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Publications

View citations of publications by National Wildlife Health Center scientists since our founding in 1975.  Access to full-text is provided where possible.

Filter Total Items: 1651

Managing prairie dogs by managing plague: a vaccine for the future? Managing prairie dogs by managing plague: a vaccine for the future?

The Black-footed Ferret Recovery Implementation Team Executive Committee is conducting a project to develop, and (hopefully) eventually implement, a plague vaccination program for prairie dogs. The project is a component of the Western Association of Fish and Wildlife Agencies Grasslands Conservation Initiative. An effective, field-worthy vaccine against plague could be the biggest...
Authors
Terry B. Johnson, Tonie E. Rocke, Pete Gober, Bill E. Van Pelt, Michael W. Miller, Daniel W. Tripp, Rachel C. Abbott, David L. Bergman

Season and application rates affect vaccine bait consumption by prairie dogs in Colorado and Utah, USA Season and application rates affect vaccine bait consumption by prairie dogs in Colorado and Utah, USA

Plague, a zoonotic disease caused by the bacterium Yersinia pestis, causes high rates of mortality in prairie dogs (Cynomys spp.). An oral vaccine against plague has been developed for prairie dogs along with a palatable bait to deliver vaccine and a biomarker to track bait consumption. We conducted field trials between September 2009 and September 2012 to develop recommendations for...
Authors
Daniel W. Tripp, Tonie E. Rocke, Sean P. Streich, Nathanael L. Brown, Julia Rodriguez-Ramos Fernandez, Michael W. Miller

A rapid field test for sylvatic plague exposure in wild animals A rapid field test for sylvatic plague exposure in wild animals

Plague surveillance is routinely conducted to predict future epizootics in wildlife and exposure risk for humans. The most common surveillance method for sylvatic plague is detection of antibodies to Yersinia pestis F1 capsular antigen in sentinel animals, such as coyotes (Canis latrans). Current serologic tests for Y. pestis, hemagglutination (HA) test and enzyme-linked immunosorbent...
Authors
Rachel C. Abbott, Robert Hudak, Roy Mondesire, Laurie A. Baeten, Robin E. Russell, Tonie E. Rocke

Lectins stain cells differentially in the coral, Montipora capitata Lectins stain cells differentially in the coral, Montipora capitata

A limitation in our understanding of coral disease pathology and cellular pathogenesis is a lack of reagents to characterize coral cells. We evaluated the utility of plant lectins to stain tissues of a dominant coral, Montipora capitata, from Hawaii. Of 22 lectins evaluated, nine of these stained structures in the upper or basal body wall of corals. Specific structures revealed by...
Authors
Thierry M. Work, Yael Farah

Ocean warming and acidification have complex interactive effects on the dynamics of a marine fungal disease Ocean warming and acidification have complex interactive effects on the dynamics of a marine fungal disease

Diseases threaten the structure and function of marine ecosystems and are contributing to the global decline of coral reefs. We currently lack an understanding of how climate change stressors, such as ocean acidification (OA) and warming, may simultaneously affect coral reef disease dynamics, particularly diseases threatening key reef-building organisms, for example crustose coralline...
Authors
Gareth J. Williams, Nichole N. Price, Blake Ushijima, Greta S. Aeby, Sean M. Callahan, Simon K. Davy, Jamison M. Gove, Maggie D. Johnson, Ingrid S. Knapp, Amanda Shore-Maggio, Jennifer E. Smith, Patrick Videau, Thierry M. Work

A recombinant raccoon poxvirus vaccine expressing both Yersinia pestis F1 and truncated V antigens protects animals against lethal plague. A recombinant raccoon poxvirus vaccine expressing both Yersinia pestis F1 and truncated V antigens protects animals against lethal plague.

In previous studies, we demonstrated in mice and prairie dogs that simultaneous administration of two recombinant raccoon poxviruses (rRCN) expressing Yersinia pestis antigens (F1 and V307-a truncated version of the V protein) provided superior protection against plague challenge compared to individual single antigen constructs. To reduce costs of vaccine production and facilitate...
Authors
Tonie E. Rocke, B Kingstad-Bakke, W Berlier, J.E. Osorio

Book review: Fowler's zoo and wild animal medicine (volume 8) Book review: Fowler's zoo and wild animal medicine (volume 8)

In the eighth volume of Fowler's Zoo and Wild Animal Medicine, the editors have returned to the original, comprehensive, taxa-based format last used in the fifth volume that was released in 2003. The book consists of 82 chapters, divided into taxonomic classes that include amphibians, reptiles, birds, and mammals, and a general topics section. The editors deliberately selected new senior...
Authors
Jonathan M. Sleeman

White-nose syndrome initiates a cascade of physiologic disturbances in the hibernating bat host White-nose syndrome initiates a cascade of physiologic disturbances in the hibernating bat host

Background The physiological effects of white-nose syndrome (WNS) in hibernating bats and ultimate causes of mortality from infection with Pseudogymnoascus (formerly Geomyces) destructans are not fully understood. Increased frequency of arousal from torpor described among hibernating bats with late-stage WNS is thought to accelerate depletion of fat reserves, but the physiological...
Authors
Michelle L. Verant, Carol U. Meteyer, John R. Speakman, Paul M. Cryan, Jeffrey M. Lorch, David S. Blehert

Unique characteristics of the trachea of the juvenile leatherback turtle facilitate feeding, diving and endothermy Unique characteristics of the trachea of the juvenile leatherback turtle facilitate feeding, diving and endothermy

The adult leatherback turtle Dermochelys coriacea overlaps in body size (300–500 kg) with many marine mammals, yet develops from a 50 g hatchling. Adults can dive deeper than 1200 m and have core body temperatures of 25 °C; hatchlings are near-surface dwellers. Juvenile leatherbacks have rarely been studied; here we present anatomical information for the upper respiratory tract of 3...
Authors
John Davenport, T. Todd Jones, Thierry M. Work, George H. Balazs

Trichinosis Trichinosis

Trichinosis, or trichinellosis, is one of the most widespread global parasitic diseases of humans and animals. This ancient disease is caused by the larval stage of parasitic roundworms (nematodes) in the genus Trichinella. Often called the “trichina worm,” this parasite is considered to be the king of the parasite community, because it has adapted to an extremely wide range of hosts...
Authors
William J. Foreyt, Rachel C. Abbott, Charles van Riper

Immunological evaluation of captive green sea turtle (Chelonia mydas) with ulcerative dermatitis Immunological evaluation of captive green sea turtle (Chelonia mydas) with ulcerative dermatitis

Ulcerative dermatitis (UD) is common in captive sea turtles and manifests as skin erosions and ulcers associated with gram-negative bacteria. This study compared clinically healthy and UD-affected captive turtles by evaluating hematology, histopathology, immunoglobulin levels, and delayed-type hypersensitivity assay. Turtles with UD had significantly lower weight, reduced delayed-type
Authors
Fernando Alberto Munoz, Sergio Estrada-Parra, Andres Romero-Rojas, Erik Gonzalez-Ballesteros, Thierry M. Work, Hector Villasenor-Gaona, Iris Estrada-Garcia
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