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Endocrine Disruption

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Organic Geochemistry Research Core Technology Team

About the Research The Organic Geochemistry Research Laboratory Core Technology Team (CTT) as part of the Environmental Health Program works to develop targeted and non-targeted analytical methods for the identification and quantitation of chemicals that can impact the health of humans and other organisms, and uses bioassays to screen for receptor inhibition.
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Organic Geochemistry Research Core Technology Team

About the Research The Organic Geochemistry Research Laboratory Core Technology Team (CTT) as part of the Environmental Health Program works to develop targeted and non-targeted analytical methods for the identification and quantitation of chemicals that can impact the health of humans and other organisms, and uses bioassays to screen for receptor inhibition.
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Functional and Molecular Bioassay Core Technology Team

About the Research The Functional and Molecular Bioassay Core Technology Team (CTT) as part of the Environmental Health Program utilizes reporter assays, quantitative gene expression analyses, and high-throughput sequencing methods to produce functional endpoints across a broad scope of environmental topics and sample matrices.
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Functional and Molecular Bioassay Core Technology Team

About the Research The Functional and Molecular Bioassay Core Technology Team (CTT) as part of the Environmental Health Program utilizes reporter assays, quantitative gene expression analyses, and high-throughput sequencing methods to produce functional endpoints across a broad scope of environmental topics and sample matrices.
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Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
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Geospatial Analyses and Applications Core Technology Team

About the Research The Geospatial Analyses and Applications Core Technology Team (CTT) as part of the Environmental Health Program collaborates with teams across USGS to develop and apply geospatial analytical methods to answer broad-scale questions about source-sink and cause-effect relationships between contaminants and vulnerable communities.
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Per-and Polyfluoroalkyl Substances (PFAS) Integrated Science Team

Increasing scientific and public awareness of the widespread distribution of per- and poly-fluoroalkyl substances (PFAS) in U.S. drinking-water supplies, aquatic and terrestrial ecosystems, wildlife, and humans has raised many public health and resource management questions that U.S. Geological Survey's (USGS) science can inform. The USGS Environmental Health Program's PFAS Integrated Science Team...
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Per-and Polyfluoroalkyl Substances (PFAS) Integrated Science Team

Increasing scientific and public awareness of the widespread distribution of per- and poly-fluoroalkyl substances (PFAS) in U.S. drinking-water supplies, aquatic and terrestrial ecosystems, wildlife, and humans has raised many public health and resource management questions that U.S. Geological Survey's (USGS) science can inform. The USGS Environmental Health Program's PFAS Integrated Science Team...
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Drinking Water and Wastewater Infrastructure Science Team

The team studies toxicants and pathogens in water resources from their sources, through watersheds, aquifers, and infrastructure to human and wildlife exposures. That information is used to develop decision tools that protect human and wildlife health.
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Drinking Water and Wastewater Infrastructure Science Team

The team studies toxicants and pathogens in water resources from their sources, through watersheds, aquifers, and infrastructure to human and wildlife exposures. That information is used to develop decision tools that protect human and wildlife health.
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Immunomodulation Science Team

The Immunomodulation Integrated Science Team focuses on contaminant and pathogen exposures in the environment that might influence the immune systems of wildlife and the connection to their shared environment with humans. In collaboration with public-health officials, the Team also addresses potential human-health risks stemming from similar exposures. If actual risks are identified, this Team...
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Immunomodulation Science Team

The Immunomodulation Integrated Science Team focuses on contaminant and pathogen exposures in the environment that might influence the immune systems of wildlife and the connection to their shared environment with humans. In collaboration with public-health officials, the Team also addresses potential human-health risks stemming from similar exposures. If actual risks are identified, this Team...
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Refined Model Provides a Screening Tool to Understand Exposure to Contaminants from Incidental Wastewater Reuse

Refinement of the existing national-scale “de facto reuse incidence in our nation’s consumable supply” (DRINCS) model, complemented by field measurements, provides a screening tool to understand human and wildlife exposure to toxicants and pathogens associated with the incidental reuse of treated wastewater in the Shenandoah River watershed. The model results can be accessed in a companion web...
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Refined Model Provides a Screening Tool to Understand Exposure to Contaminants from Incidental Wastewater Reuse

Refinement of the existing national-scale “de facto reuse incidence in our nation’s consumable supply” (DRINCS) model, complemented by field measurements, provides a screening tool to understand human and wildlife exposure to toxicants and pathogens associated with the incidental reuse of treated wastewater in the Shenandoah River watershed. The model results can be accessed in a companion web...
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Intersex in Male Smallmouth Bass in the Missisquoi River in Vermont: Understanding Factors that Can Lead to Endocrine Disruption in Field Settings

The presence of testicular oocytes (intersex) in male smallmouth bass ( Micropterus dolomieu ) in the Missisquoi River in Vermont varied over the period of the study and was not related to concentrations of known endocrine disrupting chemicals in the River. Although previous studies have shown linkages between endocrine disrupting chemical exposures and intersex in fish, these results indicate...
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Intersex in Male Smallmouth Bass in the Missisquoi River in Vermont: Understanding Factors that Can Lead to Endocrine Disruption in Field Settings

The presence of testicular oocytes (intersex) in male smallmouth bass ( Micropterus dolomieu ) in the Missisquoi River in Vermont varied over the period of the study and was not related to concentrations of known endocrine disrupting chemicals in the River. Although previous studies have shown linkages between endocrine disrupting chemical exposures and intersex in fish, these results indicate...
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Sublethal Effects of Contaminants in Aquatic Food Webs—Research Challenges and Considerations for Future Studies

U.S. Geological Survey (USGS) and academic scientists partnered to identify challenges and provide considerations for future scientific study designs to advance our understanding of the often subtle sublethal effects of contaminants on individuals, populations, communities, and entire aquatic food webs.
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Sublethal Effects of Contaminants in Aquatic Food Webs—Research Challenges and Considerations for Future Studies

U.S. Geological Survey (USGS) and academic scientists partnered to identify challenges and provide considerations for future scientific study designs to advance our understanding of the often subtle sublethal effects of contaminants on individuals, populations, communities, and entire aquatic food webs.
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No Evidence of Toxicity to Birds Ingesting Neonicotinoid-Coated Wheat Seeds During Controlled Laboratory Study

Scientists determined what happens to the neonicotinoid insecticide, imidacloprid, on coated wheat seeds once ingested by Japanese quail (Coturnix japonica)—a model species for free-range, seed-eating, upland game birds. Imidacloprid was found to be rapidly adsorbed, metabolized, and excreted, and resulted in no overt signs of toxicity during a controlled laboratory study.
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No Evidence of Toxicity to Birds Ingesting Neonicotinoid-Coated Wheat Seeds During Controlled Laboratory Study

Scientists determined what happens to the neonicotinoid insecticide, imidacloprid, on coated wheat seeds once ingested by Japanese quail (Coturnix japonica)—a model species for free-range, seed-eating, upland game birds. Imidacloprid was found to be rapidly adsorbed, metabolized, and excreted, and resulted in no overt signs of toxicity during a controlled laboratory study.
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Can There be Unintended Benefits when Wastewater Treatment Infrastructure is Upgraded?

Science from the U.S. Geological Survey (USGS) and other entities has shown that a mixture of natural and synthetic estrogens and other similar chemicals are discharged from wastewater treatment plants (WWTPs) to streams and rivers.
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Can There be Unintended Benefits when Wastewater Treatment Infrastructure is Upgraded?

Science from the U.S. Geological Survey (USGS) and other entities has shown that a mixture of natural and synthetic estrogens and other similar chemicals are discharged from wastewater treatment plants (WWTPs) to streams and rivers.
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Are Tumors in Wild Fish Harvested in the Great Lakes Region Related to Contaminants in Water Resources?

Our specialized teams of scientists are working in our laboratories and at field sites around the Great Lakes in collaboration with other federal and state resource agencies to document the prevalence of skin and liver tumors in fish. Tumor prevalence in white suckers ( Catostomus commersonii ), a fish harvested as a food source by local communities, is related to the degree of urbanization in the...
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Are Tumors in Wild Fish Harvested in the Great Lakes Region Related to Contaminants in Water Resources?

Our specialized teams of scientists are working in our laboratories and at field sites around the Great Lakes in collaboration with other federal and state resource agencies to document the prevalence of skin and liver tumors in fish. Tumor prevalence in white suckers ( Catostomus commersonii ), a fish harvested as a food source by local communities, is related to the degree of urbanization in the...
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