Since 2006, we have partnered with agencies around the world to monitor the spread of highly pathogenic (HPAI) avian influenza. In 2014, our scientists detected three HPAI viruses for the first time in wild birds in North America: H5N2, H5N8, and a recombinant H5N1. In response to HPAI detections, our scientists are working closely with the U.S. Department of Agriculture and other Federal and state agency partners.
Avian malaria is a mosquito-borne bird disease caused by a protozoan parasite (Plasmodium relictum). P. relictum reproduces in avian red blood cells. If the parasite load is sufficiently high, the bird loses red blood cells (anemia). Because red blood cells are critical for moving oxygen about the body, loss of these cells can lead to progressive weakness and, eventually, death. This disease was introduced to Hawaii and native honeycreepers are highly susceptible.
Avian botulism is caused by the soil bacterium, Clostridium botulinum, and causes paralysis and death in birds. Two types of botulism have been found in birds: Type C, which occurs during warmer months across the U.S., and Type E, which is found primarily in the Great Lakes.
Avian Influenza Geonarrative

Avian influenza viruses occur naturally in wild birds such as ducks, geese, swans, and gulls. These viruses generally do not cause illness in wild birds but they can be highly pathogenic and cause illness and death in poultry and wildlife. Learn more with this geonarrative.
Avian Disease Research
Distribution of Highly Pathogenic Avian Influenza in North America, 2021/2022
Avian Influenza Surveillance
Avian Malaria Genomic Research Project
New Technologies and Groundwork for Mosquito Control in the Alakai Plateau
Antibiotic Resistant Bacteria in Migratory Birds
Avian Influenza
Avian Botulism
Toxoplasmosis
Avian Ecology and Multi-Species Habitat Use in Pacific Coast Estuaries
Avian Diseases
Avian Pathogens and Vectors - Kahuku Unit of Hawaii Volcanoes National Park
Efficacy of Avian Botulism Surveillance and Mitigation Using Detection Canines
Recent data (2020-2022) related to USGS avian disease research is listed below. A complete listing of USGS avian disease data is available from the button below.
Data describing infection status and movement ecology of North American waterfowl
Spatial models indicating avian influenza transmission risk at the interface of domestic poultry and wild birds in China
Data measuring avian influenza infection, mercury concentration, and body condition in wild waterfowl
Weekly estimates of the risk of avian influenza transmission from wild waterfowl to domestic poultry - Initial phase models
Relative susceptibility of poultry to the transmission of Avian Influenza from wild birds based upon poultry type and density
Telemetry data of a Lesser Scaup (Aythya affinis) positive for 2.3.4.4 Highly Pathogenic H5N1
Spatial Models of Wild Bird Risk Factors for Highly Pathogenic A(H5N1) Avian Influenza Virus Transmission
Dataset: Surveillance for Avian Influenza Virus in Iceland, 2010 - 2018
Data concerning maintenance and dissemination of avian-origin influenza A virus within the Northern Atlantic Flyway of North America
Predicted Avian Influenza Prevalence for Wild Waterfowl Species Across the Continental United States.
Locations of Pacific Flyway Ducks in and near Commercial Livestock Facilities of the Western USA (2015-2021)
Temporal Viral Viability Data from Avian Influenza A Viruses Maintained in Alaska Wetlands Under Experimental and Environmental Conditions
Recent publications (2020-2022) related to USGS avian disease research are listed below. A complete listing of USGS avian disease publications is available from the button below.
Avian influenza antibody prevalence increases with mercury contamination in wild waterfowl
Spatiotemporal changes in influenza A virus prevalence among wild waterfowl inhabiting the continental United States throughout the annual cycle
Proceedings of the Highly Pathogenic Avian Influenza and Wild Birds Webinar Series, August 2–5, 2021
Host plant associations of Lepidoptera and implications for forest bird management at Hakalau Forest National Wildlife Refuge
Highly pathogenic avian influenza (HPAI): An emerging disease threat in North America
Maintenance and dissemination of avian-origin influenza A virus within the northern Atlantic Flyway of North America
Ecological divergence of wild birds drives avian influenza spillover and global spread
Hawaiian forest bird conservation strategies for minimizing the risk of extinction: biological and biocultural considerations
Highly pathogenic avian influenza is an emerging disease threat to wild birds in North America
Pathways for avian influenza virus spread: GPS reveals wild waterfowl in commercial livestock facilities and connectivity with the natural wetland landscape
Host correlates of avian influenza virus infection in wild waterfowl of the Sacramento Valley, California
Using the California Waterfowl Tracker to assess proximity of waterfowl to commercial poultry in the Central Valley of California
Explore our science using the interactive tools below.
Avian Influenza Geonarrative
The USGS Ecosystems Mission Area provides science to understand wildlife diseases, including avian influenza (AI). Avian influenza viruses occur naturally in wild birds such as ducks, geese, swans, and gulls. These viruses generally do not cause illness in wild birds but they can be highly pathogenic and cause illness and death in poultry and wildlife. Learn more with this geonarrative.
Story Map: Avian Influenza in the United States
This story map explores the role USGS scientists play in understanding the risks presented by avian influenza, and how their work is being used to predict areas of transmission risk.
Visualizing Models for Avian Influenza Viruses
Emergence of avian influenza viruses with the potential to be highly pathogenic to poultry, wild birds, & humans, such as the highly pathogenic H5N1 and H7N9 cause serious concern for the global economic & public health sectors. Visual representations of model data can be effective in helping to discover how the spread of the virus is influenced by environmental & human
- Overview
Since 2006, we have partnered with agencies around the world to monitor the spread of highly pathogenic (HPAI) avian influenza. In 2014, our scientists detected three HPAI viruses for the first time in wild birds in North America: H5N2, H5N8, and a recombinant H5N1. In response to HPAI detections, our scientists are working closely with the U.S. Department of Agriculture and other Federal and state agency partners.
Avian malaria is a mosquito-borne bird disease caused by a protozoan parasite (Plasmodium relictum). P. relictum reproduces in avian red blood cells. If the parasite load is sufficiently high, the bird loses red blood cells (anemia). Because red blood cells are critical for moving oxygen about the body, loss of these cells can lead to progressive weakness and, eventually, death. This disease was introduced to Hawaii and native honeycreepers are highly susceptible.
Avian botulism is caused by the soil bacterium, Clostridium botulinum, and causes paralysis and death in birds. Two types of botulism have been found in birds: Type C, which occurs during warmer months across the U.S., and Type E, which is found primarily in the Great Lakes.
Avian Influenza GeonarrativeAvian influenza viruses occur naturally in wild birds such as ducks, geese, swans, and gulls. These viruses generally do not cause illness in wild birds but they can be highly pathogenic and cause illness and death in poultry and wildlife. Learn more with this geonarrative.
Avian Disease ResearchFilter Total Items: 17Distribution of Highly Pathogenic Avian Influenza in North America, 2021/2022
The first 2021/2022 detection of Eurasian strain (EA) highly pathogenic avian influenza (HPAI) H5N1 in North America occurred in December 2021 in Newfoundland and Labrador, Canada. Subsequently, HPAI EA H5 and EA H5N1 viruses have been confirmed in wild birds, backyard flocks, commercial poultry facilities, and wild mammals in both Canada and the United States. This HPAI distribution map will be...Avian Influenza Surveillance
The USGS National Wildlife Health Center (NWHC) conducts surveillance in wild birds to facilitate early detection and situational awareness for high consequence pathogens, including highly pathogenic avian influenza (HPAI) viruses.Avian Malaria Genomic Research Project
Many factors including habitat destruction, invasive plants, non-native predators and competitors, and introduced diseases have decimated the diverse, endemic native forest bird community of Hawai‘i. In particular, avian malaria (Plasmodium relictum), which is transmitted by the introduced Southern House Mosquito (Culex quinquefasciatus), has caused dramatic declines and extinctions in many native...New Technologies and Groundwork for Mosquito Control in the Alakai Plateau
Introduced mosquito-borne avian diseases, avian pox and avian malaria, are key limiting factors for endemic Hawaiian forest birds and are, in part, likely responsible for past extinctions and the continued decline of extant species populations. In the last 40 years on the island of Kaua‘i a number of species have become increasingly rare and several are now presumed extinct. Coinciding with these...Antibiotic Resistant Bacteria in Migratory Birds
Migratory birds, and particularly those using habitats close to human settlements, may be infected with antibiotic resistant bacteria. The USGS is working with public health professionals to understand the role of birds in the maintenance and dispersal of antibiotic resistant bacteria. Additionally, the USGS is investigating how antibiotic resistant bacteria in birds may relate to public and...Avian Influenza
Avian influenza is a viral disease caused by various strains of avian influenza viruses that can be classified as low pathogenic avian influenza (LPAI) or highly pathogenic avian influenza (HPAI). It remains a global disease with potential high consequence with the potential to threaten wildlife, agriculture, and human health.Avian Botulism
Botulism is a natural toxin produced by a bacterium ( Clostridium botulinum ) commonly found in the soil. There are several types of botulism toxin some of which can affect humans who eat improperly canned foods. Birds get their own kind of botulism (Type C in Hawaii) that does not affect humans. Botulism type C is concentrated in aquatic invertebrates that filter feed sediments or water. When...Toxoplasmosis
Toxoplasmosis is caused by a microscopic parasites called a protozoan. The specific name of the protozoan that causes toxoplasmosis is Toxoplasma gondii. T. gondii reproduces in the gut of cats (all members of the Felidae are susceptible). Cats shed the parasite in their feces, and the parasite is ingested by other animals (intermediate hosts) causing disease. Cats can acquire the parasite from...Avian Ecology and Multi-Species Habitat Use in Pacific Coast Estuaries
Waterbirds such as shorebirds, waders, and ducks depend on healthy and productive estuaries to “fuel up” for long distance migrations along the Pacific Flyway. Estuarine ecosystems include a mosaic of managed, natural, and restoring wetlands, and provide critical stop-over and wintering areas for federally protected migratory bird species. USGS WERC’s Dr. Susan De La Cruz works with federal, state...Avian Diseases
The Honolulu Field Station provides routine diagnostic support to state and federal agencies in order to determine cause of death in endangered and threatened native birds in Hawaii, US territories, and affiliated states in the Pacific. These activities have resulted in information that was important in the recovery of several species of endangered birds such as Laysan ducks, Nihoa millerbirds...Avian Pathogens and Vectors - Kahuku Unit of Hawaii Volcanoes National Park
While the Hawaiian avian disease system has been well-studied in the forests of the older section of Hawai‘i Volcanoes National Park (HAVO), and in many other locations throughout the state, nothing was known about avian disease in the new Kahuku Unit of Hawai‘i Volcanoes National Park and the adjacent Kau Forest Reserve. The high elevation forests of Kahuku are the only habitat located on...Efficacy of Avian Botulism Surveillance and Mitigation Using Detection Canines
Avian botulism causes waterbird mortality in Hawai‘i's wetlands and elsewhere. We will evaluate using trained scent-detection canines (sniffer dogs) as a new tool to survey for the presence of avian botulism. Biologists will compare variables influencing detection probability and detection rates with traditional search methods. The pilot study will test the feasibility of this approach as a new... - Data
Recent data (2020-2022) related to USGS avian disease research is listed below. A complete listing of USGS avian disease data is available from the button below.
Filter Total Items: 19Data describing infection status and movement ecology of North American waterfowl
These data, which support a USGS authored manuscript, describe how active and previous previous infection with avian influenza impacts the movement ecology of several wild waterfowl species that overwinter in California. Results varied by species and demonstrate that the relationships between avian influenza infection and wild bird movements are context- and species-dependent.Spatial models indicating avian influenza transmission risk at the interface of domestic poultry and wild birds in China
Emergence of avian influenza viruses with high lethality to humans, such as the currently circulating highly pathogenic A(H5N1) and A(H7N9) cause serious concern for the global economic and public health sectors. To improve our understanding of the spatial and temporal trends in transmission risk we developed a model that predicts hotspots of novel virus emergence between domestic and wild birds aData measuring avian influenza infection, mercury concentration, and body condition in wild waterfowl
These data represent mercury contamination, influenza infection, and body condition in 11 species of dabbling and diving ducks in the Pacific Flyway. These data support a USGS lead scientific publication.Weekly estimates of the risk of avian influenza transmission from wild waterfowl to domestic poultry - Initial phase models
This data layer depicts the weekly estimates of the relative risk of avian influenza transmission from wild waterfowl to domestic poultry. These data represent an early phase of ongoing model development and the inclusion of additional parameters is upcoming.Relative susceptibility of poultry to the transmission of Avian Influenza from wild birds based upon poultry type and density
This data layer depicts the relative susceptibility of poultry to the transmission of Avian Influenza from wild birds based upon poultry type and density for the contiguous United States.Telemetry data of a Lesser Scaup (Aythya affinis) positive for 2.3.4.4 Highly Pathogenic H5N1
Wild lesser scaup from the Chesapeake Bay, captured and implanted with satellite transmitters for a separate ecology study, were opportunistically sampled for avian influenza. These data detail the virological sampling results, obtained post release, which include a single positive for clade 2.3.4.4 H5N1 virus of the A/goose/Guangdong/1/1996 (Gs/GD) H5N1 lineage of highly pathogenic IAV. These datSpatial Models of Wild Bird Risk Factors for Highly Pathogenic A(H5N1) Avian Influenza Virus Transmission
Wild waterfowl (family Anatidae) are reported as secondary transmitters of HPAIV and primary reservoirs for low-pathogenic avian influenza viruses, yet spatial inputs for disease risk modeling for this group have been lacking. Using geographic information software and Monte Carlo simulations, we developed geospatial indices of waterfowl abundance at 1 km resolutions for the breeding and winteringDataset: Surveillance for Avian Influenza Virus in Iceland, 2010 - 2018
From 2010-2018 we investigated the occurrence of avian influenza virus in wild birds in Iceland. A total of 6635 swabs samples were collected from wild birds or fecal material directly associated with wild birds. We screened all samples by a real time - polymerase chain reaction (RT-PCR) test with 381 testing positive. Further testing of all RT-PCR positive samples and all negative samples collectData concerning maintenance and dissemination of avian-origin influenza A virus within the Northern Atlantic Flyway of North America
This data release details the results of avian influenza sampling of dabbling ducks in Maine and Maryland. These data support an associated USGS publication.Predicted Avian Influenza Prevalence for Wild Waterfowl Species Across the Continental United States.
This data release provides the predicted proportion of birds testing positive for IAV for each species at weekly intervals for each county centroid in the continental United States. This data supports a paired USGS publication.Locations of Pacific Flyway Ducks in and near Commercial Livestock Facilities of the Western USA (2015-2021)
Zoonotic diseases are of considerable concern to the human population and viruses such as avian influenza (AIV) threaten food security, wildlife conservation and human health. Wild waterfowl and the natural wetlands they use, are known AIV reservoirs, with birds capable of virus transmission to domestic poultry populations. While infection risk models have linked migration routes and AIV outbreaksTemporal Viral Viability Data from Avian Influenza A Viruses Maintained in Alaska Wetlands Under Experimental and Environmental Conditions
Data sets containing: (1) sample collection and influenza A virus (IAV) screening information for wild ducks, (2) water temperature data from four wetlands within the Izembek National Wildlife Refuge in Alaska, USA (3) water quality measurement from four wetlands within the Izembek National Wildlife Refuge in Alaska, USA, (4) genetic sequence data for IAVs recovered from replicate samples of wild - Publications
Recent publications (2020-2022) related to USGS avian disease research are listed below. A complete listing of USGS avian disease publications is available from the button below.
Filter Total Items: 37Avian influenza antibody prevalence increases with mercury contamination in wild waterfowl
Environmental contamination is widespread and can negatively impact wildlife health. Some contaminants, including heavy metals, have immunosuppressive effects, but prior studies have rarely measured contamination and disease simultaneously, which limits our understanding of how contaminants and pathogens interact to influence wildlife health. Here, we measured mercury concentrations, influenza infSpatiotemporal changes in influenza A virus prevalence among wild waterfowl inhabiting the continental United States throughout the annual cycle
Avian influenza viruses can pose serious risks to agricultural production, human health, and wildlife. An understanding of viruses in wild reservoir species across time and space is important to informing surveillance programs, risk models, and potential population impacts for vulnerable species. Although it is recognized that influenza A virus prevalence peaks in reservoir waterfowl in late summeProceedings of the Highly Pathogenic Avian Influenza and Wild Birds Webinar Series, August 2–5, 2021
In light of ongoing and geographically widespread highly pathogenic avian influenza (HPAI) outbreaks in wild birds throughout much of Eurasia during 2020–21, the Interagency Steering Committee for Avian Influenza Surveillance in Wild Migratory Birds disseminated an informational memorandum in January 2021 to highlight the need for enhanced surveillance and heightened awareness in North America. ThHost plant associations of Lepidoptera and implications for forest bird management at Hakalau Forest National Wildlife Refuge
Forests dominated or co-dominated by ‘ōhi‘a (Metrosideros polymorpha) are critical to most Hawaiian forest birds, but fungal diseases causing Rapid ‘Ōhi‘a Death (ROD) threaten ‘ōhi‘a-based food webs that support native bird communities on Hawai‘i Island. Caterpillars are the most frequently consumed arthropod prey of native birds and their young and are especially frequent in the diets of one threHighly pathogenic avian influenza (HPAI): An emerging disease threat in North America
Highly pathogenic avian influenza (HPAI) is an ecologically and economically significant avian disease that is quickly spreading among wild and domestic birds throughout North America. In this blog post, we provide information and resources that can help you to be informed, be prepared, and be ready to take appropriate action should you observe wild birds that may be affected by HPAI.Maintenance and dissemination of avian-origin influenza A virus within the northern Atlantic Flyway of North America
Wild waterbirds, the natural reservoirs for avian influenza viruses, undergo migratory movements each year, connecting breeding and wintering grounds within broad corridors known as flyways. In a continental or global view, the study of virus movements within and across flyways is important to understanding virus diversity, evolution, and movement. From 2015 to 2017, we sampled waterfowl from breeEcological divergence of wild birds drives avian influenza spillover and global spread
The diversity of influenza A viruses (IAV) is primarily hosted by two highly divergent avian orders: Anseriformes (ducks, swans and geese) and Charadriiformes (gulls, terns and shorebirds). Studies of IAV have historically focused on Anseriformes, specifically dabbling ducks, overlooking the diversity of hosts in nature, including gull and goose species that have successfully adapted to human habiHawaiian forest bird conservation strategies for minimizing the risk of extinction: biological and biocultural considerations
The iconic forest birds of Hawai‘i are facing a conservation crisis. Across the Hawaiian Islands, native forest birds have been experiencing population declines that have accelerated in the last one to two decades. While habitat loss, invasive species, and non-native predators have negatively affected forest bird species for hundreds of years, and continue to do so, introduced diseases, particularHighly pathogenic avian influenza is an emerging disease threat to wild birds in North America
Prior to the emergence of the A/goose/Guangdong/1/1996 (Gs/GD) H5N1 influenza A virus, the long-held and well-supported paradigm was that highly pathogenic avian influenza (HPAI) outbreaks were restricted to poultry, the result of cross-species transmission of precursor viruses from wild aquatic birds that subsequently gained pathogenicity in domestic birds. Therefore, management agencies typicallPathways for avian influenza virus spread: GPS reveals wild waterfowl in commercial livestock facilities and connectivity with the natural wetland landscape
Zoonotic diseases are of considerable concern to the human population and viruses such as avian influenza (AIV) threaten food security, wildlife conservation and human health. Wild waterfowl and the natural wetlands they use are known AIV reservoirs, with birds capable of virus transmission to domestic poultry populations. While infection risk models have linked migration routes and AIV outbreaks,Host correlates of avian influenza virus infection in wild waterfowl of the Sacramento Valley, California
Avian influenza viruses (AIVs) are distributed globally in members of the family Anatidae (waterfowl), and significant disease may occur when these viruses infect commercial poultry or humans. Early detection of AIV through surveillance of wild waterfowl is one measure to prevent future disease outbreaks. Surveillance efforts that are designed to account for host and environmental determinants ofUsing the California Waterfowl Tracker to assess proximity of waterfowl to commercial poultry in the Central Valley of California
Migratory waterfowl are the primary reservoir of avian influenza viruses (AIV) which can be spread to commercial poultry. Surveillance efforts that track the location and abundance of wild waterfowl and link those data to inform assessments of risk and sampling for AIV currently do not exist. To assist surveillance and minimize poultry exposure to AIV, here we explored the utility of remotely sens - Web Tools
Explore our science using the interactive tools below.
Avian Influenza Geonarrative
The USGS Ecosystems Mission Area provides science to understand wildlife diseases, including avian influenza (AI). Avian influenza viruses occur naturally in wild birds such as ducks, geese, swans, and gulls. These viruses generally do not cause illness in wild birds but they can be highly pathogenic and cause illness and death in poultry and wildlife. Learn more with this geonarrative.
ByEcosystems Mission Area, Biological Threats and Invasive Species Research Program, Cooperative Research Units, Fish & Wildlife Disease (unpublished), Alaska Science Center, Eastern Ecological Science Center, National Wildlife Health Center, Upper Midwest Environmental Sciences Center, Upper Midwest Water Science Center, Western Ecological Research Center (WERC)Story Map: Avian Influenza in the United States
This story map explores the role USGS scientists play in understanding the risks presented by avian influenza, and how their work is being used to predict areas of transmission risk.
Visualizing Models for Avian Influenza Viruses
Emergence of avian influenza viruses with the potential to be highly pathogenic to poultry, wild birds, & humans, such as the highly pathogenic H5N1 and H7N9 cause serious concern for the global economic & public health sectors. Visual representations of model data can be effective in helping to discover how the spread of the virus is influenced by environmental & human