Dr. Barnett Rattner is an ecotoxicologist at the Eastern Ecological Science Center in Laurel, MD.
He conducts hypothesis-driven laboratory and field investigations, risk assessments and scholarly evaluations on the toxicity of legacy and contemporary pollutants (industrial contaminants, metals, pesticides, petroleum crude oil) to wildlife and the environment. His current focus is on exposure and adverse effects of anticoagulant rodenticides, flame retardants and pharmaceuticals, comparative toxicology, non-target secondary poisoning associated with rodenticides, alternative testing methods, and screening-level risk assessments. Dr. Rattner actively represents the DOI as a member of the Interagency Coordinating Committee on the Validation of Alternative Methods, and serves as a special consultant to the Fish and Wildlife Service on issues related to nontoxic shot used in hunt nontoxic shot used in hunt waterfowl.
Active Projects:
- Development of data and models to evaluate the hazard and risk of anticoagulant rodenticides to non-target raptorial species
- Absorption, distribution, metabolism, elimination and toxicity of neonicotinoids in seed-eating birds
- Harmful algal blooms and bird die-offs in the Chesapeake Bay: A potential link?
- Contaminant exposure and potential reproductive effects in ospreys nesting in Chesapeake and Delaware Bay
- Contaminant-related activities and synoptic reviews in support of client agencies in the Department of the Interior
- Technical assistance to the Fish and Wildlife Service on alternative shot
Accomplishments:
- Authored over 135 publications, co-edited three books (Handbook of Ecotoxicology, Ecotoxicology of Wild Mammals, Anticoagulant Rodenticides and Wildlife), and made over 160 presentations at scientific meetings, workshops and symposia.
- Compiled two widely used internet-accessible ecotoxicological databases (Contaminant Exposure and Effects—Terrestrial Vertebrates database, Biological and Ecotoxicological Characteristics of Terrestrial Vertebrate Species Residing in Estuaries).
- Serves as Terrestrial Editor of Environmental Toxicology and Chemistry, and as an Editorial Board member of the Bulletin of Environmental Contamination and Toxicology, and Outlooks on Pest Management.
Professional Experience
Ecotoxicologist and Physiologist (research scientist, section leader, deputy branch chief) Department of the Interior, FWS, NBS, and USGS (1978-present)
Adjunct Professor University of Maryland, Department of Animal and Avian Sciences & Department of Environmental Science and Technology (1988-2022)
National Research Council Post-doctoral Research Associate, National Naval Medical Center (1978
Guest Worker, National Institute of Arthritis, Metabolism and Digestive and Kidney Diseases, NIH (1974-1981)
Instructor and Graduate Teaching Assistant, University of Maryland, Department of Zoology (1972-1977)
Education and Certifications
B.S., University of Maryland, 1972 - Zoology
M.S., University of Maryland, 1974 - Zoology, Developmental Biology
Ph.D., University of Maryland, 1977 - Zoology, Environmental Physiology
National Research Council Postdoctoral Associateship, Naval Medical Research Institute, 1978 - Hyperbaric Physiology
Affiliations and Memberships*
Society of Environmental Toxicology and Chemistry
Society of Toxicology
The Wildlife Society
American Physiological Society
Honors and Awards
Distinguished Service Award, Department of the Interior 2018
Fellow, Society of Environmental Toxicology and Chemistry 2017
President, Society of Environmental Toxicology and Chemistry World Council 2015
President, Society of Environmental Toxicology and Chemistry - North America 2012
SETAC Government Service Award 2007
Science and Products
Review of Wildlife Health Outcomes and Potentially Toxic Algal Blooms in the Chesapeake Bay
Scientists Provide an Understanding of Anticoagulant Rodenticide Exposure in Non-Target Bird Species
Hazard and Risk of Anticoagulant Rodenticides to Predatory and Scavenging Wildlife
Do pesticide coatings on agricultural seeds pose a threat to earthworms and to the birds that eat them?
Whole Wildlife Toxicology Catalog
No Evidence of Toxicity to Birds Ingesting Neonicotinoid-Coated Wheat Seeds During Controlled Laboratory Study
Contaminant-related Activities in Support of Client Agencies in the Department of the Interior
Contaminant Exposure, Food Web Transfer and Potential Health Effects on Chesapeake Bay and Delaware Bay Waterbirds
Long-term Studies Examine Contaminant Exposure and Reproduction of Ospreys Nesting in Two Large United States Estuaries
Genomic and Behavioral Effects of the Neonicotinoid Imidacloprid in Birds Exposed Through Pesticide-Coated Seeds
Assessing Contaminant Hazards Without a Critter—Advancements in Alternatives to Animal Toxicity Testing
Do Neonicotinoid Pesticide Seed Coatings Pose a Hazard to Seed-eating Birds?
Breeding songbird tissue analysis and metal concentrations in tissues, soil and invertebrates collected near nesting sites within the Southeast Missouri Lead Mining District, 2016-19
The Contaminant Exposure and Effects-Terrestrial Vertebrates database (CEE-TV)
Toxicological responses to sublethal anticoagulant rodenticide exposure in free-flying red-tailed hawks
Assessing Exposure, Physiological Effects, and Geographic Scope of Anticoagulant Rodenticides in the Critically Endangered California Condor
Great Blue Heron collection at Poplar Island Complex and Chesapeake Marshlands National Wildlife Refuge Complex
Toxicokinetics of imidacloprid-coated wheat seeds in Japanese quail (Coturnix coturnix) and an assessment of risk
Use of blood clotting assays to assess anticoagulant rodenticide exposure and effects in free-ranging birds of prey
Examination of contaminant exposure and reproduction of ospreys (Pandion haliaetus) nesting in Delaware Bay and River in 2015
Investigation of pharmaceuticals in water, fish, and ospreys nesting in Delaware River and Bay
Effects of lead exposure on birds breeding in the Southeast Missouri Lead Mining District
Wildlife ecological risk assessment in the 21st century: Promising technologies to assess toxicological effects
Toxicological effects assessment for wildlife in the 21st Century: Review of current methods and recommendations for a path forward
Preliminary evidence of anticoagulant rodenticide exposure in American kestrels (Falco sparverius) in the western United States
Do pharmaceuticals in the environment pose a risk to wildlife?
Drivers of Pb, Sb and As release from spent gunshot in wetlands: Enhancement by organic matter and native microorganisms
Collateral damage: Anticoagulant rodenticides pose threats to California condors
Toxicological responses to sublethal anticoagulant rodenticide exposure in free-flying hawks
A critical review of bioaccumulation and biotransformation of organic chemicals in birds
Exposure of predatory and scavenging birds to anticoagulant rodenticides in France: Exploration of data from French surveillance programs
Measuring U.S. Federal Agency progress toward implementation of alternative methods in toxicity testing
Evaluating a rapid field assessment system for anticoagulant rodenticide exposure of raptors
Whole Wildlife Toxicology Catalog
The Whole Wildlife Toxicology Catalog is a compilation of websites containing toxicological information related to amphibians, reptiles, birds and mammals that may be of value to scientists, risk assessors, regulators and natural resource managers.
Utility and Vulnerability Ranking Programs for Terrestrial Vertebrates
To assist decision makers in risk assessments, two sets of indices have been developed to rank terrestrial vertebrates for their utility in biomonitoring and susceptibility.
Contaminant Exposure and Effects-Terrestrial Vertebrates database (CEE-TV)
The Contaminant Exposure and Effects-Terrestrial Vertebrates database (CEE-TV) contains contaminant exposure and effects information for terrestrial vertebrates (birds, mammals, amphibians and reptiles) that reside in estuarine and coastal habitats along the Atlantic, Gulf and Pacific Coasts including Alaska and Hawaii and in the Great Lakes Region.
CEETV FAQs
Frequently Asked Questions for the Contaminant Exposure and Effects-Terrestrial Vertebrates (CEE-TV) Database
Science and Products
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Filter Total Items: 16
Review of Wildlife Health Outcomes and Potentially Toxic Algal Blooms in the Chesapeake Bay
Scientists provide resources that review algal toxin data, explore links between avian mortality and toxin exposure, and identify future research needs to predict algal toxin health hazards and risks for birds and other wildlife in the Chesapeake Bay.Scientists Provide an Understanding of Anticoagulant Rodenticide Exposure in Non-Target Bird Species
U.S. Geological Survey scientists and their partners utilize laboratory and field studies and existing information to improve understanding of anticoagulant rodenticide exposure and effects to wild birds.Hazard and Risk of Anticoagulant Rodenticides to Predatory and Scavenging Wildlife
Invasive mammalian predators are the most damaging group of animals affecting global biodiversity. When introduced on remote islands, alien rodent species can devastate local biota and have been linked to approximately 30% of all extinctions. In addition, rodents can also consume and spoil crops, and serve as disease vectors that affect humans. Starting in the 20th century, rodenticides were...Do pesticide coatings on agricultural seeds pose a threat to earthworms and to the birds that eat them?
Earthworms are a vital part of a healthy, functioning soil ecosystem and are also an important protein-rich food source for wildlife, including many species of birds and mammals. In an agricultural setting, the presence of earthworms can increase crop yields by 25%, but can also expose earthworms to pesticides. Seed treatment is the principal application method for neonicotinoid insecticides, one...Whole Wildlife Toxicology Catalog
Developed in 2008, the Whole Wildlife Toxicology Catalog is a portal to wildlife toxicology-oriented websites and databases. The catalog attempts to compile and provide access to website containing information that should be of value to scientists, regulators, natural resource managers, students and other members of the public. The catalog is updated annually. Please contact Barnett Rattner if you...No Evidence of Toxicity to Birds Ingesting Neonicotinoid-Coated Wheat Seeds During Controlled Laboratory Study
Scientists determined what happens to the neonicotinoid insecticide, imidacloprid, on coated wheat seeds once ingested by Japanese quail (Coturnix japonica)—a model species for free-range, seed-eating, upland game birds. Imidacloprid was found to be rapidly adsorbed, metabolized, and excreted, and resulted in no overt signs of toxicity during a controlled laboratory study.Contaminant-related Activities in Support of Client Agencies in the Department of the Interior
We undertake many research activities in support of the mission of the Department of the Interior. One such activity is to evaluate the potential hazard and risk of environmental contaminants to natural resources.Contaminant Exposure, Food Web Transfer and Potential Health Effects on Chesapeake Bay and Delaware Bay Waterbirds
Chesapeake and Delaware Bays are the largest estuaries on the east coast of the United States. They support extensive fisheries and provide critical habitat for many species of wildlife. These Bays are surrounded by vast agricultural andindustrialized regions, with urbanized areas, all of which are a source of pollution that can affect natural resources. We have long monitored contaminants in this...Long-term Studies Examine Contaminant Exposure and Reproduction of Ospreys Nesting in Two Large United States Estuaries
In a series of studies from 2010 to 2018, U.S. Geological Survey (USGS) scientists detected low levels of legacy contaminants and pharmaceuticals in osprey (Pandion haliaetus) and their food chain within the Chesapeake and Delaware River estuaries. Osprey reproductive success increased during the same period and was determined to be adequate to sustain a stable population in both estuaries.Genomic and Behavioral Effects of the Neonicotinoid Imidacloprid in Birds Exposed Through Pesticide-Coated Seeds
The Challenge: Neonicotinoid pesticides act as agonists of nicotinic acetylcholine receptors (nAChRs) and are designed to be lethal to insects while theoretically posing little to no threat to vertebrates. The perceived safety of neonicotinoids has led to a sharp increase in their use in the United States and globally, since they were first introduced in 1994. The use of the neonicotinoid...Assessing Contaminant Hazards Without a Critter—Advancements in Alternatives to Animal Toxicity Testing
During the past two decades, great strides have been made toward the development and use of ecotoxicity testing methods that reduce animal use or replace animals altogether with in vitro tests or in silico models.Do Neonicotinoid Pesticide Seed Coatings Pose a Hazard to Seed-eating Birds?
Treating or “dressing” of seeds with pesticides is a commonly used method to enhance crop yield in agriculture. Regrettably, such treated seeds can be ingested by wildlife, and depending on the extent of exposure, can cause adverse effects. - Data
Breeding songbird tissue analysis and metal concentrations in tissues, soil and invertebrates collected near nesting sites within the Southeast Missouri Lead Mining District, 2016-19
This dataset provides results for the following: (1) metals concentrations in soils surrounding breeding song bird nest sites; (2) metals concentrations in invertebrates (earthworm and grub composites) collected near nest sites; (3) metals concentrations and delta-aminolevulinic acid dehydratase (ALAD) activity in avian blood samples; and (4) metals concentrations, indicators of oxidative stress aThe Contaminant Exposure and Effects-Terrestrial Vertebrates database (CEE-TV)
The information provided in the Contaminant Exposure and Effects-Terrestrial Vertebrates (CEE-TV) Database profiles available geo-referenced information on contaminant exposure and effects in terrestrial vertebrates along the U. S. Atlantic, Gulf, and Pacific coasts (including Hawaii and Alaska) and the Great Lakes.Toxicological responses to sublethal anticoagulant rodenticide exposure in free-flying red-tailed hawks
An important component of assessing the hazards of anticoagulant rodenticides to non-target wildlife are observations in exposed free-ranging individuals. The objective of this study was to determine if environmentally realistic, sublethal first-generation anticoagulant rodenticide exposures via prey, can result in direct or indirect adverse effects to free-flying raptors. We offered black-tailedAssessing Exposure, Physiological Effects, and Geographic Scope of Anticoagulant Rodenticides in the Critically Endangered California Condor
-Test subject identification information (sample collection site and date, test subject identification number, and sample number) -Clotting time parameters and comments (prothrombin time, Russell’s viper venom time, fibrinogen concentration, and coefficient of variation for replicate analyses)Great Blue Heron collection at Poplar Island Complex and Chesapeake Marshlands National Wildlife Refuge Complex
In the fall of 2005, dead and dying great blue herons (Ardea herodias) exhibiting emaciation, lethargy, inability to fly and a hard abdomen (steatitis confirmed at necropsy) were observed at Poplar Island and nearby Coaches Island (Rattner et al. 2006). Birds were hand captured at or near impoundments (cells) and ponds that contained large algal blooms, and because of poor prognosis were euthanizeToxicokinetics of imidacloprid-coated wheat seeds in Japanese quail (Coturnix coturnix) and an assessment of risk
- Observations of test subjects, - Body weight, organ/tissue weights - Biomarker data (oxidative DNA damage, thyroid hormones, corticosterone, gene expression) in various tissues - Residues as percent of administered dose - Tissues to plasma rations - Metabolites and ratios - Elimination half-livesUse of blood clotting assays to assess anticoagulant rodenticide exposure and effects in free-ranging birds of prey
Observations and treatment of various species of raptorial birds admitted to a rehabilitation facility, and of nestling barn owls observed and sampled in the fieldExamination of contaminant exposure and reproduction of ospreys (Pandion haliaetus) nesting in Delaware Bay and River in 2015
Reproductive Data for All Nests Monitored; Data for Mayfield Analysis; Eggshell thickness, nestling morphological measurements, nestling plasma stable isotopes, and nestling red blood cell oxidative DNA damage; Egg organochlorine pesticide, total PCB, flame retardants, and PCB toxic equivalent concentrations; Fish capture by osprey; Fish pools and size for contaminant analysis; Fish organochlorineInvestigation of pharmaceuticals in water, fish, and ospreys nesting in Delaware River and Bay
Exposure of wildlife to Active Pharmaceutical Ingredients (APIs) is likely to occur but evidence of hazard and risk is limited. One exposure pathway that has received attention is trophic transfer of APIs in a water-fish-osprey food chain. Samples of water, fish plasma and osprey plasma were collected from Delaware River and Bay, and analyzed for 21 APIs. Only 2 of 21 analytes exceeded Method Dete - Multimedia
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Effects of lead exposure on birds breeding in the Southeast Missouri Lead Mining District
Lead mining in the Southeast Missouri Lead Mining District began in the 1700s and continued for nearly 300 years; the waste piles associated with smelting, mining, and milling of lead ores have released metal residues that have contaminated soil and water in the region. Previous studies in the district have indicated potential harm to wildlife, including birds, because of elevated lead concentratiAuthorsRebecka Brasso, Danielle M. Cleveland, Frank R. Thompson, David E. Mosby, Kathy Hixson, Melissa Roach, Barnett A. Rattner, Natalie K. Karouna-Renier, Julia S. LanktonWildlife ecological risk assessment in the 21st century: Promising technologies to assess toxicological effects
Despite advances in toxicity testing and development of new approach methodologies (NAMs) for hazard assessment, the ecological risk assessment (ERA) framework for terrestrial wildlife (i.e., air-breathing amphibians, reptiles, birds, and mammals) has remained unchanged for decades. While survival, growth, and reproductive endpoints derived from whole animal toxicity tests are central to hazard asAuthorsBarnett A. Rattner, Thomas G. Bean, Val R. Beasley, Philippe Berny, Karen M. Eisenreich, John E. Elliott, Margaret L. Eng, Phyllis C. Fuchsman, Mason D. King, Rafael Mateo Soria, Carolyn B. Meyer, Jason M. O’Brien, Christopher J. SaliceToxicological effects assessment for wildlife in the 21st Century: Review of current methods and recommendations for a path forward
Model species (e.g., granivorous gamebirds, waterfowl, passerines, domesticated rodents) have been used for decades in guideline laboratory tests to generate survival, growth and reproductive data for prospective Ecological Risk Assessments (ERAs) for birds and mammals, while officially adopted risk assessment schemes for amphibians and reptiles do not exist. There are recognized shortcomings of cAuthorsThomas G. Bean, Val R. Beasley, Philippe Berny, Karen M. Eisenreich, John E. Elliott, Margaret L. Eng, Phyllis C. Fuchsman, Mark S. Johnson, Mason D. King, Rafael Mateo Soria, Carolyn B. Meyer, Christopher J. Salice, Barnett A. RattnerPreliminary evidence of anticoagulant rodenticide exposure in American kestrels (Falco sparverius) in the western United States
Although there is extensive evidence of declines in the American Kestrel (Falco sparverius) population across North America, the cause of such declines remains a mystery. One hypothesized driver of decline is anticoagulant rodenticide (AR) exposure, which could potentially cause mortality or reduced fitness. We investigated AR exposure in wild American Kestrels in Utah, USA. We collected and testeAuthorsEvan R. Buechley, Dave Oleyar, Jesse Watson, Jennifer Bridgeman, Steven Volker, David A. Goldade, Catherine E. Swift, Barnett A. RattnerDo pharmaceuticals in the environment pose a risk to wildlife?
The vast majority of knowledge related to the question of, “To what extent do pharmaceuticals in the environment pose a risk to wildlife?”, stems from the Asian vulture crisis (>99% decline of some species of old-world vultures on the Indian subcontinent related to the veterinary use of the non-steroidal anti-inflammatory drug (NSAID) diclofenac). The hazard of diclofenac and other NSAIDs (carprofAuthorsThomas G. Bean, Elizabeth A. Chadwick, Marta Herrero-Villar, Rafael Mateo, Vinny Naidoo, Barnett A. RattnerDrivers of Pb, Sb and As release from spent gunshot in wetlands: Enhancement by organic matter and native microorganisms
In many countries the use of lead-based ammunition is prevalent, and results in exposure and poisoning of waterfowl and other species of birds. In waterfowl hunting areas large quantities of spent shot may be deposited in wetland and terrestrial habitats. These pellets can undergo transformation, which are influenced by various abiotic and biotic factors. In addition to lead (Pb), other elements lAuthorsAnna Potysz, Łukasz J. Binkowski, Jakub Kierczak, Barnett A. RattnerCollateral damage: Anticoagulant rodenticides pose threats to California condors
Anticoagulant rodenticides (ARs) are widespread environmental contaminants that pose risks to scavenging birds because they routinely occur within their prey and can cause secondary poisoning. However, little is known about AR exposure in one of the rarest avian scavengers in the world, the California condor (Gymnogyps californianus). We assessed AR exposure in California condors and surrogate turAuthorsGarth Herring, Collin Eagles-Smith, Rachel Wolstenholme, Alacia Welch, Chris West, Barnett A. RattnerToxicological responses to sublethal anticoagulant rodenticide exposure in free-flying hawks
An important component of assessing the hazards of anticoagulant rodenticides to non-target wildlife is observations in exposed free-ranging individuals. The objective of this study was to determine whether environmentally realistic, sublethal first-generation anticoagulant rodenticide (FGAR) exposures via prey can result in direct or indirect adverse effects to free-flying raptors. We offered blaAuthorsNimish B. Vyas, Barnett A. Rattner, J. Michael Lockhart, Craig S. Hulse, Clifford P. Rice, Frank Kuncir, Kevin KritzA critical review of bioaccumulation and biotransformation of organic chemicals in birds
A literature review of bioaccumulation and biotransformation of organic chemicals in birds was undertaken, aiming to support scoping and prioritization of future research. The objectives were to characterize available bioaccumulation/biotransformation data, identify knowledge gaps, determine how extant data can be used, and explore the strategy and steps forward. An intermediate approach balancedAuthorsDave T. F. Kuo, Barnett A. Rattner, Sarah C. Marteinson, Robert J. Letcher, Kim J. Fernie, Gabriele Treu, Markus Deutsch, Mark S. Johnson, Sandrine Deglin, Michelle EmbryExposure of predatory and scavenging birds to anticoagulant rodenticides in France: Exploration of data from French surveillance programs
Wild raptors are widely used to assess exposure to different environmental contaminants, including anticoagulant rodenticides (ARs). ARs are used on a global scale for rodent control, and act by disruption of the vitamin K cycle that results in haemorrhage usually accompanied by death within days. Some ARs are highly persistent and bioaccumulative, which can cause significant exposure of non-targeAuthorsMeg-Anne Moriceau, Sébastien Lefebvre, Isabelle Fourel, Etienne Benoit, Florence Buronfosse, Pascal Orabi, Barnett A. Rattner, Virginie LattardMeasuring U.S. Federal Agency progress toward implementation of alternative methods in toxicity testing
The U.S. Government Accountability Office (GAO) recommended to Congress that federal agencies establish a workgroup through ICCVAM to propose metrics for assessing progress on the development and promotion of alternative methods. This document describes the recommendations of the ICCVAM Metrics Workgroup.AuthorsJohn D. Gordon, Carol Clarke, Matthew Johnson, Emily N. Reinke, Barnett A. Rattner, Steve Hwang, Evisabel Craig, Anna Lowit, Paul Brown, Karen L. Davis-Bruno, Annabelle Crusan, Suzanne Fitzpatrick, Jueichuan Kang, Robin Levis, Donna L. Mendrick, Jill Merrill, Brian Berridge, Warren Casey, Nicole Kleinstreuer, Harold WatsonEvaluating a rapid field assessment system for anticoagulant rodenticide exposure of raptors
Anticoagulant rodenticides (ARs) are commonly used to control rodent pests. However, worldwide, their use is associated with secondary and tertiary poisoning of nontarget species, especially predatory and scavenging birds. No medical device can rapidly test for AR exposure of avian wildlife. Prothrombin time (PT) is a useful biomarker for AR exposure, and multiple commercially available point-of-cAuthorsAriana J Dickson, James R. Belthoff, Kristen A Mitchell, Brian W. Smith, Zachary P. Wallace, Matthew J. Stuber, Michael J. Lockhart, Barnett A. Rattner, Todd E. Katzner - Web Tools
Whole Wildlife Toxicology Catalog
The Whole Wildlife Toxicology Catalog is a compilation of websites containing toxicological information related to amphibians, reptiles, birds and mammals that may be of value to scientists, risk assessors, regulators and natural resource managers.
- Software
Utility and Vulnerability Ranking Programs for Terrestrial Vertebrates
To assist decision makers in risk assessments, two sets of indices have been developed to rank terrestrial vertebrates for their utility in biomonitoring and susceptibility.
Contaminant Exposure and Effects-Terrestrial Vertebrates database (CEE-TV)
The Contaminant Exposure and Effects-Terrestrial Vertebrates database (CEE-TV) contains contaminant exposure and effects information for terrestrial vertebrates (birds, mammals, amphibians and reptiles) that reside in estuarine and coastal habitats along the Atlantic, Gulf and Pacific Coasts including Alaska and Hawaii and in the Great Lakes Region.
CEETV FAQs
Frequently Asked Questions for the Contaminant Exposure and Effects-Terrestrial Vertebrates (CEE-TV) Database
- News
*Disclaimer: Listing outside positions with professional scientific organizations on this Staff Profile are for informational purposes only and do not constitute an endorsement of those professional scientific organizations or their activities by the USGS, Department of the Interior, or U.S. Government