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Publications

Dive into our publications and explore the science from the Environmental Health Program (Toxic Substances Hydrology and Contaminant Biology).

Filter Total Items: 686

Occurrence and spatiotemporal dynamics of pharmaceuticals in a temperate-region wastewater effluent-dominated stream: Variable inputs and differential attenuation yield evolving complex exposure mixtures Occurrence and spatiotemporal dynamics of pharmaceuticals in a temperate-region wastewater effluent-dominated stream: Variable inputs and differential attenuation yield evolving complex exposure mixtures

Effluent-dominated streams are becoming increasingly common in temperate regions and generate complex pharmaceutical mixture exposure conditions that may impact aquatic organisms via drug–drug interactions. Here, we quantified spatiotemporal pharmaceutical exposure concentrations and composition mixture dynamics during baseflow conditions at four sites in a temperate-region effluent...
Authors
Hui Zhi, Dana W. Kolpin, R. D. Klaper, Luke R. Iwanowicz, Shannon M. Meppelink, Gregory H. LeFevre

Hydrocarbons to carboxyl-rich alicyclic molecules: A continuum model to describe biodegradation of petroleum-derived dissolved organic matter in contaminated groundwater plumes Hydrocarbons to carboxyl-rich alicyclic molecules: A continuum model to describe biodegradation of petroleum-derived dissolved organic matter in contaminated groundwater plumes

Relationships between dissolved organic matter (DOM) reactivity and chemical composition in a groundwater plume containing petroleum-derived DOM (DOMHC) were examined by quantitative and qualitative measurements to determine the source and chemical composition of the compounds that persist downgradient. Samples were collected from a transect down the core of the plume in the direction of
Authors
David C. Podgorski, Phoebe Zito, Anne M. Kellerman, Barbara A. Bekins, Isabelle M. Cozzarelli, Donald F. Smith, Xiaoyan Cao, Klaus Schmidt-Rohr, Sasha Wagner, Aron Stubbins, Robert G. M. Spencer

Endocrine and physiological responses of hatchling American kestrels (Falco sparverius) following embryonic exposure to technical short-chain chlorinated paraffins (C10-13) Endocrine and physiological responses of hatchling American kestrels (Falco sparverius) following embryonic exposure to technical short-chain chlorinated paraffins (C10-13)

Short chain chlorinated paraffins (SCCPs) are complex mixtures of polychlorinated n-alkanes, shown to bioaccumulate but with unknown effects in wild birds. The present study examined development-related effects of SCCPs on captive American kestrels (Falco sparverius) treated in ovo on embryonic day (ED) 5 by injection with technical Chloroparaffin® (C10-13, 55.5% Cl) at environmentally...
Authors
Kim J. Fernie, Natalie Karouna-Renier, R. J. Letcher, Sandra L. Schultz, L. E. Peters, V. Palace, Paula F. P. Henry

Endocrine disrupting activities and geochemistry of water resources associated with unconventional oil and gas activity Endocrine disrupting activities and geochemistry of water resources associated with unconventional oil and gas activity

The rise of hydraulic fracturing and unconventional oil and gas (UOG) exploration in the United States has increased public concerns for water contamination induced from hydraulic fracturing fluids and associated wastewater spills. Herein, we collected surface and groundwater samples across Garfield County, Colorado, a drilling-dense region, and measured endocrine bioactivities...
Authors
Christopher D. Kassotis, Jennifer S. Harkness, Phuc H. Vo, Danh C. Vu, Kate Hoffman, Katelyn M. Cinnamon, Jennifer N. Cornelius-Green, Avner Vengosh, Chung-Ho Lin, Donald E. Tillitt, Robin L. Kruse, Jane A. McElroy, Susan C. Nagel

Rapid-assessment test strips: Effectiveness forcyanotoxin monitoring in a northern temperate lake Rapid-assessment test strips: Effectiveness forcyanotoxin monitoring in a northern temperate lake

Precise and rapid methods of determining toxin levels are needed in lakes used for recreation and drinking water to facilitate a quick risk assessment during cyanobacteria blooms. Therefore, we evaluated rapid-assessment test strips, a newer technology for estimating the toxicity of cyanobacterial blooms, in Kabetogama Lake, a popular recreational area of Voyageurs National Park in...
Authors
Jaime F. LeDuc, Victoria Christensen, Ryan P. Maki

Elemental and radionuclide exposures and uptakes by small rodents, invertebrates, and vegetation at active and post-production uranium mines in the Grand Canyon watershed Elemental and radionuclide exposures and uptakes by small rodents, invertebrates, and vegetation at active and post-production uranium mines in the Grand Canyon watershed

The effects of breccia pipe uranium mining in the Grand Canyon watershed (Arizona) on ecological and cultural resources are largely unknown. We characterized the exposure of biota to uranium and co-occurring ore body elements during active ore production and at a site where ore production had recently concluded. Our results indicate that biota have taken up uranium and other elements (e...
Authors
Danielle M. Cleveland, Jo Ellen Hinck, Julia S. Lankton

Biological effects of hydrocarbon degradation intermediates: Is the total petroleum hydrocarbon analytical method adequate for risk assessment? Biological effects of hydrocarbon degradation intermediates: Is the total petroleum hydrocarbon analytical method adequate for risk assessment?

In crude oil contaminant plumes, the dissolved organic carbon (DOC) is mainly hydrocarbon degradation intermediates only partly quantified by the diesel range total petroleum hydrocarbon (TPHd) method. To understand potential biological effects of degradation intermediates, we tested three fractions of DOC: (1) solid-phase extract (HLB); (2) dichloromethane (DCM-total) extract used in...
Authors
Barbara A. Bekins, Jennifer Brennan, Donald E. Tillitt, Isabelle M. Cozzarelli, Jennifer M. Illig, Dalma Martinovich-Weigelt

Ecological forecasting—21st century science for 21st century management Ecological forecasting—21st century science for 21st century management

Natural resource managers are coping with rapid changes in both environmental conditions and ecosystems. Enabled by recent advances in data collection and assimilation, short-term ecological forecasting may be a powerful tool to help resource managers anticipate impending near-term changes in ecosystem conditions or dynamics. Managers may use the information in forecasts to minimize the...
Authors
John B. Bradford, Jake Weltzin, Molly L. McCormick, Jill Baron, Zack Bowen, Sky Bristol, Daren Carlisle, Theresa Crimmins, Paul C. Cross, Joe DeVivo, Mike Dietze, Mary Freeman, Jason Goldberg, Mevin Hooten, Leslie Hsu, Karen Jenni, Jennifer L. Keisman, Jonathan G. Kennen, Kathy Lee, David P. Lesmes, Keith A. Loftin, Brian W. Miller, Peter S. Murdoch, Jana Newman, Karen L. Prentice, Imtiaz Rangwala, Jordan Read, Jennifer Sieracki, Helen Sofaer, Steve Thur, Gordon Toevs, Francisco Werner, C. LeAnn White, Timothy White, Mark T. Wiltermuth

Freshwater neurotoxins and concerns for human, animal, and ecosystemhealth: A review of anatoxin-a and saxitoxin Freshwater neurotoxins and concerns for human, animal, and ecosystemhealth: A review of anatoxin-a and saxitoxin

Toxic cyanobacteria are a concern worldwide because they can adversely affect humans, animals, and ecosystems. However, neurotoxins produced by freshwater cyanobacteria are understudied relative to microcystin. Thus, the objective of this critical review was to provide a comprehensive examination of the modes of action, production, fate, and occurrence of the freshwater neurotoxins...
Authors
Victoria Christensen, Eakalak Khan

Evaluating the potential role of bioactive chemicals on the distribution of invasive Asian carp upstream and downstream from river mile 278 in the Illinois waterway Evaluating the potential role of bioactive chemicals on the distribution of invasive Asian carp upstream and downstream from river mile 278 in the Illinois waterway

Two non-native carp species have invaded the Illinois Waterway and are a threat to Great Lakes ecosystems. Poor water quality in the upper Illinois Waterway, may be a factor contributing to the stalling of the carp population front near river mile 278. In 2015, the U.S. Geological Survey collected 4 sets of water samples from two sites upstream and 4 sites downstream from river mile 278...
Authors
William A. Battaglin, James J. Duncker, Paul J. Terrio, Paul M. Bradley, Larry B. Barber, Laura A. DeCicco

Compositional analysis of formation water geochemistry and microbiology of commercial and carbon dioxide-rich wells in the southwestern United States Compositional analysis of formation water geochemistry and microbiology of commercial and carbon dioxide-rich wells in the southwestern United States

Studies of naturally occurring subsurface carbon dioxide (CO2) accumulations can provide useful information for potential CO2 injection projects; however, the microbial communities and formation water geochemistry of most reservoirs are understudied. Formation water and microbial biomass were sampled at four CO2-rich reservoir sites: two within Bravo Dome, a commercial CO2 field in New...
Authors
Jenna L. Shelton, Robert S. Andrews, Denise M. Akob, Christina A. DeVera, Adam C. Mumford, Mark Engle, Michelle R. Plampin, Sean T. Brennan

Factors affecting sampling strategies for design of an effects‐directed analysis for endocrine‐active chemicals Factors affecting sampling strategies for design of an effects‐directed analysis for endocrine‐active chemicals

Effects‐directed analysis (EDA) is an important tool for identifying unknown bioactive components in a complex mixture. Such an analysis of endocrine‐active chemicals (EACs) from water sources has promising regulatory implications but also unique logistical challenges. We propose a conceptual EDA (framework) based on a critical review of EDA literature and concentrations of common EACs...
Authors
Jennifer Brennan, Robert W. Gale, David A. Alvarez, Jason P. Berninger, Jessica Kristin Leet, Yan Li, Tyler Wagner, Donald E. Tillitt
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