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Publications

Dive into our publications and explore the science from the Environmental Health Program (Toxic Substances Hydrology and Contaminant Biology).

Filter Total Items: 4097

Tumours in white suckers from Lake Michigan tributaries: Pathology and prevalence Tumours in white suckers from Lake Michigan tributaries: Pathology and prevalence

The prevalence and histopathology of neoplastic lesions were assessed in white suckerCatostomus commersonii captured at two Lake Michigan Areas of Concern (AOCs), the Sheboygan River and Milwaukee Estuary. Findings were compared to those observed at two non-AOC sites, the Root and Kewaunee rivers. At each site, approximately 200 adult suckers were collected during their spawning...
Authors
Vicki S. Blazer, H.L. Walsh, R.P. Braham, C. M. Hahn, P. Mazik, P.B. McIntyre

Chesapeake Bay fish–osprey (Pandion haliaetus) food chain: Evaluation of contaminant exposure and genetic damage Chesapeake Bay fish–osprey (Pandion haliaetus) food chain: Evaluation of contaminant exposure and genetic damage

From 2011 to 2013, a large-scale ecotoxicological study was conducted in several Chesapeake Bay (USA) tributaries (Susquehanna River and flats, the Back, Baltimore Harbor/Patapsco Rivers, Anacostia/ middle Potomac, Elizabeth and James Rivers) and Poplar Island as a mid-Bay reference site. Osprey (Pandion haliaetus) diet and the transfer of contaminants from fish to osprey eggs were...
Authors
Rebecca S. Lazarus, Barnett A. Rattner, Peter C. McGowan, Robert C. Hale, Natalie K. Karouna-Reiner, Richard A. Erickson, Mary Ann Ottinger

Reservoirs and water management influence fish mercury concentrations in the western United States and Canada Reservoirs and water management influence fish mercury concentrations in the western United States and Canada

Anthropogenic manipulation of aquatic habitats can profoundly alter mercury (Hg) cycling and bioaccumulation. The impoundment of fluvial systems is among the most common habitat manipulations and is known to increase fish Hg concentrations immediately following impoundment. However, it is not well understood how Hg concentrations differ between reservoirs and lakes at large spatial and...
Authors
James J. Willacker, Collin A. Eagles-Smith, Michelle A. Lutz, Michael T. Tate, Jesse M. Lepak, Joshua T. Ackerman

Retrospective: Adjusting contaminant concentrations in bird eggs to account for moisture and lipid Loss during their incubation Retrospective: Adjusting contaminant concentrations in bird eggs to account for moisture and lipid Loss during their incubation

By the 1960s, research and monitoring efforts on chlorinated pesticide residues in tissues of wildlife were well underway in North America and Europe. Conservationists and natural resource managers were attempting to resolve whether pesticide exposure and accumulated residues were related to population declines in several species of predatory and scavenging birds (e.g., bald eagle...
Authors
Barnett A. Rattner, Stanley N. Wiemeyer, Lawrence J. Blus

A modeling approach to compare ΣPCB concentrations between congener-specific analyses A modeling approach to compare ΣPCB concentrations between congener-specific analyses

Changes in analytical methods over time pose problems for assessing long-term trends in environmental contamination by polychlorinated biphenyls (PCBs). Congener-specific analyses vary widely in the number and identity of the 209 distinct PCB chemical configurations (congeners) that are quantified, leading to inconsistencies among summed PCB concentrations (ΣPCB) reported by different...
Authors
Polly P. Gibson, Marc A. Mills, Johanna M. Kraus, David M. Walters

Microbial pathogens in source and treated waters from drinking water treatment plants in the United States and implications for human health Microbial pathogens in source and treated waters from drinking water treatment plants in the United States and implications for human health

An occurrence survey was conducted on selected pathogens in source and treated drinking water collected from 25 drinking water treatment plants (DWTPs) in the United States. Water samples were analyzed for the protozoa Giardia and Cryptosporidium (EPA Method 1623); the fungi Aspergillus fumigatus, Aspergillus niger and Aspergillus terreus (quantitative PCR [qPCR]); and the bacteria...
Authors
Dawn N. King, Maura J. Donohue, Stephen J. Vesper, Eric N. Villegas, Michael W. Ware, Megan E. Vogel, Edward Furlong, Dana W. Kolpin, Susan T. Glassmeyer, Stacy Pfaller

Novel cell-based assay for detection of thyroid receptor beta-interacting environmental contaminants Novel cell-based assay for detection of thyroid receptor beta-interacting environmental contaminants

Even though the presence of endocrine disrupting chemicals (EDCs) with thyroid hormone (TH)-like activities in the environment is a major health concern, the methods for their efficient detection and monitoring are still limited. Here we describe a novel cell assay, based on the translocation of a green fluorescent protein (GFP)—tagged chimeric molecule of glucocorticoid receptor (GR)...
Authors
Diana A. Stavreva, Lyuba Varticovski, Ludmila Levkova, Anuja A. George, Luke Davis, Gianluca Pegoraro, Vicki S. Blazer, Luke R. Iwanowicz, Gordon L. Hager

Concentrations and spatial patterns of organic contaminants in tree swallow (Tachycineta bicolor) eggs at United States and binational Great Lakes Areas of Concern, 2010–2015 Concentrations and spatial patterns of organic contaminants in tree swallow (Tachycineta bicolor) eggs at United States and binational Great Lakes Areas of Concern, 2010–2015

Tree swallows, Tachycineta bicolor, were sampled across the Great Lakes basin in 2010 through 2015 to provide a system-wide assessment of current exposure to organic contaminants. The results provide information identified as critical by regulators to assess the “bird or animal deformity or reproductive problems” beneficial use impairment. Eggs were collected from 69 sites across all 5...
Authors
Christine M. Custer, Thomas W. Custer, Paul M. Dummer, Diana R. Goldberg, J. Christian Franson

Investigation of total and hexavalent chromium in filtered and unfiltered groundwater samples at the Tucson International Airport Superfund Site Investigation of total and hexavalent chromium in filtered and unfiltered groundwater samples at the Tucson International Airport Superfund Site

Potential health effects from hexavalent chromium in groundwater have recently become a concern to regulators at the Tucson International Airport Area Superfund site. In 2016, the U.S. Geological Survey sampled 46 wells in the area to characterize the nature and extent of chromium in groundwater, to understand what proportion of total chromium is in the hexavalent state, and to determine...
Authors
Fred D. Tillman, R. Blaine McCleskey, Edyth Hermosillo

Assessing potential health risks to fish and humans using mercury concentrations in inland fish from across western Canada and the United States Assessing potential health risks to fish and humans using mercury concentrations in inland fish from across western Canada and the United States

Fish represent high quality protein and nutrient sources, but Hg contamination is ubiquitous in aquatic ecosystems and can pose health risks to fish and their consumers. Potential health risks posed to fish and humans by Hg contamination in fish were assessed in western Canada and the United States. A large compilation of inland fish Hg concentrations was evaluated in terms of potential...
Authors
Jesse M. Lepak, Mevin Hooten, Collin A. Eagles-Smith, Michael T. Tate, Michelle A. Lutz, Joshua T. Ackerman, James J. Willacker, Allyson K. Jackson, David C. Evers, James G. Wiener, Colleen Flanagan Pritz, Jay Davis

Biogeochemical controls of uranium bioavailability from the dissolved phase in natural freshwaters Biogeochemical controls of uranium bioavailability from the dissolved phase in natural freshwaters

To gain insights into the risks associated with uranium (U) mining and processing, we investigated the biogeochemical controls of U bioavailability in the model freshwater speciesLymnaea stagnalis (Gastropoda). Bioavailability of dissolved U(VI) was characterized in controlled laboratory experiments over a range of water hardness, pH, and in the presence of complexing ligands in the form...
Authors
Marie Noele Croteau, Christopher C. Fuller, Daniel J. Cain, Kate M. Campbell, George R. Aiken

Adverse reproductive and developmental health outcomes following prenatal exposure to a 2 hydraulic fracturing chemical mixture in female C57Bl/6 mice Adverse reproductive and developmental health outcomes following prenatal exposure to a 2 hydraulic fracturing chemical mixture in female C57Bl/6 mice

Unconventional oil and gas operations using hydraulic fracturing can contaminate surface and groundwater with endocrine-disrupting chemicals. We have previously shown that 23 of 24 commonly used hydraulic fracturing chemicals can activate or inhibit the estrogen, androgen, glucocorticoid, progesterone, and/or thyroid receptors in a human endometrial cancer cell reporter gene assay and...
Authors
Christopher D. Kassotis, John J. Bromfield, Kara C. Klemp, Chun-Xia Meng, Andrew R. Wolfe, Thomas Zoeller, Victoria D. Balise, Chiamaka J. Isiguzo, Donald E. Tillitt, Susan C. Nagel
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