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Images from the National Wildlife Health Center.

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Gross photographs from a Cooper’s hawk showing Air sac overlying the lung and liver with yellow to green, irregular nodules.
Gross photographs from a Cooper’s hawk (Accipiter cooperii)
Gross photographs from a Cooper’s hawk (Accipiter cooperii)
Gross photographs from a Cooper’s hawk (Accipiter cooperii)

Gross photographs from a Cooper’s hawk (Accipiter cooperii). (A) Air sac overlying the lung and liver have multiple yellow to green, irregular nodules (arrows). (B) Liver (asterisk) has multiple 1 mm, round to irregular, tan nodules in addition to innumerable miliary foci.

Gross photographs from a Cooper’s hawk (Accipiter cooperii). (A) Air sac overlying the lung and liver have multiple yellow to green, irregular nodules (arrows). (B) Liver (asterisk) has multiple 1 mm, round to irregular, tan nodules in addition to innumerable miliary foci.

Healthy elkhorn coral tissue next to elkhorn coral with tissue loss shown by atrophic and thin body wall.
Photomicrograph from a healthy example of elkhorn coral side-by-side with elkhorn coral found with multifocal tissue loss
Photomicrograph from a healthy example of elkhorn coral side-by-side with elkhorn coral found with multifocal tissue loss
Photomicrograph from a healthy example of elkhorn coral side-by-side with elkhorn coral found with multifocal tissue loss

(A) Photomicrograph from a healthy example of elkhorn coral (Acropora palmata). Tall columnar epidermis (E), gastrodermis (g), skeletal space (s), gastrovascular cavity (gvc), and calicodermis (white arrowhead). H&E stain.

Photomicrograph at low magnification from elkhorn coral showing flatworm along body wall.
Photomicrograph at low magnification from elkhorn coral (Acropora palmata) found with multifocal tissue loss in the Dominican Republic
Photomicrograph at low magnification from elkhorn coral (Acropora palmata) found with multifocal tissue loss in the Dominican Republic
Photomicrograph at low magnification from elkhorn coral (Acropora palmata) found with multifocal tissue loss in the Dominican Republic

Photomicrograph at low magnification from elkhorn coral (Acropora palmata) found with multifocal tissue loss in the Dominican Republic. A flatworm (fw) is present along a multifocally ulcerated coral surface body wall (c) along one polyp. A small amount of cellular debris can be seen within the pharynx (p) of the flatworm.

Photomicrographs of from unknown species of flatworm
Photomicrographs of from unknown species of flatworm
Photomicrographs of from unknown species of flatworm
Photomicrographs of from unknown species of flatworm

Photomicrographs of from unknown species of flatworm. (A) Dorsal detail showing epidermis with rhabdites (black arrowheads) and endosymbionts visible within the flatworm parenchyma (fw).

Photomicrographs of from unknown species of flatworm. (A) Dorsal detail showing epidermis with rhabdites (black arrowheads) and endosymbionts visible within the flatworm parenchyma (fw).

Photographs of elkhorn coral show white portions where tissue loss has occurred.
Photographs from an elkhorn coral colony (Acropora palmata) losing tissue on a reef in the Dominican Republic
Photographs from an elkhorn coral colony (Acropora palmata) losing tissue on a reef in the Dominican Republic
Photographs from an elkhorn coral colony (Acropora palmata) losing tissue on a reef in the Dominican Republic

Photographs from an elkhorn coral colony (Acropora palmata) losing tissue on a reef in the Dominican Republic. (A) Colony in situ with bright white skeleton exposed by multifocal tissue loss (arrowheads) and areas of older tissue loss with algae overgrowth (*).  (B) Submitted samples. Gross lesions are obscured by with loss of pigment with fixation.

Photographs from an elkhorn coral colony (Acropora palmata) losing tissue on a reef in the Dominican Republic. (A) Colony in situ with bright white skeleton exposed by multifocal tissue loss (arrowheads) and areas of older tissue loss with algae overgrowth (*).  (B) Submitted samples. Gross lesions are obscured by with loss of pigment with fixation.

Photographs of Mexican wolf brain showing lesions.
Photographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York
Photographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York
Photographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York

Photographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York, USA. (A) An area of light gray discoloration is present on the surface of the left cranio-dorsal cerebrum (arrow).

Photomicrographs from a Mexican Wolf euthanized due to neurologic illness.
Photomicrographs from a Mexican Wolf euthanized due to neurologic illness.
Photomicrographs from a Mexican Wolf euthanized due to neurologic illness.
Photomicrographs from a Mexican Wolf euthanized due to neurologic illness.

Photomicrographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York, USA. (A) Most of the neoplasm consists of loosely arranged, highly vacuolated stellate cells within a variably fine fibrovascular stroma. (B) An area of necrosis (asterisk) surrounded by pseudopalisading neoplastic cells (arrows).

Photomicrographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York, USA. (A) Most of the neoplasm consists of loosely arranged, highly vacuolated stellate cells within a variably fine fibrovascular stroma. (B) An area of necrosis (asterisk) surrounded by pseudopalisading neoplastic cells (arrows).

Photomicrographs from a Mallard Duck with amyloidosis
Photomicrographs of Amyloidosis in a Mallard Duck
Photomicrographs of Amyloidosis in a Mallard Duck
Photomicrographs of Amyloidosis in a Mallard Duck

Photomicrographs from a Mallard Duck (Anas platyrhynchos) found dead in Missouri, U.S.A. (A) The glomerular mesangium (asterisk) is expanded by amorphous, eosinophilic, acellular material. H&E stain. (B) Tubules in medullary cones are often surrounded by amorphous, eosinophilic, acellular material. H&E stain.

Photomicrographs from a Mallard Duck (Anas platyrhynchos) found dead in Missouri, U.S.A. (A) The glomerular mesangium (asterisk) is expanded by amorphous, eosinophilic, acellular material. H&E stain. (B) Tubules in medullary cones are often surrounded by amorphous, eosinophilic, acellular material. H&E stain.

Photomicrographs from an eastern massasauga rattlesnake showing necrosis and fungal hyphae.
Photomicrographs from an eastern massasauga rattlesnake (Sistrurus catenatus) from Wisconsin
Photomicrographs from an eastern massasauga rattlesnake (Sistrurus catenatus) from Wisconsin
Photomicrographs from an eastern massasauga rattlesnake (Sistrurus catenatus) from Wisconsin

Photomicrographs from an eastern massasauga rattlesnake (Sistrurus catenatus) from Wisconsin, U.S.A. Periodic acid-Shiff. (A) On the ventral neck are multifocal areas of superficial to mid-epidermal necrosis (arrows). (B) Areas of necrosis often contain ~5-µm diameter branching, septate, PAS-positive fungal hyphae (arrowheads).

Photomicrographs from an eastern massasauga rattlesnake (Sistrurus catenatus) from Wisconsin, U.S.A. Periodic acid-Shiff. (A) On the ventral neck are multifocal areas of superficial to mid-epidermal necrosis (arrows). (B) Areas of necrosis often contain ~5-µm diameter branching, septate, PAS-positive fungal hyphae (arrowheads).

Photos of eastern massasauga rattlesnake showing discolored scales and nodule on lung.
Photographs from an eastern massasauga rattlesnake with snake fungal disease
Photographs from an eastern massasauga rattlesnake with snake fungal disease
Photographs from an eastern massasauga rattlesnake with snake fungal disease

Photographs from an eastern massasauga rattlesnake (Sistrurus catenatus) found lethargic in Wisconsin, U.S.A. (A) There is a 15 x 12 mm area with firm, misshapen, and discolored scales (arrows) on the ventral neck. (B) There is a 10 x 6 focal area of depression with tan to dark red scale discoloration (arrow) on the ventral body.

Photographs from an eastern massasauga rattlesnake (Sistrurus catenatus) found lethargic in Wisconsin, U.S.A. (A) There is a 15 x 12 mm area with firm, misshapen, and discolored scales (arrows) on the ventral neck. (B) There is a 10 x 6 focal area of depression with tan to dark red scale discoloration (arrow) on the ventral body.

Photomicrograph from a boulder brain coral found diseased in Biscayne Bay showing lesions in body wall.
Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida
Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida
Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida

Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, FL, US. There is lytic necrosis of the gastrodermis extending through the surface body wall (asterisk), and mucocyte hyperplasia with loss of gastrodermis from surface and basal body walls (black arrowheads.

Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, FL, US. There is lytic necrosis of the gastrodermis extending through the surface body wall (asterisk), and mucocyte hyperplasia with loss of gastrodermis from surface and basal body walls (black arrowheads.

Photomicrograph from a boulder brain coral found diseased in Biscayne Bay showing lesions in body wall.
Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida
Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida
Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida

Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, FL, US. There is multifocal lytic necrosis of the gastrodermis extending through the surface and basal body walls (asterisks), and mucocyte hyperplasia with loss of gastrodermis from surface and basal body walls (black arrowheads).

Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, FL, US. There is multifocal lytic necrosis of the gastrodermis extending through the surface and basal body walls (asterisks), and mucocyte hyperplasia with loss of gastrodermis from surface and basal body walls (black arrowheads).

Colony of boulder brain coral with white new tissue loss areas and greenish-brown healthy tissue.
Photographs from a colony of boulder brain coral (Colpophyllia natans) found losing tissue in Biscayne Bay, Miami, Florida
Photographs from a colony of boulder brain coral (Colpophyllia natans) found losing tissue in Biscayne Bay, Miami, Florida
Photographs from a colony of boulder brain coral (Colpophyllia natans) found losing tissue in Biscayne Bay, Miami, Florida

Photographs from a colony of boulder brain coral (Colpophyllia natans) found losing tissue in Biscayne Bay, Miami, FL, US. (A). In situ photograph. An area of prior tissue loss is covered in algal overgrowth (O), new loss is evidenced by white, bare skeleton not yet overgrown by algae (S), and intact healthy-appearing tissue is greenish brown (H).

Photomicrograph from a boulder brain coral found diseased in Biscayne Bay showing lesions in basal body wall.
Photomicrograph of basal body wall from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida - cloned
Photomicrograph of basal body wall from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida - cloned
Photomicrograph of basal body wall from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida - cloned

Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, FL, US. Within the basal body wall are necrotic “ghost” dinoflagellate endosymbionts with pale eosinophilic cytoplasm, lysis of nucleus, and loss of spherical shape (arrowheads). Normal endosymbionts are circled.

An arrow points to a focus of bony proliferation is seen on a radiograph of the left proximal radius.
Image from a Timber Wolf (Canis lupus) found dead in Northern Wisconsin, USA
Image from a Timber Wolf (Canis lupus) found dead in Northern Wisconsin, USA
Image from a Timber Wolf (Canis lupus) found dead in Northern Wisconsin, USA

Image from a Timber Wolf (Canis lupus) found dead in Northern Wisconsin, USA. A focus of bony proliferation is seen on a radiograph of the left proximal radius (arrow).

Image shows a plastic bag lodged in the cardia of the stomach of a timber wolf. Carcass has a tag with specimen info.
Image from a Timber Wolf showing plastic bag lodged in the cardia of the stomach
Image from a Timber Wolf showing plastic bag lodged in the cardia of the stomach
Image from a Timber Wolf showing plastic bag lodged in the cardia of the stomach

Image from a Timber Wolf (Canis lupus) found dead in Northern Wisconsin, USA. Ulceration of the mucosa of the distal esophagus (arrows). A plastic bag was extracted from where it was tightly lodged in the cardia of the stomach.

Round yeasts present in necrotic debris within an area of osteomyelitis in the atlas of timber wolf.
Image from a Timber Wolf found dead in Northern Wisconsin, USA showing round yeasts in necrotic debris within an area of osteomyelitis in the atlas
Image from a Timber Wolf found dead in Northern Wisconsin, USA showing round yeasts in necrotic debris within an area of osteomyelitis in the atlas
Image from a Timber Wolf found dead in Northern Wisconsin, USA showing round yeasts in necrotic debris within an area of osteomyelitis in the atlas

Image from a Timber Wolf (Canis lupus) found dead in Northern Wisconsin, USA. Multiple 8-20 micron, extracellular, round yeasts, some exhibiting broad-based budding, are present in necrotic debris within an area of osteomyelitis in the atlas (arrow) (markedly autolyzed tissue). Grocott’s Methenamine Silver (GMS) stain.

Photomicrographs from a Common Grackle showing lesions in pulmonary blood vessel and nematodes in brain and pulmonary artery.
Photomicrographs from a Common Grackle (Quiscalus quiscula) found dead in Ohio
Photomicrographs from a Common Grackle (Quiscalus quiscula) found dead in Ohio
Photomicrographs from a Common Grackle (Quiscalus quiscula) found dead in Ohio

Photomicrographs from a Common Grackle (Quiscalus quiscula) found dead in Ohio, U.S.A. H&E stains. (A) Longitudinal (arrow) and cross sections (arrowheads) of microfilariae in a pulmonary blood vessel. (B) Microfilariae (arrows) within a parabronchus. (C) Microfilaria (arrow) within the cerebellar parenchyma with no associated inflammation.

Photomicrographs from a Common Grackle (Quiscalus quiscula) found dead in Ohio, U.S.A. H&E stains. (A) Longitudinal (arrow) and cross sections (arrowheads) of microfilariae in a pulmonary blood vessel. (B) Microfilariae (arrows) within a parabronchus. (C) Microfilaria (arrow) within the cerebellar parenchyma with no associated inflammation.

Photomicrographs from a Fisher showing lesions in brain blood vessel, pancreas, and liver.
Photomicrographs from a Fisher (Pekania pennanti) found dead in Wisconsin, USA
Photomicrographs from a Fisher (Pekania pennanti) found dead in Wisconsin, USA
Photomicrographs from a Fisher (Pekania pennanti) found dead in Wisconsin, USA

Photomicrographs from a Fisher (Pekania pennanti) found dead in Wisconsin, USA. (A) Blood vessels in the brain are surrounded by low numbers of lymphocytes and plasma cells (arrows). H&E stain. (B) A blood vessel in the brain is surrounded by low numbers of lymphocytes and plasma cells (black arrow).

Photomicrographs from a Fisher (Pekania pennanti) found dead in Wisconsin, USA. (A) Blood vessels in the brain are surrounded by low numbers of lymphocytes and plasma cells (arrows). H&E stain. (B) A blood vessel in the brain is surrounded by low numbers of lymphocytes and plasma cells (black arrow).

Photos from a bald eagle. Left: Reddened pancreas with tan foci of necrosis. Right: Spleen with tan foci.
Photographs from a Bald Eagle (Haliaeetus leucocephalus) with highly pathogenic avian influenza found dead in Wisconsin
Photographs from a Bald Eagle (Haliaeetus leucocephalus) with highly pathogenic avian influenza found dead in Wisconsin
Photographs from a Bald Eagle (Haliaeetus leucocephalus) with highly pathogenic avian influenza found dead in Wisconsin

Photographs from a Bald Eagle (Haliaeetus leucocephalus) with highly pathogenic avian influenza found dead in Wisconsin, USA.  (A) The pancreas is reddened and has pinpoint to coalescing tan foci of necrosis (arrows). (B) The spleen contains pinpoint tan foci (arrows). 

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