Environmental Toxicology

The USGS Environmental Health Program seeks to understand how environmental factors, especially contaminants and pathogens, influence human health and ecosystems. It focuses on studying the distribution and effects of toxic substances, environmental stressors, and their pathways. The program prioritizes collaboration with State, Federal and local governments; Tribes; non-government organizations...

Critical minerals are essential to the Nation’s economy and security. Demand for critical minerals is increasing, and it is essential to balance the societal need for these minerals with efforts to understand the effects of mining on other natural resources and to develop techniques to minimize these effects. The USGS Minerals Resources Life Cycle Integrated Science Team (IST) focuses on the life...

The team studies the movement of toxicants and pathogens that could originate from the growing, raising, and processing/manufacturing of plant and animal products through the environment where exposure can occur. This information is used to understand if there are adverse effects upon exposure and to develop decision tools to protect health.

The Immunomodulation Integrated Science Team focuses on contaminant and pathogen exposures in the environment that might influence the immune systems of wildlife and the connection to their shared environment with humans. In collaboration with public-health officials, the Team also addresses potential human-health risks stemming from similar exposures. If actual risks are identified, this Team...

U.S. Geological Survey (USGS) scientists investigated the movement of human-generated chemicals, such as pharmaceuticals and per- and polyfluorinated substances (PFAS), in groundwater along the South Rim of the Grand Canyon. This research led to a better understanding of the movement of wastewater into groundwater, of complex underground flow patterns, and of chemicals present in springs near...

About the Research. The Environmental Health Program supports scientists in the Behavioral Toxicology Core Technology Team (CTT) at the Columbia Environmental Research Center. The scientists identify how contaminants alter the behavior of organisms and what implication those changes may have on individuals, populations, and communities.

About the Research The Photomicroscopy and Flow Cytometry Core Technology Team (CTT) as part of the Environmental Health Program works to develop and apply biomarkers to evaluate the potential impacts of environmental contaminants at cellular and molecular levels. Because molecular and biochemical responses of cells are preceded by chemical changes in nuclei, cytoplasm, membranes, and...

About the Research The Functional and Molecular Bioassay Core Technology Team (CTT) as part of the Environmental Health Program utilizes reporter assays, quantitative gene expression analyses, and high-throughput sequencing methods to produce functional endpoints across a broad scope of environmental topics and sample matrices.

The team studies toxicants and pathogens in water resources from their sources, through watersheds, aquifers, and infrastructure to human and wildlife exposures. That information is used to develop decision tools that protect human and wildlife health.

Increasing scientific and public awareness of the widespread distribution of per- and poly-fluoroalkyl substances (PFAS) in U.S. drinking-water supplies, aquatic and terrestrial ecosystems, wildlife, and humans has raised many public health and resource management questions that U.S. Geological Survey's (USGS) science can inform. The USGS Environmental Health Program's PFAS Integrated Science Team...

The team is determining the movement and behavior of per- and poly-fluoroalkyl substances (PFAS) from their sources in the environment, as they move through exposure pathways in ecosystems including watersheds and aquifers, their incorporation into food webs, and molecular to population scale effects on fish and wildlife. These studies are accomplished at a variety of spatial scales from regional...

The Ecologically-Driven Exposure Pathways Integrated Science Team identifies how ecological pathways and physiological processes within a single organism can alter exposure and toxicity of contaminants and pathogens and seek to understand outcomes at different scales from individuals to populations and ecosystems.