Dana W Kolpin
Biography
Dana received his B.S. from Iowa State University and his M.S. from the University of Iowa (both in geology). Dana started his career with the USGS in 1986. His research interests include the fate, transport, and effects of environmental contaminants (e.g. pesticides, human and veterinary pharmaceuticals, hormones, etc.) in the environment. He was the project lead of the USGS Toxic Program’s CECs in the Environment Project (https://toxics.usgs.gov/investigations/cec/) for its entire history (1998 – 2017). He now project lead of the USGS Toxic Program’s newly formed Food Project (i.e. understanding the potential for health risks from contaminant exposures associated with production, manufacturing, use, and consumption of food, beverage, and feedstock products: https://www2.usgs.gov/envirohealth/science_teams/food/index.php). He has published over 200 papers and reports on environmental contaminants. His paper "Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: A national reconnaissance" was a seminal paper on the occurrence of CECs in water resources, and was the first national-scale study of such compounds conducted in the United States. This paper has become the most heavily cited paper in Environmental Science & Technology history. He has published a diverse array of papers on the topic of environmental contaminants including research on CECs in landfills, changes in stream water chemistry and hydrology related to the closure of a wastewater treatment plant, detection of swine hepatitis E virus in streams, the transport of neonicotinoid insecticides in streams, the uptake of CECs into earthworms and into fish neural tissue, the occurrence of natural toxins (i.e. phytoestrogens and mycotoxins) in streams, and the first ever documentation of the off-field transport on nitrapyrin and herbicide safeners to streams. His most recent research interests include linking tap water quality to human health end points, investigating PFAS exposures in rural settings, determining the prevalence of antibiotic resistance genes in the environment, and understanding chemical and microbial contaminants being discharged into the environment by food and feedstock processing plants.
Science and Products
Costs and Benefits of Nitrapyrin
In December 2020, our research group (as part of the Food Integrated Science Team) published a review of nitrapyrin costs and benefits in the journal Environmental Science & Technology.
U.S. Geological Survey Research Scientist Recognized for Advancing Exposure Science
U.S. Geological Survey (USGS) Scientist Dana Kolpin was presented the International Environmental Award by Reciphram celebrating his research on the occurrence, sources, fate, and effects of environmental contaminants such as pharmaceuticals and pesticides.
Ongoing Research to Characterize the Complexity of Chemical Mixtures in Water Resources—Urban Stormwater
A multiagency reconnaissance study of chemicals in urban stormwater, sampled from pipes or ditches during 50 runoff events at 21 sites in 17 states across the United States, demonstrated that stormwater runoff contains complex mixtures of chemicals including polycyclic aromatic hydrocarbons, pesticides, and pharmaceuticals that are indicative of multiple sources in the watershed.
Per- and Polyfluoroalkyl Substances (PFASs) detected in Source Waters and Treated Public Water Supplies
This study, which measured 17 per- and polyfuoroalkyl substances (PFASs) in source and treated public water supplies from 25 drinking water facilities as part of a broader study of contaminants in drinking water across the United States, reports that PFASs were detected in all source water and public water supply samples collected. One sample exceeded the current U.S. Environmental...
Novel Approach Improves Understanding of Virus Occurrence in Drinking Water
Waterborne viruses, one of the leading causes of gastrointestinal illnesses, were measured in United States drinking water sources and finished water. Scientists used a combination of measurement and statistical techniques to overcome limitations to quantifying these viruses, thus offering an enhanced method for virus monitoring.
Food Resources Science Team
The team studies the movement of toxicants and pathogens associated with food production through watersheds and aquifers, to water resources where exposure can occur. That information is used to understand if there are adverse effects upon exposure and to develop decision tools to protect health.
Exploring the Suitability of a Modeling Approach to Estimate Contaminant Occurrence in Drinking Water Sources
Scientists explored the suitability of the DeFacto Reuse in our Nation's Consumable Supply (DRINCS) model to estimate the likelihood of contaminants from upstream wastewater discharges to enter drinking water facility intakes.
Selected Pharmaceuticals Not Likely to Persist in Wild Fish: Results of Uptake and Elimination Testing
Laboratory study shows that both uptake and elimination of selected pharmaceuticals within bluegill tissues is rapid indicating that persistence in bluegills in the environment is likely to be low except in those fish that reside downstream from a consistent, substantial, contaminant source.
Comparison of Predicted and Measured Pharmaceutical Concentrations in Rivers
New study evaluated if predicted environmental concentrations (PECs) of pharmaceuticals (based on pharmaceutical usage data, degree of metabolism in humans, removal in wastewater treatment plants (WWTPs), and environmental dilution), reflect actual measured environmental concentrations (MECs) in two rivers of different sizes and demographics.
Occurrence of Avian Influenza Virus in Groundwater—Study Provides Baseline Data and Informs Future Studies
This pilot study provided baseline data on avian influenza virus (AIV) occurrence in groundwater underlying poultry farms and documented the challenges for conducting a pathogen transport study during a disease outbreak.
Multi-State Survey Measures Parabens in Municipal Wastewater Biosolids
This study provides new information about the composition and concentrations of 5 parabens—preservatives in pharmaceuticals and personal care products—present in biosolids collected from 14 municipal wastewater treatment plants across the United States.
Understanding Chemical and Microbial Contaminants in Public Drinking Water
Collaborative joint agency study provides nationally consistent and rigorously quality-assured datasets on a wide range of chemical and microbial contaminants present in source and treated public drinking water supplies. Tap water was not analyzed in this study.
Environmental and anthropogenic drivers of contaminants in agricultural watersheds with implications for land management
If not managed properly, modern agricultural practices can alter surface and groundwater quality and drinking water resources resulting in potential negative effects on aquatic and terrestrial ecosystems. Exposure to agriculturally derived contaminant mixtures has the potential to alter habitat quality and negatively affect fish and other aquatic...
Smalling, Kelly; Devereux, Olivia H.; Gordon, Stephanie; Phillips, Patrick J.; Blazer, Vicki S.; Hladik, Michelle; Kolpin, Dana W.; Meyer, Michael T.; Sperry, Adam; Wagner, Tyler In vitro effects-based method and water quality screening model for use in pre- and post-distribution treated waters
Recent urban public water supply contamination events emphasize the importance of screening treated drinking water quality after distribution. In vitro bioassays, when run concurrently with analytical chemistry methods, are effective tools to evaluating the efficacy of water treatment processes and water quality. We tested 49 water...
Medlock-Kakaley, Elizabeth; Cardon, Mary C.; Evans, Nicola; Iwanowicz, Luke R.; Allen, Joshua M.; Wagner, Elizabeth; Bokenkamp, Katherine; Richardson, Susan D; Plewa, Michael J; Bradley, Paul; Romanok, Kristin; Kolpin, Dana W.; Conley, Justin M.; Gray, L. Earl Jr.; Hartig, Phillip C.; Wilson, Vickie S. Widespread use of the nitrification inhibitor nitrapyrin: Assessing benefits and costs to agriculture, ecosystems, and environmental health
Agricultural production and associated applications of nitrogen (N) fertilizers have increased dramatically in the last century, and current projections to 2050 show that demands will continue to increase as the human population grows. Applied in both organic and inorganic fertilizer forms, N is an essential nutrient in crop productivity....
Woodward, Emily; Edwards, Thea Margaret; Givens, Carrie E; Kolpin, Dana W.; Hladik, Michelle Occurrence and spatiotemporal dynamics of pharmaceuticals in a temperate-region wastewater effluent-dominated stream: Variable inputs and differential attenuation yield evolving complex exposure mixtures
Effluent-dominated streams are becoming increasingly common in temperate regions and generate complex pharmaceutical mixture exposure conditions that may impact aquatic organisms via drug–drug interactions. Here, we quantified spatiotemporal pharmaceutical exposure concentrations and composition mixture dynamics during baseflow conditions at four...
Zhi, Hui; Kolpin, Dana W.; Klaper, R.D.; Iwanowicz, Luke R.; Meppelink, Shannon M.; LeFevre, Gregory H. Poultry litter as potential source of pathogens and other contaminants in groundwater and surface water proximal to large-scale confined poultry feeding operations
Manure from livestock production has been associated with the contamination of water resources. To date, research has primarily focused on runoff of these contaminants from animal operations into surface water, and the introduction of poultry-derived pathogenic zoonoses and other contaminants into groundwater is under-investigated. We...
Hubbard, Laura E.; Givens, Carrie E.; Griffin, Dale W.; Iwanowicz, Luke; Meyer, Michael T.; Kolpin, Dana W. Polymeric nanofiber-carbon nanotube composite mats as fast-equilibrium passive samplers for polar organic pollutants
To improve the performance of polymeric electrospun nanofiber mats (ENMs) for equilibrium passive sampling applications in water, we integrated two types of multiwalled carbon nanotubes (CNTs; with and without surface carboxyl groups) into polyacrylonitrile (PAN) and polystyrene (PS) ENMs. For 11 polar and moderately hydrophobic compounds (−0.07...
Qian, Jiajie; Martinez, Andres; Marek, Rachel F; Nagorzanski, Matthew R.; Zhi, Hui; Furlong, Edward; Kolpin, Dana W.; LeFevre, Gregory H.; Cwiertny, David M. A critical review on the potential impacts of neonicotinoid insecticide use: Current knowledge of environmental fate, toxicity, and implications for human health
Neonicotinoid insecticides are widely used in both urban and agricultural settings around the world. Historically, neonicotinoid insecticides have been viewed as ideal replacements for more toxic compounds, like organophosphates, due in part to their perceived limited potential to affect the environment and human health. This critical review...
Lehmler, Hans-Joachim; Kolpin, Dana W.; Hladik, Michelle; Vargo, John D.; Schilling, Keith E.; LeFevre, Gregory H.; Peeples, Tonya L.; Poch, Matthew C.; LaDuca, Lauren E.; Cwiertny, David M.; Field, R. William Landfill leachate contributes per-/poly-fluoroalkyl substances (PFAS) and pharmaceuticals to municipal wastewater
Widespread disposal of landfill leachate to municipal sewer infrastructure in the United States calls for an improved understanding of the relative organic-chemical contributions to the wastewater treatment plant (WWTP) waste stream and associated surface-water discharge to receptors in the environment. Landfill leachate, WWTP influent, and WWTP...
Masoner, Jason R.; Kolpin, Dana W.; Cozzarelli, Isabelle M.; Smalling, Kelly L.; Bolyard, Stephanie; Field, Jennifer; Furlong, Edward T.; Gray, James L.; Lozinski, Duncan; Reinhart, Debra; Rodowa, Alix; Bradley, Paul M. Mixed organic and inorganic tapwater exposures and potential effects in greater Chicago area, USA
Safe drinking water at the point of use (tapwater, TW) is a public-health priority. TW exposures and potential human-health concerns of 540 organics and 35 inorganics were assessed in 45 Chicago area United States (US) homes in 2017. No US Environmental Protection Agency (EPA) enforceable Maximum Contaminant Level(s) (MCL) were exceeded in any...
Bradley, Paul; Argos, Maria; Kolpin, Dana W.; Meppelink, Shannon M.; Romanok, Kristin; Smalling, Kelly; Focazio, Michael J.; Allen, Joshua M.; Dietze, Julie E.; Devito, Michael J.; Donovan, Ariel; Evans, Nicola; Givens, Carrie E.; Gray, James L.; Higgins, Christopher P.; Hladik, Michelle; Iwanowicz, Luke; Journey, Celeste A.; Lane, Rachael; Laughrey, Zachary; Loftin, Keith A.; McCleskey, R. Blaine; McDonough, Carrie A.; Medlock Kakaley, Elizabeth K; Meyer, Michael T.; Holthouse-Putz, Andrea; Richardson, Susan D; Stark, Alan ; Weis, Christopher P.; Wilson, Vickie S.; Zehraoui, Abderrahman De facto water reuse: Bioassay suite approach delivers depth and breadth in endocrine active compound detection
Although endocrine disrupting compounds (EDCs) have been detected in wastewater and surface waters worldwide using a variety of in vitro effects-based screening tools, e.g. bioassays, few have examined potential attenuation of environmental contaminants by both natural (sorption, degradation, etc) and anthropogenic (water treatment practices)...
Medlock Kakaley, Elizabeth K; Blackwell, Brett R.; Cardon, Mary C.; Conley, Justin M.; Evans, Nicola; Feifarek, David J.; Furlong, Edward; Glassmeyer, Susan T.; Gray, L. Earl Jr.; Hartig, Phillip C.; Kolpin, Dana W.; Mills, Marc A.; Rosenblum, Laura; Villeneuve, Daniel L.; Wilson, Vickie S. Urban stormwater: An overlooked pathway of extensive mixed contaminants to surface and groundwaters in the United States
Increasing global reliance on stormwater control measures to reduce discharge to surface water, increase groundwater recharge, and minimize contaminant delivery to receiving waterbodies necessitates improved understanding of stormwater-contaminant profiles. A multi-agency study of organic and inorganic chemicals in urban stormwater from 50 runoff...
Masoner, Jason R.; Kolpin, Dana W.; Cozzarelli, Isabelle M.; Barber, Larry B.; Burden, D.S.; Foreman, William T.; Forshay, Kenneth J.; Furlong, Edward; Groves, Justin F.; Hladik, Michelle; Hopton, Matthew E.; Jaeschke, Jeanne B.; Keefe, Steffanie H.; Krabbenhoft, David; Lowrance , Richard; Romanok, Kristin; Rus, David L.; Selbig, William R.; Williams, Brad; Bradley, Paul Predictive analysis using chemical-gene interaction networks consistent with observed endocrine activity and mutagenicity of U.S. streams
In a recent U.S. Geological Survey/U.S. Environmental Protection Agency study assessing >700 organic compounds in 38 streams, in vitro assays indicated generally low estrogen, androgen, and glucocorticoid receptor activities, but identified 13 surface waters with 17β estradiol equivalent (E2Eq) activities greater than the 1 ng/L level of...
Berninger, Jason P.; DeMarini, David M.; Warren, Sarah H.; Simmons, Jane Ellen; Wilson, Vickie S.; Conley, Justin M.; Armstrong, Mikayla D.; Kolpin, Dana W.; Kuivila, Kathryn; Reilly, Timothy J.; Romanok, Kristin M.; Villeneuve, Daniel L.; Bradley, Paul M.; Iwanowicz, Luke R.
Understanding how Pharmaceuticals in the Environment Affect Fish
Fish health may be affected by pharmaceuticals in treated wastewater released into streams and other water bodies, according to a recent laboratory and field study by the Aquatic Toxicology Laboratory at St. Cloud State University and the U.S. Geological Survey (USGS).
Storage and Treatment of Liquid Waste from Landfills Doesn’t Remove All Contaminants, Including Pharmaceuticals
New research from the U.S. Geological Survey details that even after the storage and/or treatment of leachate – liquid waste that moves through or drains from a landfill − it can still contain a multitude of chemicals and reflects the diverse nature of residential, industrial, and commercial waste discarded into landfills in the United States.