Iwanowicz, L., L Brown, B Eltz, F Juanes and J Murt (2004) Book Review. In a Perfect Ocean: The state of fisheries and ecosystems in the North Atlantic Ocean. Reviews in Fish Biology and Fisheries.14: 149-151.
Luke R Iwanowicz, Ph.D.
Biography
Biography
Dr. Iwanowicz is a research biologist at the USGS, Leetown Science Center, National Fish Health Research Laboratory in Leetown, WV. His primary research focuses on the application of resident fishes as sentinels of aquatic ecosystem health, the development of molecular tools for field study, and the identification of emerging diseases of fishes. He also leads a Core Technology Team established to evaluate environmental water samples for biological activity including endocrine disrupting activity and toxicity.
Education
- Ph.D. 2008, University of Massachusetts, Amherst, Department of Natural Resources, Advisor: Stephen D. McCormick
- M.S. 2000, University of Arkansas at Pine Bluff, Department of Aquaculture/Fisheries, Advisor: Andrew E. Goodwin
- B.S. 1997, University of Massachusetts, Amherst, Major: Fish Biology, Minor: Biology
Professional Experience
- Editorial Board, Environmental Toxicology and Chemistry, 2016-present
- Adjunct Graduate Faculty, University of Maryland, College Park, 2015-present
- Associate Editor, Journal of Aquatic Animal Health, 2009-2017
- Research Biologist, US Geological Survey, Leetown Science Center, 2008-present
- Research Fish Biologist, US Geological Survey, Leetown Science Center, 2006-2008
- Biological Laboratory Technician, US Geological Survey, Leetown Science Center, 2002-2006
- Scientist II, Virginia Institute of Marine Science, 2001-2002
Selected Awards & Recognition
- U.S. Environmental Protection Agency; Scientific and Technological Achievement Award (2015)
- Spotlight Feature Article, Journal of Virology (2015)
- American Fisheries Society, Most significant paper in Journal of Aquatic Animal Health (2011)
- AFS-Fish Health Section; Special Achievement Award (2011)
- American Fisheries Society, Most significant paper in Journal of Aquatic Animal Health (2004)
Professional Societies
- American Association for the Advancement of Science
- American Society for Microbiology
- American Fisheries Society
- Microbiology Society
- Society for Environmental Toxicology and Chemistry
Science and Products
Date published: October 3, 2019
Status: Completed Intersex in Male Smallmouth Bass in the Missisquoi River in Vermont: Understanding Factors that Can Lead to Endocrine Disruption in Field Settings
The presence of testicular oocytes (intersex) in male smallmouth bass (Micropterus dolomieu) in the Missisquoi River in Vermont varied over the period of the study and was not related to concentrations of known endocrine disrupting chemicals in the River. Although previous studies have shown linkages between endocrine disrupting chemical exposures and intersex in fish, these results...
Contacts: Luke R Iwanowicz, Ph.D.
Date published: April 3, 2019
Status: Active An ecosystem approach to assessing unconventional oil and gas impacts in aquatic ecosystems
The development of unconventional oil and gas (UOG) technology promises economic, societal and national security benefits. However, technological developments in this field have rapidly outpaced scientific studies on potential environmental effects. The effects of accidental UOG-related spills on environmental health are not adequately characterized, often occur in already ecological...
Date published: November 29, 2018
Status: Active Human and Ecological Health Impacts Associated with Water Reuse and Conservation Practices
Human and Ecological Health Impacts Associated with Water Reuse and Conservation Practices
Contacts: Luke R Iwanowicz, Ph.D.
Date published: November 29, 2018
Status: Completed Molecular characterization of unknown virus isolated from the introduced species, the Northern snake head (Channa argus), present in the Chesapeake Bay Watershed
Molecular characterization of unknown virus isolated from the introduced species, the Northern snake head (Channa argus), present in the Chesapeake Bay Watershed
Contacts: Luke R Iwanowicz, Ph.D.
Date published: November 29, 2018
Status: Active Endocrine Disrupting Chemicals and Prevalence of Intersex in Fish Populations in New Jersey
Endocrine Disrupting Chemicals and Prevalence of Intersex in Fish Populations in New Jersey
Contacts: Luke R Iwanowicz, Ph.D.
Date published: November 13, 2018
Status: Active Evaluating the pathogenicity and replication of a novel aquareovirus that infects the endangered fountain darter, Etheostoma fonticola
Evaluating the pathogenicity and replication of a novel aquareovirus that infects the endangered fountain darter, Etheostoma fonticola
Contacts: Luke R Iwanowicz, Ph.D.
Date published: November 9, 2018
Status: Active Prevalence of novel, emerging hepatitis viruses in wild white suckers and their association with liver tumors in the Great Lakes region
Prevalence of novel, emerging hepatitis viruses in wild white suckers and their association with liver tumors in the Great Lakes region
Contacts: Luke R Iwanowicz, Ph.D.
Date published: August 29, 2018
Status: Active Functional and Molecular Bioassays
About the Research
The Environmental Health Program collaborates with scientists srom the Functional and Molecular Bioassay Laboratory to apply and modify microbial and eukaryotic reporter bioassays to detect the presence of bioactive chemicals in environmental water samples. These analyses compliment analytical chemistry and biological datasets. The laboratory adapts...
Contacts: Luke R Iwanowicz, Ph.D.
Date published: May 4, 2018
Status: Archived Endocrine Disrupting Chemicals and Prevalence of Intersex in Fish Populations in New Jersey
NJ WSC and Leetown Science Center scientists in cooperation with the New Jersey Department of Environmental Protection were tasked with characterizing endocrine disruption in smallmouth bass from New Jersey.
Contacts: Kelly Smalling, Luke R Iwanowicz, Ph.D., Sandra Goodrow
Date published: April 16, 2018
Status: Active Molecular tools and methodologies
Molecular tools and methodologies are used designed and used for diverse applications. These applications can be used to assess questions of threatened and endangered species, population and conservation biology, ecological communities, microbial diversity, molecular epidemiology and genomics of non-model organisms among many others. Successful integration of these tools and...
Date published: June 21, 2016
Status: Completed New Hepatitis B Virus Discovered in White Sucker (Catostomus commersonii)
The first known hepatitis B virus to infect fish (white sucker; Catostomus commersonii) has been discovered by U.S. Geological Survey (USGS) scientists.
Contacts: Luke R Iwanowicz, Ph.D.
Date published: February 2, 2015
Status: Completed Channel Catfish (Ictalurus punctatus) White Blood Cells are Functionally Modulated by Estrogens
Estrogens are recognized as modulators of immune responses in mammals, but how these effects might occur in fish was not understood. U.S. Geological Survey (USGS) scientists published findings that fish white blood cells (leukocytes) have specific estrogen receptors (ERs)—a discovery that moves scientists one step closer to understanding the connection between exposure to estrogenic substances...
Contacts: Luke R Iwanowicz, Ph.D.
Date published: September 23, 2020
Water-quality data for a pharmaceutical study at Muddy Creek in North Liberty and Coralville, Iowa, 2017-2018
Surface-water samples were collected, processed, and analyzed for organics, estrogen equivalents, and fecal indicator bacteria. Filtered organic samples were sent to the National Water Quality Laboratory in Denver, Colorado. Unfiltered estrogen equivalent samples were sent to the Organic Geochemistry Research Lab in Lawrence, Kansas, for extraction, after which they were sent to
Attribution: Central Midwest Water Science Center
Year Published: 2021
Pilot-scale expanded assessment of inorganic and organic tapwater exposures and predicted effects in Puerto Rico, USA
A pilot-scale expanded target assessment of mixtures of inorganic and organic contaminants in point-of-consumption drinking water (tapwater, TW) was conducted in Puerto Rico (PR) to continue to inform TW exposures and corresponding estimations of cumulative human-health risks across the US. In August 2018, a spatial synoptic pilot assessment of...
Bradley, Paul; Padilla, Ingrid Y.; Romanok, Kristin; Smalling, Kelly; Focazio, Michael J.; Breitmeyer, Sara; Cardon, Mary C.; Conley, Justin M.; Evans, Nicola; Givens, Carrie E; Gray, James L.; Gray, L. Earl; Hartig, Phillip C.; Hladik, Michelle; Higgins, Christopher P.; Iwanowicz, Luke R.; Lane, Rachael; Loftin, Keith; McCleskey, R. Blaine; McDonough, Carrie A.; Medlock-Kakaley, Elizabeth; Meppelink, Shannon M.; Weis, Christopher P.; Wilson, Vickie S.
Year Published: 2021
Emerging investigator series: Municipal wastewater as a year-round point source of neonicotinoid insecticides that persist in an effluent-dominated stream
Neonicotinoids in aquatic systems have been predominantly associated with agriculture, but some are increasingly being linked to municipal wastewater. Thus, the aim of this work was to understand the municipal wastewater contribution to neonicotinoids in a representative, characterized effluent-dominated temperate-region stream. Our approach was...
Webb, Danielle T.; Zhi, Hui; Kolpin, Dana W.; Klaper, Rebecca D.; Iwanowicz, Luke R.; LeFevre, Gregory H.
Year Published: 2021
Public and private tapwater: Comparative analysis of contaminant exposure and potential risk, Cape Cod, Massachusetts, USA
BackgroundHumans are primary drivers of environmental contamination worldwide, including in drinking-water resources. In the United States (US), federal and state agencies regulate and monitor public-supply drinking water while private-supply monitoring is rare; the current lack of directly comparable information on contaminant-mixture exposures...
Bradley, Paul; LeBlanc, Denis R.; Romanok, Kristin; Smalling, Kelly; Focazio, Michael J.; Cardon, Mary C.; Clark, Jimmy; Conley, Justin M.; Evans, Nicola; Givens, Carrie E; Gray, James L.; Gray, L. Earl; Hartig, Phillip C.; Higgins, Christopher P.; Hladik, Michelle; Iwanowicz, Luke R.; Loftin, Keith; McCleskey, R. Blaine; McDonough, Carrie A.; Medlock-Kakaley, Elizabeth; Weis, Christopher P.; Wilson, Vickie S.Attribution: California Water Science Center, Eastern Ecological Science Center, Leetown Science Center, New England Water Science Center, New Jersey Water Science Center, South Atlantic Water Science Center (SAWSC), Upper Midwest Water Science Center, Ecosystems, Water Resources, Region 1: North Atlantic-Appalachian, Region 2: South Atlantic-Gulf (Includes Puerto Rico and the U.S. Virgin Islands), National Water Quality Laboratory
View Citation
https://doi.org/10.1016/j.envint.2021.106487
Year Published: 2021
Genome sequences of 26 white sucker hepatitis B virus isolates from white sucker, catostomus commersonii, inhabiting transboundary waters from Alberta, Canada, to the Great Lakes, USA
We report 26 genomes of the white sucker hepatitis B virus (WSHBV) from the white sucker, Catostomus commersonii. Genome length ranged from 3541 to 3543 bp and nucleotide identity was 96.7% or greater across genomes. This work suggests a geographical range of this virus that minimally extends from the Athabasca River, Alberta, Canada to the Great...
Adams, Cynthia R.; Blazer, Vicki S.; Sherry, Jim; Cornman, Robert S.; Iwanowicz, Luke R.
Year Published: 2021
Production and characterization of a mouse monoclonal antibody against smallmouth bass (Micropterus dolomieu) IgM
A murine monoclonal antibody (mAb, IgG2a) was produced for the detection of smallmouth bass (Micropterus dolomieu) immunoglobulin (IgM). The antibody is specific for IgM heavy chain and was shown to also recognize the Ig heavy chain of largemouth bass (Micropterus salmoides) and bluegill (Lepomis...
Ottinger, Christopher A.; Smith, Cheyenne R.; Blazer, Vicki S.; Iwanowicz, Luke R.; Vogelbein, Mary Ann; Kaattari, Stephen
Year Published: 2021
Phylogeographic genetic diversity in the white sucker hepatitis B Virus across the Great Lakes Region and Alberta, Canada
Hepatitis B viruses belong to a family of circular, double-stranded DNA viruses that infect a range of organisms, with host responses that vary from mild infection to chronic infection and cancer. The white sucker hepatitis B virus (WSHBV) was first described in the white sucker (Catostomus commersonii), a freshwater teleost, and belongs to the...
Adams, Cynthia R; Blazer, Vicki S.; Sherry, Jim; Cornman, Robert S.; Iwanowicz, Luke R.
Year Published: 2021
Modeling estrogenic activity in streams throughout the Potomac and Chesapeake Bay watersheds
Endocrine-disrupting compounds (EDCs), specifically estrogenic endocrine-disrupting compounds, vary in concentration and composition in surface waters under the influence of different landscape sources and landcover gradients. Estrogenic activity in surface waters may lead to adverse effects in aquatic species at both individual and population...
Gordon, Stephanie; Jones, Daniel K.; Blazer, Vicki S.; Iwanowicz, Luke R.; Williams, Brianna; Smalling, KellyAttribution: Chesapeake Bay Activities, Eastern Ecological Science Center, Eastern Geographic Science Center, Leetown Science Center, New Jersey Water Science Center, Pennsylvania Water Science Center, Utah Water Science Center, Ecosystems, Water Resources, Region 1: North Atlantic-Appalachian, Region 7: Upper Colorado Basin
Year Published: 2021
In vitro effects-based method and water quality screening model for use in pre- and post-distribution treated waters
Recent urban public water supply contamination events emphasize the importance of screening treated drinking water quality after distribution. In vitro bioassays, when run concurrently with analytical chemistry methods, are effective tools to evaluating the efficacy of water treatment processes and water quality. We tested 49 water...
Medlock-Kakaley, Elizabeth; Cardon, Mary C.; Evans, Nicola; Iwanowicz, Luke R.; Allen, Joshua M.; Wagner, Elizabeth; Bokenkamp, Katherine; Richardson, Susan D; Plewa, Michael J; Bradley, Paul; Romanok, Kristin; Kolpin, Dana W.; Conley, Justin M.; Gray, L. Earl Jr.; Hartig, Phillip C.; Wilson, Vickie S.Attribution: Eastern Ecological Science Center, Leetown Science Center, New Jersey Water Science Center, South Atlantic Water Science Center (SAWSC), Upper Midwest Water Science Center, Ecosystems, Water Resources, Region 5: Missouri Basin, Region 1: North Atlantic-Appalachian, Region 2: South Atlantic-Gulf (Includes Puerto Rico and the U.S. Virgin Islands)
Year Published: 2021
Monitoring wetland water quality related to livestock grazing in amphibian habitats
Land use alteration such as livestock grazing can affect water quality in habitats of at-risk wildlife species. Data from managed wetlands are needed to understand levels of exposure for aquatic life stages and monitor grazing-related changes afield. We quantified spatial and temporal variation in water quality in wetlands occupied by threatened...
Smalling, Kelly; Rowe, Jennifer; Pearl, Christopher; Iwanowicz, Luke R.; Givens, Carrie E.; Anderson, Chauncey W.; McCreary, Brome; Adams, Michael J.Attribution: Eastern Ecological Science Center, Forest and Rangeland Ecosystem Science Center, Leetown Science Center, Michigan Water Science Center, Michigan-Ohio Water Science Center, New Jersey Water Science Center, Oregon Water Science Center, Upper Midwest Environmental Sciences Center, Upper Midwest Water Science Center, Ecosystems, Water Resources, Region 9: Columbia-Pacific Northwest, Region 1: North Atlantic-Appalachian
Year Published: 2021
Evidence that watershed nutrient management practices effectively reduce estrogens in environmental waters
We evaluate the impacts of different nutrient management strategies on the potential for co-managing estrogens and nutrients in environmental waters of the Potomac watershed of the Chesapeake Bay. These potential co-management approaches represent agricultural and urban runoff, wastewater treatment plant effluent, and combined sewer overflow...
Duan, Shuiwang; Iwanowicz, Luke R.; Noguera-Oviedo, Katia; Kaushal, Sujay S.; Rosenfeld, Erik; Aga, Diana; Murthy, Sudhir
Year Published: 2021
Retrospective analysis of estrogenic endocrine disruption and land-use influences in the Chesapeake Bay watershed
The Chesapeake Bay is the largest estuary in the United States and its watershed includes river drainages in six states and the District of Columbia. Sportfishing is of major economic interest, however, the rivers within the watershed provide numerous other ecological, recreational, cultural and economic benefits, as well as serving as a drinking...
Blazer, Vicki S.; Gordon, Stephanie; Jones, Daniel K.; Iwanowicz, Luke R.; Walsh, Heather L.; Sperry, Adam; Smalling, Kelly
Year Published: 2020
Occurrence and spatiotemporal dynamics of pharmaceuticals in a temperate-region wastewater effluent-dominated stream: Variable inputs and differential attenuation yield evolving complex exposure mixtures
Effluent-dominated streams are becoming increasingly common in temperate regions and generate complex pharmaceutical mixture exposure conditions that may impact aquatic organisms via drug–drug interactions. Here, we quantified spatiotemporal pharmaceutical exposure concentrations and composition mixture dynamics during baseflow conditions at four...
Zhi, Hui; Kolpin, Dana W.; Klaper, R.D.; Iwanowicz, Luke R.; Meppelink, Shannon M.; LeFevre, Gregory H.Pre-USGS Publications
McIntire, M., L R Iwanowicz and A E Goodwin (2003) Molecular, physical and clinical evidence that Golden Shiner Virus (GSV) and Grass Carp Reovirus (GCRV) are variants of the same virus. Journal of Aquatic Animal Health. 15: 257-263.
Iwanowicz, L.R. and A E Goodwin (2002) Characterization of a new bacilliform fathead minnow rhabdovirus that produces syncytia in tissue culture. Archives of Virology 147: 889 – 916.
Iwanowicz, L.R. A E Goodwin and J Harshbarger (2001) Embryonal rhabdomyosarcoma of the giant gourami, Colisa fasciata (Bloch & Schneider). Journal of Fish Diseases 24:177-179
Iwanowicz, L.R. A E Goodwin and N Heil (2000) A small RNA virus isolated from apparently healthy wild sandbar shiners, Notropis scepticus. Journal of Fish Diseases 23: 349-352.
Date published: December 17, 2015
Intersex Prevalent in Black Bass Inhabiting National Wildlife Refuges in Northeast
Eighty five percent of male smallmouth bass and 27 percent of male largemouth bass tested in waters in or near 19 National Wildlife Refuges in the Northeast U.S. were intersex, according to a new study by U.S. Geological Survey and U.S. Fish and Wildlife Service researchers.
Attribution: Ecosystems
Date published: September 25, 2015
Hepatitis B-like Virus Found in Great Lakes Fish Species
A hepatitis B-like virus has been found for the first time in fish. A team of USGS researchers found the virus in white sucker from the Great Lakes Region using gene-sequencing technologies.
Attribution: Ecosystems