Fish and Wildlife Disease Investigation and Surveillance

The Challenge: The health of the abundant waterfowl species of Chesapeake Bay has become a major concern due to the spread of Avian Influenza (AI) across North America and the role of waterfowl as a vector of AI. For decades, the health of the Bay’s waterfowl has been affected by the degradation of water quality and food supply due to industrial contaminants,agricultural run-off, pollution from...

Bioinformatics is a relatively new field of science that incorporates elements of biology and computer science together for the purpose of developing efficient and robust methods for the analyses and interpretation of large amounts of biological data, typically DNA or RNA sequence data.

Disease may be caused by infectious agents, nutritional imbalances, physiological or genetically-based abnormalities, and suboptimal environmental conditions, acting either alone or in combination with other factors. In many instances, environmental stressors may merge forces with an infectious agent or some other non-infectious factor to produce or exacerbate a state of disease. By studying...

The Challenge: Neonicotinoid pesticides act as agonists of nicotinic acetylcholine receptors (nAChRs) and are designed to be lethal to insects while theoretically posing little to no threat to vertebrates. The perceived safety of neonicotinoids has led to a sharp increase in their use in the United States and globally, since they were first introduced in 1994. The use of the neonicotinoid...

Mallard duck as such as this pair may be reservoirs of Type A influenza viruses, which under some circumstances may potentially become pathogenic to waterfowl, other wildlife and even humans.

Striped bass ( Morone saxatilis) displaying ulcerative skin lesions and chronic wasting, both typical clinical signs of mycobacteriosis, a bacterial disease that is problematic among many types of fishes around the world.

Whirling disease, caused by the myxosporean parasite Myxobolus cerebralis was identified as an emerging pathogen of trout in the intermountain west region of the U.S. in the early 1990’s. Investigators here worked collaboratively with others to further our understanding of this disease and its impacts on trout and other salmonid fishes.

The image is an investigator performing venipuncture for blood collection for health analysis of a northern snakehead fish collected from a Potomac River tributary in northern Virginia.

Streamside salamanders such as this one are susceptible to invasive fungal pathogens of the genus Batrachochytrium. Two types of emerging fungal agents, B. dendrobatidis and B. salamandrivorans have been identified as serious risks to our amphibian populations.

This rainbow trout is displaying clinical signs of enteric redmouth disease caused by a systemic bacterial infection.

The Challenge: Endocrine active chemicals (EAC) are known to interfere with hormonally regulated physiological processes, thereby affecting signaling in the hypothalamic-pituitary-gonadal-liver (HPGL) axis and commonly resulting in reproductive dysfunction. Computational models that relate hormonal and genomic biomarkers within the HPGL axis to the reproductive cycle and ecologically relevant...

The Challenge: Wild birds are exposed throughout their lives to natural and synthetic chemicals that are present in the environment, many of which interfere with the animal’s physiological and developmental systems. Relative concentrations, routes, frequency, and the environment in which chemical exposure occurs will determine to a large extent the bird’s response. Well-designed avian field...