Sara J Oyler-McCance, PhD
Dr. Sara Oyler-McCance is a Supervisory Research Geneticist and Branch Chief for the Ecosystem and Organismal Ecology Branch at the Fort Collins Science Center. She is a conservation geneticist studying a wide variety of taxa.
The Molecular Ecology Lab
The FORT Molecular Ecology Laboratory applies genetic and genomic technologies to address a variety of complex questions and conservation issues facing the management of fish and wildlife resources. Together with partners, they design and implement studies to document genetic diversity and the distribution of genetic variation among individuals, populations, and species.
Highlighted Research
- Genome-wide adaptive divergence and conservation translocation
- Genetic connectivity in the Arizona toad (Anaxyrus microscaphus)
- Using fecal DNA to estimate feral horse population size
- A genetic warning system for a wildlife monitoring framework
- Genetic insights into mating strategies of the American black swift
- The transformative impact of genomics on sage-grouse conservation and management
- Environmental DNA (eDNA) sampling improves estimates of invasive Burmese pythons
As a research geneticist and director of the Fort Collins Science Center’s Molecular Ecology Lab, Dr. Oyler-McCance’s research is dedicated to the application and advancement of genetic theory and techniques to address a variety of complex questions and conservation issues facing the management of the Nation's fish and wildlife resources and their habitats. Some of her research involves questions concerning species of conservation concern, yet some involves detection of invasive species. She uses genetic and genomic methods to investigate connectivity and to identify adaptive genetic diversity, both of which are important for ensuring persistence of species in changing landscapes. She uses state-of-the-art technology (for example, novel environmental DNA applications) to detect important invasive species. Her work also explores how to optimally manage the genetic diversity within a species (for example, through translocations) and how to best inventory what species are present and the state of species well-being, persistence, or risk (that is, population size, levels of genetic diversity).
Professional Experience
March 2023 - Present: Branch Chief, Ecosystem and Organismal Ecology Branch, US Geological Survey, Fort Collins Science Center, Fort Collins, Colorado
February 1999 - Present: Research Geneticist, US Geological Survey, Fort Collins Science Center, Fort Collins, Colorado
Education and Certifications
Ph.D. in Fish, Wildlife, and Conservation Biology, Colorado State University, 1999
M.S. in Wildlife Biology, University of Maine, 1993
B.S. in Biology, University of Michigan, 1991
Affiliations and Memberships*
Affiliate Faculty, Ecosystem Science and Sustainability, Colorado State University
Affiliate Faculty, Fish Wildlife and Conservation Biology, Colorado State University
Affiliate Faculty, Graduate Degree Program in Ecology, Colorado State University
Affiliate Faculty, Department of Integrative Biology, University of Colorado, Denver
Science and Products
Combining Novel Technologies for Fast, Field-Ready eDNA Detection of Brown Treesnakes to Enhance Biosecurity Across International Borders
Synthesis of sage-grouse genetic information to support conservation and land management actions
Science for management of America’s iconic wild horses and burros
Molecular Ecology Lab (MEL)
Ecosystem change science in support of wildfire management, water conservation, public land reclamation, and food security
Research to support conservation of America’s national mammal, the bison
Early detection and rapid response tools for invasive tegu lizards
Fish and wildlife science in support of heritage preservation, efficient decision making, wild ungulate management, and outdoor recreation
Invasive species science in support of public safety, America’s natural resources, and economic growth
Developing and evaluating a point-of-use environmental DNA test for rapid field detection of highly invasive brown treesnakes
Fort Collins Science Center Labs and Facilities
Characterizing greater sage-grouse climate-driven maladaptation
Plains bison genetic data and genetic locus panel selection algorithm for monitoring conservation herds Plains bison genetic data and genetic locus panel selection algorithm for monitoring conservation herds
Greater sage-grouse genetic data and R code for evaluating conservation translocations in the northwestern United States, 1992–2021 (ver. 1.1, December 2024) Greater sage-grouse genetic data and R code for evaluating conservation translocations in the northwestern United States, 1992–2021 (ver. 1.1, December 2024)
Whole genome sequencing of three North American large-bodied birds Whole genome sequencing of three North American large-bodied birds
Reduced representation sequencing and genotyping of Arizona Toads (Anaxyrus microscaphus) from the southwestern United States Reduced representation sequencing and genotyping of Arizona Toads (Anaxyrus microscaphus) from the southwestern United States
Sample collection information and microsatellite data for Northern Black Swifts in 6 colonies across Colorado, New Mexico and Idaho Sample collection information and microsatellite data for Northern Black Swifts in 6 colonies across Colorado, New Mexico and Idaho
Voucher and metagenetic sequencing of DNA barcodes of wild-collected bees (Apoidea) from Iowa, USA Voucher and metagenetic sequencing of DNA barcodes of wild-collected bees (Apoidea) from Iowa, USA
Gunnison sage-grouse predicted gene flow (conductance) surfaces, Colorado, United States Gunnison sage-grouse predicted gene flow (conductance) surfaces, Colorado, United States
Genotypes and cluster definitions for a range-wide greater sage-grouse dataset collected 2005-2017 (ver 1.1, January 2023) Genotypes and cluster definitions for a range-wide greater sage-grouse dataset collected 2005-2017 (ver 1.1, January 2023)
Greater sage-grouse genetic warning system, western United States (ver 1.1, January 2023) Greater sage-grouse genetic warning system, western United States (ver 1.1, January 2023)
Greater sage-grouse network-prioritized functional connectivity cumulative current map (raster) Greater sage-grouse network-prioritized functional connectivity cumulative current map (raster)
Microsatellite data, boundaries of subpopulation centers, and estimated effective migration for greater sage-grouse collected in western North America between 1992 and 2015 (ver. 2.0, December 2022) Microsatellite data, boundaries of subpopulation centers, and estimated effective migration for greater sage-grouse collected in western North America between 1992 and 2015 (ver. 2.0, December 2022)
Genetic variation in hoary bats (Lasiurus cinereus) assessed from archived samples Genetic variation in hoary bats (Lasiurus cinereus) assessed from archived samples
Predicted genetic consequences of alternative population control strategies for North American plains bison in Yellowstone National Park Predicted genetic consequences of alternative population control strategies for North American plains bison in Yellowstone National Park
Designing biosurveillance using target analysis for a cryptic invasive species, the brown treesnake (Boiga irregularis) Designing biosurveillance using target analysis for a cryptic invasive species, the brown treesnake (Boiga irregularis)
Riverscape genetics of nonnative Brook Trout to inform native cutthroat trout conservation Riverscape genetics of nonnative Brook Trout to inform native cutthroat trout conservation
Bovine SNP array-based genetic assessment of American plains bison at American Prairie Bovine SNP array-based genetic assessment of American plains bison at American Prairie
Cgsim: An R package for simulation of population genetics for conservation and management applications Cgsim: An R package for simulation of population genetics for conservation and management applications
Assessing shifting technology in genetic monitoring of the North American plains bison Federal conservation herds Assessing shifting technology in genetic monitoring of the North American plains bison Federal conservation herds
Maintenance of genetic diversity despite population fluctuations in the lesser prairie-chicken (Tympanuchus pallidicinctus) Maintenance of genetic diversity despite population fluctuations in the lesser prairie-chicken (Tympanuchus pallidicinctus)
High genetic diversity, low population genetic structure, strong natal philopatry, and longevity revealed in the Black Swift (Cypseloides niger borealis) High genetic diversity, low population genetic structure, strong natal philopatry, and longevity revealed in the Black Swift (Cypseloides niger borealis)
A metapopulation strategy to support long term conservation of genetic diversity in Department of the Interior bison A metapopulation strategy to support long term conservation of genetic diversity in Department of the Interior bison
A genetic assessment of natural barriers for isolating a habitat network proposed for Greenback Cutthroat Trout reintroduction A genetic assessment of natural barriers for isolating a habitat network proposed for Greenback Cutthroat Trout reintroduction
Best practices for genetic and genomic data archiving Best practices for genetic and genomic data archiving
The potential influence of genome-wide adaptive divergence on conservation translocation outcome in an isolated greater sage-grouse population The potential influence of genome-wide adaptive divergence on conservation translocation outcome in an isolated greater sage-grouse population
Non-USGS Publications**
**Disclaimer: The views expressed in Non-USGS publications are those of the author and do not represent the views of the USGS, Department of the Interior, or the U.S. Government.
Science and Products
Combining Novel Technologies for Fast, Field-Ready eDNA Detection of Brown Treesnakes to Enhance Biosecurity Across International Borders
Synthesis of sage-grouse genetic information to support conservation and land management actions
Science for management of America’s iconic wild horses and burros
Molecular Ecology Lab (MEL)
Ecosystem change science in support of wildfire management, water conservation, public land reclamation, and food security
Research to support conservation of America’s national mammal, the bison
Early detection and rapid response tools for invasive tegu lizards
Fish and wildlife science in support of heritage preservation, efficient decision making, wild ungulate management, and outdoor recreation
Invasive species science in support of public safety, America’s natural resources, and economic growth
Developing and evaluating a point-of-use environmental DNA test for rapid field detection of highly invasive brown treesnakes
Fort Collins Science Center Labs and Facilities
Characterizing greater sage-grouse climate-driven maladaptation
Plains bison genetic data and genetic locus panel selection algorithm for monitoring conservation herds Plains bison genetic data and genetic locus panel selection algorithm for monitoring conservation herds
Greater sage-grouse genetic data and R code for evaluating conservation translocations in the northwestern United States, 1992–2021 (ver. 1.1, December 2024) Greater sage-grouse genetic data and R code for evaluating conservation translocations in the northwestern United States, 1992–2021 (ver. 1.1, December 2024)
Whole genome sequencing of three North American large-bodied birds Whole genome sequencing of three North American large-bodied birds
Reduced representation sequencing and genotyping of Arizona Toads (Anaxyrus microscaphus) from the southwestern United States Reduced representation sequencing and genotyping of Arizona Toads (Anaxyrus microscaphus) from the southwestern United States
Sample collection information and microsatellite data for Northern Black Swifts in 6 colonies across Colorado, New Mexico and Idaho Sample collection information and microsatellite data for Northern Black Swifts in 6 colonies across Colorado, New Mexico and Idaho
Voucher and metagenetic sequencing of DNA barcodes of wild-collected bees (Apoidea) from Iowa, USA Voucher and metagenetic sequencing of DNA barcodes of wild-collected bees (Apoidea) from Iowa, USA
Gunnison sage-grouse predicted gene flow (conductance) surfaces, Colorado, United States Gunnison sage-grouse predicted gene flow (conductance) surfaces, Colorado, United States
Genotypes and cluster definitions for a range-wide greater sage-grouse dataset collected 2005-2017 (ver 1.1, January 2023) Genotypes and cluster definitions for a range-wide greater sage-grouse dataset collected 2005-2017 (ver 1.1, January 2023)
Greater sage-grouse genetic warning system, western United States (ver 1.1, January 2023) Greater sage-grouse genetic warning system, western United States (ver 1.1, January 2023)
Greater sage-grouse network-prioritized functional connectivity cumulative current map (raster) Greater sage-grouse network-prioritized functional connectivity cumulative current map (raster)
Microsatellite data, boundaries of subpopulation centers, and estimated effective migration for greater sage-grouse collected in western North America between 1992 and 2015 (ver. 2.0, December 2022) Microsatellite data, boundaries of subpopulation centers, and estimated effective migration for greater sage-grouse collected in western North America between 1992 and 2015 (ver. 2.0, December 2022)
Genetic variation in hoary bats (Lasiurus cinereus) assessed from archived samples Genetic variation in hoary bats (Lasiurus cinereus) assessed from archived samples
Predicted genetic consequences of alternative population control strategies for North American plains bison in Yellowstone National Park Predicted genetic consequences of alternative population control strategies for North American plains bison in Yellowstone National Park
Designing biosurveillance using target analysis for a cryptic invasive species, the brown treesnake (Boiga irregularis) Designing biosurveillance using target analysis for a cryptic invasive species, the brown treesnake (Boiga irregularis)
Riverscape genetics of nonnative Brook Trout to inform native cutthroat trout conservation Riverscape genetics of nonnative Brook Trout to inform native cutthroat trout conservation
Bovine SNP array-based genetic assessment of American plains bison at American Prairie Bovine SNP array-based genetic assessment of American plains bison at American Prairie
Cgsim: An R package for simulation of population genetics for conservation and management applications Cgsim: An R package for simulation of population genetics for conservation and management applications
Assessing shifting technology in genetic monitoring of the North American plains bison Federal conservation herds Assessing shifting technology in genetic monitoring of the North American plains bison Federal conservation herds
Maintenance of genetic diversity despite population fluctuations in the lesser prairie-chicken (Tympanuchus pallidicinctus) Maintenance of genetic diversity despite population fluctuations in the lesser prairie-chicken (Tympanuchus pallidicinctus)
High genetic diversity, low population genetic structure, strong natal philopatry, and longevity revealed in the Black Swift (Cypseloides niger borealis) High genetic diversity, low population genetic structure, strong natal philopatry, and longevity revealed in the Black Swift (Cypseloides niger borealis)
A metapopulation strategy to support long term conservation of genetic diversity in Department of the Interior bison A metapopulation strategy to support long term conservation of genetic diversity in Department of the Interior bison
A genetic assessment of natural barriers for isolating a habitat network proposed for Greenback Cutthroat Trout reintroduction A genetic assessment of natural barriers for isolating a habitat network proposed for Greenback Cutthroat Trout reintroduction
Best practices for genetic and genomic data archiving Best practices for genetic and genomic data archiving
The potential influence of genome-wide adaptive divergence on conservation translocation outcome in an isolated greater sage-grouse population The potential influence of genome-wide adaptive divergence on conservation translocation outcome in an isolated greater sage-grouse population
Non-USGS Publications**
**Disclaimer: The views expressed in Non-USGS publications are those of the author and do not represent the views of the USGS, Department of the Interior, or the U.S. Government.
*Disclaimer: Listing outside positions with professional scientific organizations on this Staff Profile are for informational purposes only and do not constitute an endorsement of those professional scientific organizations or their activities by the USGS, Department of the Interior, or U.S. Government