, 10 min, and 3, 6, 9, and 12 h postinoculation. Milk samples were
Authors
R.B. Moeller, B. Puschner, R.L. Walker, T.E. Rocke, S.R. Smith, J.S. Cullor, A.A. Ardans
Protecting Black-Footed Ferrets and Prairie Dogs against sylvatic plague
Scientists at the USGS National Wildlife Health Center (NWHC), in collaboration with colleagues at other federal agencies and the University of Wisconsin, are developing and testing vaccines that can be used to protect black-footed ferrets and prairie dogs against plague. The black-footed ferret is commonly regarded as the most endangered mammal in North America, and sylvatic plague is a major imp
Authors
Tonie E. Rocke
Exposure of mallards (Anas platyrhynchos) to the hepatotoxic cyanobacterium Nodularia spumigena
Nodularin (NODLN) is a cyclic pentapeptide hepatotoxin produced by the cyanobacterium Nodularia spumigena, which forms extensive blooms during the summer in the Baltic Sea. Nodularin was detected in liver, muscle and/or feather samples of several common eiders (Somateria mollissima) from the Gulf of Finland (northern Baltic Sea) in 2002-2005. Published information on the adverse effects of NODLN i
Authors
V.O. Sipia, J. Christian Franson, O. Sjovall, S. Pflugmacher, Valerie I. Shearn-Bochsler, Tonie E. Rocke, J.A.O. Meriluoto
Immunization of black-tailed prairie dog against plague through consumption of vaccine-laden baits
Prairie dogs (Cynomys spp.) are highly susceptible to Yersinia pestis and, along with other wild rodents, are significant reservoirs of plague for other wildlife and humans in the western United States. A recombinant raccoon poxvirus, expressing the F1 antigen of Y. pestis, was incorporated into a palatable bait and offered to three groups (n=18, 19, and 20) of black-tailed prairie dogs (Cynomys l
Authors
Tonie E. Rocke, Susan Smith, D.T. Stinchcomb, Jorge E. Osorio
Vaccination with F1-V fusion protein protects black-footed ferrets (Mustela nigripes) against plague upon oral challenge with Yersinia pestis
Previous studies have established that vaccination of black-footed ferrets (Mustela nigripes) with F1-V fusion protein by subcutaneous (SC) injection protects the animals against plague upon injection of the bacterium Yersinia pestis. This study demonstrates that the F1-V antigen can also protect ferrets against plague contracted via ingestion of a Y. pestis-infected mouse, a probable route for na
Authors
Tonie E. Rocke, Susan Smith, Paul E. Marinari, J. Kreeger, J.T. Enama, B.S. Powell
Prominent pancreatic endocrinopathy and altered control of food intake disrupt energy homeostasis in prion diseases
Prion diseases are fatal neurodegenerative diseases that can induce endocrinopathies. The basis of altered endocrine function in prion diseases is not well understood, and the purpose of this study was to investigate the spatiotemporal relationship between energy homeostasis and prion infection in hamsters inoculated with either the 139H strain of scrapie agent, which induces preclinical weight ga
Authors
J. D. Bailey, J.G. Berardinelli, T.E. Rocke, R. A. Bessen
Avian botulism
This chapter contains section titled:IntroductionSynonymsHistoryDistributionHost RangeEtiologyEpizootiologyClinical SignsPathogenesisPathologyDiagnosisImmunityPublic Health ConcernsDomestic Animal Health ConcernsWildlife Population ImpactsTreatment and ControlLiterature Cited
Authors
Tonie E. Rocke, Trent K. Bollinger
An outbreak of type C botulism in Herring Gulls (Larus argentatus) in Southeastern Sweden
From 2000 to 2004, over 10,000 seabirds, primarily Herring Gulls (Larus argentatus), died from an undetermined cause in the Blekinge archipelago in southeastern Sweden. In June 2004, 24 affected Herring Gulls were examined clinically, killed humanely, and 23 were examined by necropsy. Seven and 10 unaffected Herring Gulls collected from a local landfill site and from Iceland, respectively, served
Authors
A. Neimanis, D. Gavier-Widen, F. Leighton, T. Bollinger, Tonie E. Rocke, T. Morner
Vaccination as a potential means to prevent plague in black-footed ferrets: Progress and continuing challenges
This study was conducted to further assess the feasibility of vaccinating black-footed ferrets (Mustela nigripes) against plague (caused by the bacterium Yersinia pestis). On days 0 and 28, 17 postreproductive ferrets were immunized by subcutaneous injection with a recombinant fusion protein containing F1 and V antigens from Y. pestis. Another 17 animals received a placebo by the same route. Two w
Authors
Tonie E. Rocke, Pauline Nol, Paul E. Marinari, J.S. Kreeger, Susan R. Smith, G.P. Andrews, A.W. Friedlander
Toxicoinfectious botulism in commercial caponized chickens
During the summer of 2003, two flocks of commercial broiler chickens experienced unusually high death losses following caponizing at 3 wk of age and again between 8 and 14 wk of age. In September, fifteen 11-wk-old live capons were submitted to the Iowa State University Veterinary Diagnostic Laboratory for assistance. In both flocks, the second episode of elevated mortality was associated with inc
Authors
D.W. Trampel, Susan Smith, Tonie E. Rocke
Attempts to identify the source of avian vacuolar myelinopathy for waterbirds
Attempts were made to reproduce avian vacuolar myelinopathy (AVM) in a number of test animals in order to determine the source of the causative agent for birds and to find a suitable animal model for future studies. Submerged vegetation, plankton, invertebrates, forage fish, and sediments were collected from three lakes with ongoing outbreaks of AVM and fed to American coots (Fulica americana), ma
Authors
Tonie E. Rocke, Nancy J. Thomas, Carol U. Meteyer, Charlotte Quist, John R. Fischer, Tom Augspurger, S. E. Ward
The impact of disease in the American white pelican in North America
Records of reported die-offs of the American White Pelican (Pelicanus erythrorhynchos) held by the U.S. Geological Survey National Wildlife Health Center from 1978 through 2003 indicate that type C botulism (caused by Clostridium botulinum) was the major cause of mortality. In 1996, over 15,000 birds, including 8,500 American White Pelicans, were estimated to have died from type C botulism at the
Authors
Tonie E. Rocke, Kathryn A. Converse, Carol U. Meteyer, R. McLean
Science and Products
Filter Total Items: 14
No Result Found
Filter Total Items: 130
Attempts to identify Clostridium botulinum toxin in milk from three experimentally intoxicated Holstein cows
Three adult lactating Holstein cows were injected in the subcutaneous abdominal vein with 175 ng/kg of body weight of Clostridium botulinum type C toxin (451 cow median toxic doses) to determine if this botulinum toxin crosses the blood–milk barrier. Whole blood (in sodium heparin) and clotted blood serum samples were taken at 0 min, 10 min, and 3, 6, 9, and 12 h postinoculation. Milk samples were
Authors
R.B. Moeller, B. Puschner, R.L. Walker, T.E. Rocke, S.R. Smith, J.S. Cullor, A.A. Ardans
Protecting Black-Footed Ferrets and Prairie Dogs against sylvatic plague
Scientists at the USGS National Wildlife Health Center (NWHC), in collaboration with colleagues at other federal agencies and the University of Wisconsin, are developing and testing vaccines that can be used to protect black-footed ferrets and prairie dogs against plague. The black-footed ferret is commonly regarded as the most endangered mammal in North America, and sylvatic plague is a major imp
Authors
Tonie E. Rocke
Exposure of mallards (Anas platyrhynchos) to the hepatotoxic cyanobacterium Nodularia spumigena
Nodularin (NODLN) is a cyclic pentapeptide hepatotoxin produced by the cyanobacterium Nodularia spumigena, which forms extensive blooms during the summer in the Baltic Sea. Nodularin was detected in liver, muscle and/or feather samples of several common eiders (Somateria mollissima) from the Gulf of Finland (northern Baltic Sea) in 2002-2005. Published information on the adverse effects of NODLN i
Authors
V.O. Sipia, J. Christian Franson, O. Sjovall, S. Pflugmacher, Valerie I. Shearn-Bochsler, Tonie E. Rocke, J.A.O. Meriluoto
Immunization of black-tailed prairie dog against plague through consumption of vaccine-laden baits
Prairie dogs (Cynomys spp.) are highly susceptible to Yersinia pestis and, along with other wild rodents, are significant reservoirs of plague for other wildlife and humans in the western United States. A recombinant raccoon poxvirus, expressing the F1 antigen of Y. pestis, was incorporated into a palatable bait and offered to three groups (n=18, 19, and 20) of black-tailed prairie dogs (Cynomys l
Authors
Tonie E. Rocke, Susan Smith, D.T. Stinchcomb, Jorge E. Osorio
Vaccination with F1-V fusion protein protects black-footed ferrets (Mustela nigripes) against plague upon oral challenge with Yersinia pestis
Previous studies have established that vaccination of black-footed ferrets (Mustela nigripes) with F1-V fusion protein by subcutaneous (SC) injection protects the animals against plague upon injection of the bacterium Yersinia pestis. This study demonstrates that the F1-V antigen can also protect ferrets against plague contracted via ingestion of a Y. pestis-infected mouse, a probable route for na
Authors
Tonie E. Rocke, Susan Smith, Paul E. Marinari, J. Kreeger, J.T. Enama, B.S. Powell
Prominent pancreatic endocrinopathy and altered control of food intake disrupt energy homeostasis in prion diseases
Prion diseases are fatal neurodegenerative diseases that can induce endocrinopathies. The basis of altered endocrine function in prion diseases is not well understood, and the purpose of this study was to investigate the spatiotemporal relationship between energy homeostasis and prion infection in hamsters inoculated with either the 139H strain of scrapie agent, which induces preclinical weight ga
Authors
J. D. Bailey, J.G. Berardinelli, T.E. Rocke, R. A. Bessen
Avian botulism
This chapter contains section titled:IntroductionSynonymsHistoryDistributionHost RangeEtiologyEpizootiologyClinical SignsPathogenesisPathologyDiagnosisImmunityPublic Health ConcernsDomestic Animal Health ConcernsWildlife Population ImpactsTreatment and ControlLiterature Cited
Authors
Tonie E. Rocke, Trent K. Bollinger
An outbreak of type C botulism in Herring Gulls (Larus argentatus) in Southeastern Sweden
From 2000 to 2004, over 10,000 seabirds, primarily Herring Gulls (Larus argentatus), died from an undetermined cause in the Blekinge archipelago in southeastern Sweden. In June 2004, 24 affected Herring Gulls were examined clinically, killed humanely, and 23 were examined by necropsy. Seven and 10 unaffected Herring Gulls collected from a local landfill site and from Iceland, respectively, served
Authors
A. Neimanis, D. Gavier-Widen, F. Leighton, T. Bollinger, Tonie E. Rocke, T. Morner
Vaccination as a potential means to prevent plague in black-footed ferrets: Progress and continuing challenges
This study was conducted to further assess the feasibility of vaccinating black-footed ferrets (Mustela nigripes) against plague (caused by the bacterium Yersinia pestis). On days 0 and 28, 17 postreproductive ferrets were immunized by subcutaneous injection with a recombinant fusion protein containing F1 and V antigens from Y. pestis. Another 17 animals received a placebo by the same route. Two w
Authors
Tonie E. Rocke, Pauline Nol, Paul E. Marinari, J.S. Kreeger, Susan R. Smith, G.P. Andrews, A.W. Friedlander
Toxicoinfectious botulism in commercial caponized chickens
During the summer of 2003, two flocks of commercial broiler chickens experienced unusually high death losses following caponizing at 3 wk of age and again between 8 and 14 wk of age. In September, fifteen 11-wk-old live capons were submitted to the Iowa State University Veterinary Diagnostic Laboratory for assistance. In both flocks, the second episode of elevated mortality was associated with inc
Authors
D.W. Trampel, Susan Smith, Tonie E. Rocke
Attempts to identify the source of avian vacuolar myelinopathy for waterbirds
Attempts were made to reproduce avian vacuolar myelinopathy (AVM) in a number of test animals in order to determine the source of the causative agent for birds and to find a suitable animal model for future studies. Submerged vegetation, plankton, invertebrates, forage fish, and sediments were collected from three lakes with ongoing outbreaks of AVM and fed to American coots (Fulica americana), ma
Authors
Tonie E. Rocke, Nancy J. Thomas, Carol U. Meteyer, Charlotte Quist, John R. Fischer, Tom Augspurger, S. E. Ward
The impact of disease in the American white pelican in North America
Records of reported die-offs of the American White Pelican (Pelicanus erythrorhynchos) held by the U.S. Geological Survey National Wildlife Health Center from 1978 through 2003 indicate that type C botulism (caused by Clostridium botulinum) was the major cause of mortality. In 1996, over 15,000 birds, including 8,500 American White Pelicans, were estimated to have died from type C botulism at the
Authors
Tonie E. Rocke, Kathryn A. Converse, Carol U. Meteyer, R. McLean