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Images from the National Wildlife Health Center.

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Map of North America showing locations where chronic wasting disease has been detected.
Distribution of Chronic Wasting Disease in North America
Distribution of Chronic Wasting Disease in North America
Distribution of Chronic Wasting Disease in North America

Distribution of Chronic Wasting Disease in North America, updated April 19, 2024.

Photos showing discard on raccoon eye, crusty nasal planum, and lesions in airway.
Photographs and photomicrographs from a Common Raccoon (Procyon lotor) found dead in Wisconsin
Photographs and photomicrographs from a Common Raccoon (Procyon lotor) found dead in Wisconsin
Photographs and photomicrographs from a Common Raccoon (Procyon lotor) found dead in Wisconsin

Photographs and photomicrographs from a Common Raccoon (Procyon lotor) found dead in Wisconsin, USA. (A) There is green-gray mucoid discharge around the eyes and the nasal planum is crusty (arrows).

Photographs and photomicrographs from a Common Raccoon (Procyon lotor) found dead in Wisconsin, USA. (A) There is green-gray mucoid discharge around the eyes and the nasal planum is crusty (arrows).

GIF with maps showing chronic wasting disease distribution in North America prior to 2000 and yearly from 2004-2023.
Chronic wasting disease: change in documented distribution in North America 2000-2023
Chronic wasting disease: change in documented distribution in North America 2000-2023
Chronic wasting disease: change in documented distribution in North America 2000-2023

Animated GIF showing changes in distribution of chronic wasting disease in North America from 2000-2023 as documented at the end of each year. Individual files of yearly maps are available at https://doi.org/10.5066/P9HQKKFO.

Animated GIF showing changes in distribution of chronic wasting disease in North America from 2000-2023 as documented at the end of each year. Individual files of yearly maps are available at https://doi.org/10.5066/P9HQKKFO.

Images of tissues from a gull showing lesions and bacteria.
Tissue from a gull (Larus sp) from Wisconsin
Tissue from a gull (Larus sp) from Wisconsin
Tissue from a gull (Larus sp) from Wisconsin

Tissue from a gull (Larus sp) from Wisconsin. (A) Diffusely the pericardium (star) is greatly expanded by fibrin, edema and necrotic debris (H&E). (B) Lymphoplasmacytic myositis (arrows) creating linear lesions along fascial planes of the pectoral skeletal muscle (H&E).

Tissue from a gull (Larus sp) from Wisconsin. (A) Diffusely the pericardium (star) is greatly expanded by fibrin, edema and necrotic debris (H&E). (B) Lymphoplasmacytic myositis (arrows) creating linear lesions along fascial planes of the pectoral skeletal muscle (H&E).

Map of North America showing locations of chronic wasting disease in red and tribal lands in grey.
Distribution of CWD in Relation to Tribal Lands in the U.S.
Distribution of CWD in Relation to Tribal Lands in the U.S.
Distribution of CWD in Relation to Tribal Lands in the U.S.

Distribution of Chronic Wasting Disease in North America, in Relation to Tribal Lands in the Conterminous United States. Updated on February 27, 2024.

Distribution of Chronic Wasting Disease in North America, in Relation to Tribal Lands in the Conterminous United States. Updated on February 27, 2024.

Photomicrographs of the plagiopatagium from a Little Brown Bat showing nematodes.
Photomicrographs of the plagiopatagium from a Little Brown Bat
Photomicrographs of the plagiopatagium from a Little Brown Bat
Photomicrographs of the plagiopatagium from a Little Brown Bat

Photomicrographs of the plagiopatagium from a Little Brown Bat (Myotis lucifugus) captured live in Wyoming, U.S.A. (A) Adult nematodes (asterisks) are present in the dermis. They are filled with larval nematodes (arrowhead). The overlying epidermis is hyperplastic (arrow). H&E stain.

Photomicrographs of the plagiopatagium from a Little Brown Bat (Myotis lucifugus) captured live in Wyoming, U.S.A. (A) Adult nematodes (asterisks) are present in the dermis. They are filled with larval nematodes (arrowhead). The overlying epidermis is hyperplastic (arrow). H&E stain.

Gross photographs from a Cooper’s hawk showing Air sac overlying the lung and liver with yellow to green, irregular nodules.
Gross photographs from a Cooper’s hawk (Accipiter cooperii)
Gross photographs from a Cooper’s hawk (Accipiter cooperii)
Gross photographs from a Cooper’s hawk (Accipiter cooperii)

Gross photographs from a Cooper’s hawk (Accipiter cooperii). (A) Air sac overlying the lung and liver have multiple yellow to green, irregular nodules (arrows). (B) Liver (asterisk) has multiple 1 mm, round to irregular, tan nodules in addition to innumerable miliary foci.

Gross photographs from a Cooper’s hawk (Accipiter cooperii). (A) Air sac overlying the lung and liver have multiple yellow to green, irregular nodules (arrows). (B) Liver (asterisk) has multiple 1 mm, round to irregular, tan nodules in addition to innumerable miliary foci.

Photomicrographs showing lesions in Cooper’s hawk soft palate and lung.
Photomicrographs of Cooper’s hawk soft palate and lung
Photomicrographs of Cooper’s hawk soft palate and lung
Photomicrographs of Cooper’s hawk soft palate and lung

(A) Soft palate of a Cooper’s hawk (Accipiter cooperii). The submucosa is expanded by a myriad of epithelioid macrophages (arrow) surrounding multinucleated giant cells centered on a necrotic center (asterisk). H&E stain. Insert: Intrahistiocytic and extracellular acid-fast bacilli.

(A) Soft palate of a Cooper’s hawk (Accipiter cooperii). The submucosa is expanded by a myriad of epithelioid macrophages (arrow) surrounding multinucleated giant cells centered on a necrotic center (asterisk). H&E stain. Insert: Intrahistiocytic and extracellular acid-fast bacilli.

Healthy elkhorn coral tissue next to elkhorn coral with tissue loss shown by atrophic and thin body wall.
Photomicrograph from a healthy example of elkhorn coral side-by-side with elkhorn coral found with multifocal tissue loss
Photomicrograph from a healthy example of elkhorn coral side-by-side with elkhorn coral found with multifocal tissue loss
Photomicrograph from a healthy example of elkhorn coral side-by-side with elkhorn coral found with multifocal tissue loss

(A) Photomicrograph from a healthy example of elkhorn coral (Acropora palmata). Tall columnar epidermis (E), gastrodermis (g), skeletal space (s), gastrovascular cavity (gvc), and calicodermis (white arrowhead). H&E stain.

(A) Photomicrograph from a healthy example of elkhorn coral (Acropora palmata). Tall columnar epidermis (E), gastrodermis (g), skeletal space (s), gastrovascular cavity (gvc), and calicodermis (white arrowhead). H&E stain.

Photomicrograph at low magnification from elkhorn coral showing flatworm along body wall.
Photomicrograph at low magnification from elkhorn coral (Acropora palmata) found with multifocal tissue loss in the Dominican Republic
Photomicrograph at low magnification from elkhorn coral (Acropora palmata) found with multifocal tissue loss in the Dominican Republic
Photomicrograph at low magnification from elkhorn coral (Acropora palmata) found with multifocal tissue loss in the Dominican Republic

Photomicrograph at low magnification from elkhorn coral (Acropora palmata) found with multifocal tissue loss in the Dominican Republic. A flatworm (fw) is present along a multifocally ulcerated coral surface body wall (c) along one polyp. A small amount of cellular debris can be seen within the pharynx (p) of the flatworm.

Photomicrograph at low magnification from elkhorn coral (Acropora palmata) found with multifocal tissue loss in the Dominican Republic. A flatworm (fw) is present along a multifocally ulcerated coral surface body wall (c) along one polyp. A small amount of cellular debris can be seen within the pharynx (p) of the flatworm.

Photomicrographs of from unknown species of flatworm
Photomicrographs of from unknown species of flatworm
Photomicrographs of from unknown species of flatworm
Photomicrographs of from unknown species of flatworm

Photomicrographs of from unknown species of flatworm. (A) Dorsal detail showing epidermis with rhabdites (black arrowheads) and endosymbionts visible within the flatworm parenchyma (fw).

Photomicrographs of from unknown species of flatworm. (A) Dorsal detail showing epidermis with rhabdites (black arrowheads) and endosymbionts visible within the flatworm parenchyma (fw).

Photographs of elkhorn coral show white portions where tissue loss has occurred.
Photographs from an elkhorn coral colony (Acropora palmata) losing tissue on a reef in the Dominican Republic
Photographs from an elkhorn coral colony (Acropora palmata) losing tissue on a reef in the Dominican Republic
Photographs from an elkhorn coral colony (Acropora palmata) losing tissue on a reef in the Dominican Republic

Photographs from an elkhorn coral colony (Acropora palmata) losing tissue on a reef in the Dominican Republic. (A) Colony in situ with bright white skeleton exposed by multifocal tissue loss (arrowheads) and areas of older tissue loss with algae overgrowth (*).  (B) Submitted samples. Gross lesions are obscured by with loss of pigment with fixation.

Photographs from an elkhorn coral colony (Acropora palmata) losing tissue on a reef in the Dominican Republic. (A) Colony in situ with bright white skeleton exposed by multifocal tissue loss (arrowheads) and areas of older tissue loss with algae overgrowth (*).  (B) Submitted samples. Gross lesions are obscured by with loss of pigment with fixation.

Photographs of Mexican wolf brain showing lesions.
Photographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York
Photographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York
Photographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York

Photographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York, USA. (A) An area of light gray discoloration is present on the surface of the left cranio-dorsal cerebrum (arrow).

Photographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York, USA. (A) An area of light gray discoloration is present on the surface of the left cranio-dorsal cerebrum (arrow).

Photomicrographs from a Mexican Wolf euthanized due to neurologic illness.
Photomicrographs from a Mexican Wolf euthanized due to neurologic illness.
Photomicrographs from a Mexican Wolf euthanized due to neurologic illness.
Photomicrographs from a Mexican Wolf euthanized due to neurologic illness.

Photomicrographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York, USA. (A) Most of the neoplasm consists of loosely arranged, highly vacuolated stellate cells within a variably fine fibrovascular stroma. (B) An area of necrosis (asterisk) surrounded by pseudopalisading neoplastic cells (arrows).

Photomicrographs from a Mexican Wolf (Canis lupus baileyi) euthanized due to neurologic illness in New York, USA. (A) Most of the neoplasm consists of loosely arranged, highly vacuolated stellate cells within a variably fine fibrovascular stroma. (B) An area of necrosis (asterisk) surrounded by pseudopalisading neoplastic cells (arrows).

Photomicrographs from a Mallard Duck with amyloidosis
Photomicrographs of Amyloidosis in a Mallard Duck
Photomicrographs of Amyloidosis in a Mallard Duck
Photomicrographs of Amyloidosis in a Mallard Duck

Photomicrographs from a Mallard Duck (Anas platyrhynchos) found dead in Missouri, U.S.A. (A) The glomerular mesangium (asterisk) is expanded by amorphous, eosinophilic, acellular material. H&E stain. (B) Tubules in medullary cones are often surrounded by amorphous, eosinophilic, acellular material. H&E stain.

Photomicrographs from a Mallard Duck (Anas platyrhynchos) found dead in Missouri, U.S.A. (A) The glomerular mesangium (asterisk) is expanded by amorphous, eosinophilic, acellular material. H&E stain. (B) Tubules in medullary cones are often surrounded by amorphous, eosinophilic, acellular material. H&E stain.

Photos of eastern massasauga rattlesnake showing discolored scales and nodule on lung.
Photographs from an eastern massasauga rattlesnake with snake fungal disease
Photographs from an eastern massasauga rattlesnake with snake fungal disease
Photographs from an eastern massasauga rattlesnake with snake fungal disease

Photographs from an eastern massasauga rattlesnake (Sistrurus catenatus) found lethargic in Wisconsin, U.S.A. (A) There is a 15 x 12 mm area with firm, misshapen, and discolored scales (arrows) on the ventral neck. (B) There is a 10 x 6 focal area of depression with tan to dark red scale discoloration (arrow) on the ventral body.

Photographs from an eastern massasauga rattlesnake (Sistrurus catenatus) found lethargic in Wisconsin, U.S.A. (A) There is a 15 x 12 mm area with firm, misshapen, and discolored scales (arrows) on the ventral neck. (B) There is a 10 x 6 focal area of depression with tan to dark red scale discoloration (arrow) on the ventral body.

Photomicrographs from an eastern massasauga rattlesnake showing necrosis and fungal hyphae.
Photomicrographs from an eastern massasauga rattlesnake (Sistrurus catenatus) from Wisconsin
Photomicrographs from an eastern massasauga rattlesnake (Sistrurus catenatus) from Wisconsin
Photomicrographs from an eastern massasauga rattlesnake (Sistrurus catenatus) from Wisconsin

Photomicrographs from an eastern massasauga rattlesnake (Sistrurus catenatus) from Wisconsin, U.S.A. Periodic acid-Shiff. (A) On the ventral neck are multifocal areas of superficial to mid-epidermal necrosis (arrows). (B) Areas of necrosis often contain ~5-µm diameter branching, septate, PAS-positive fungal hyphae (arrowheads).

Photomicrographs from an eastern massasauga rattlesnake (Sistrurus catenatus) from Wisconsin, U.S.A. Periodic acid-Shiff. (A) On the ventral neck are multifocal areas of superficial to mid-epidermal necrosis (arrows). (B) Areas of necrosis often contain ~5-µm diameter branching, septate, PAS-positive fungal hyphae (arrowheads).

Colony of boulder brain coral with white new tissue loss areas and greenish-brown healthy tissue.
Photographs from a colony of boulder brain coral (Colpophyllia natans) found losing tissue in Biscayne Bay, Miami, Florida
Photographs from a colony of boulder brain coral (Colpophyllia natans) found losing tissue in Biscayne Bay, Miami, Florida
Photographs from a colony of boulder brain coral (Colpophyllia natans) found losing tissue in Biscayne Bay, Miami, Florida

Photographs from a colony of boulder brain coral (Colpophyllia natans) found losing tissue in Biscayne Bay, Miami, FL, US. (A). In situ photograph. An area of prior tissue loss is covered in algal overgrowth (O), new loss is evidenced by white, bare skeleton not yet overgrown by algae (S), and intact healthy-appearing tissue is greenish brown (H).

Photographs from a colony of boulder brain coral (Colpophyllia natans) found losing tissue in Biscayne Bay, Miami, FL, US. (A). In situ photograph. An area of prior tissue loss is covered in algal overgrowth (O), new loss is evidenced by white, bare skeleton not yet overgrown by algae (S), and intact healthy-appearing tissue is greenish brown (H).

Photomicrograph from a boulder brain coral found diseased in Biscayne Bay showing lesions in body wall.
Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida
Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida
Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida

Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, FL, US. There is lytic necrosis of the gastrodermis extending through the surface body wall (asterisk), and mucocyte hyperplasia with loss of gastrodermis from surface and basal body walls (black arrowheads.

Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, FL, US. There is lytic necrosis of the gastrodermis extending through the surface body wall (asterisk), and mucocyte hyperplasia with loss of gastrodermis from surface and basal body walls (black arrowheads.

Photomicrograph from a boulder brain coral found diseased in Biscayne Bay showing lesions in body wall.
Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida
Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida
Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida

Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, FL, US. There is multifocal lytic necrosis of the gastrodermis extending through the surface and basal body walls (asterisks), and mucocyte hyperplasia with loss of gastrodermis from surface and basal body walls (black arrowheads).

Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, FL, US. There is multifocal lytic necrosis of the gastrodermis extending through the surface and basal body walls (asterisks), and mucocyte hyperplasia with loss of gastrodermis from surface and basal body walls (black arrowheads).

Photomicrograph from a boulder brain coral found diseased in Biscayne Bay showing lesions in basal body wall.
Photomicrograph of basal body wall from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida - cloned
Photomicrograph of basal body wall from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida - cloned
Photomicrograph of basal body wall from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, Florida - cloned

Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, FL, US. Within the basal body wall are necrotic “ghost” dinoflagellate endosymbionts with pale eosinophilic cytoplasm, lysis of nucleus, and loss of spherical shape (arrowheads). Normal endosymbionts are circled.

Photomicrograph from a boulder brain coral (Colpophyllia natans) found diseased in Biscayne Bay, FL, US. Within the basal body wall are necrotic “ghost” dinoflagellate endosymbionts with pale eosinophilic cytoplasm, lysis of nucleus, and loss of spherical shape (arrowheads). Normal endosymbionts are circled.