Immunomodulation Science Team
Immunomodulation Science Team
The Immunomodulation Integrated Science Team focuses on contaminant and pathogen exposures in the environment that might influence the immune systems of wildlife and the connection to their shared environment with humans.
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Exploring the Sensitivity of Salmonids to 6PPD-Quinone: Implications for Urban Ecosystems
The USGS is investigating the effects of 6PPD-quinone (6PPDQ), a harmful contaminant found in urban stormwater runoff, on fish and wildlife health, particularly in salmonids. Recent studies have shown that 6PPDQ poses acute toxicity risks, especially to coho salmon, with sensitivity varying by life stage. New research evaluated the lethal and sublethal impacts of 6PPDQ exposure on coastal...
USGS Environmental Health Program: Integrating Science for Public Health and Resource Management
The USGS Environmental Health Program seeks to understand how environmental factors, especially contaminants and pathogens, influence human health and ecosystems. It focuses on studying the distribution and effects of toxic substances, environmental stressors, and their pathways. The program prioritizes collaboration with State, Federal and local governments; Tribes; non-government organizations...
USGS Research on 6PPD-quinone: Where the Rubber Meets the Road
Stormwater and road runoff are recognized forms of pollution that can contain chemicals harmful to fish and other aquatic animals. This includes 6PPD-quinone, the oxidized form of the chemical compound 6PPD that is used to prevent tires from degrading and cracking, ensuring driver safety. As 6PPD-quinone sheds from tires during normal wear it can enter streams in stormwater runoff.
Immunomodulation Science Team
The Immunomodulation Integrated Science Team focuses on contaminant and pathogen exposures in the environment that might influence the immune systems of wildlife and the connection to their shared environment with humans. In collaboration with public-health officials, the Team also addresses potential human-health risks stemming from similar exposures. If actual risks are identified, this Team...
Per- and Polyfluoroalkyl Substance (PFAS) Core Technology Team
The Per- and Polyfluoroalkyl Substance (PFAS) Core Technology Team (CTT) within the Environmental Health Program partners with external and internal stakeholders to develop and apply analytical methods for measuring PFAS in complex matrices, addressing environmental health issues related to transport, distribution, fate, effects, and exposure.
Preliminary Research Sheds Light on Proper Analysis and Sample Handling for the Tire-Derived Contaminants 6PPD and 6PPD-quinone
Tire and road wear particles have been shown to cause acute effects to sensitive aquatic animals and degrade their habitats. U.S. Geological Survey (USGS) scientists developed methods to accurately identify aquatic compounds, such as 6PPD and 6PPD-quinone, that can cause acute mortality events in coho salmon (Oncorhynchus kisutch).
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Ecosystems Mission Area, Contaminant Biology, Environmental Health Program, Toxic Substances Hydrology, Central Midwest Water Science Center, Eastern Ecological Science Center, Kansas Water Science Center, New Jersey Water Science Center, Oklahoma-Texas Water Science Center, South Atlantic Water Science Center (SAWSC), Washington Water Science Center, Western Fisheries Research Center
6PPD-quinone
6PPD-quinone is a compound used to make tires more durable and is also linked to toxicity for Coho Salmon and other aquatic species.