On-site mobile laboratory located near groundwater monitoring wells on Cape Cod, Massachusetts
Larry B Barber, II
Dr. Larry Barber is a Research Geologist with the USGS Water Resources Mission Area and Integrated Water Chemistry Assessment Laboratory.
I joined the USGS NRP as a student appointments in 1982. Since then, my research has involved long-term interdisciplinary research projects that characterize environmental sources of organic and inorganic contaminants, quantify the biogeochemical processes that control their fate, and assess their potential effects on aquatic ecosystems and human health. Particular emphasis is focused on the interactions between chemistry, hydrology, and biology. A major area of expertise is the analysis of emerging contaminants by gas chromatography/tandem mass spectrometry, which provides a foundation for assessing their occurrence, exposure pathways, and impacts.
Current research focuses on biologically-active contaminants and receiving water (surface water and groundwater) attenuation capacity. Compounds being investigated include endocrine disrupting chemicals, neuro-active pharmaceuticals, and antimicrobials. We develop state-of-the-science approaches to landscape-based, watershed-scale (second-order streams to continental rivers) evaluation of chemical loading and fate combined with the field-based biological assays, to establish a holistic understanding of contaminant behavior and impacts. This interdisciplinary research involves teams of scientists to allow comprehensive evaluation of critical water resource issues.
Education and Certifications
Ph.D., University of Colorado, Department of Geological Science, Boulder, CO, 1990
M.Sc., University of Colorado, Department of Geological Science, Boulder, CO, 1985
B.Sc., University of Arkansas, Department of Geology, Fayetteville, AR, 1980
Science and Products
Not All PFAS Are Alike: Fish Responses Reveal The Importance Of Real-World Mixtures
A Decade of Data Reveals Imidacloprid (a common insecticide) is Increasing in American Rivers
Applying Multiple Tools to Inform Management of Per- and Polyfluoroalkyl Substances (PFAS) in the Potomac River Watershed
Navigating PFAS Contamination: Insights from the USGS Potomac River Watershed Study
Human-Related Compounds in Water Sources in the Grand Canyon Help Identify Water Flow Pathways and Highlight Potential Water Quality Changes
Unique Approach to Measure Per- and Polyfluoroalkyl Substances Uptake in Fish, Mussels, and Passive Samplers
Integrated Assessments of Potential Risks to Aquatic Organisms and Public Water Supply from Wastewater-Derived Chemical Mixtures in the Chesapeake Bay Watershed
Refined Model Provides a Screening Tool to Understand Exposure to Contaminants from Incidental Wastewater Reuse
GIS-based landscape analysis to identify sources of endocrine disrupting chemicals
Per- and Polyfluoroalkyl Substances From Firefighting and Domestic Wastewater Remain in Groundwater for Decades
Long-Term Study Finds Endocrine Disrupting Chemicals in Urban Waterways
Neuroactive Pharmaceuticals in Minnesota Rivers
Assessment of sperm motility, apoptosis, and viability of Fathead Minnows (Pimephales promelas) exposed to polyfluorinated alkyl substances (PFAS) at Cape Cod, MA in 2024 Assessment of sperm motility, apoptosis, and viability of Fathead Minnows (Pimephales promelas) exposed to polyfluorinated alkyl substances (PFAS) at Cape Cod, MA in 2024
Low pH Exposure Alters Mediator Dependent Response in Poly(o-phenylenediamine) Based Molecularly Imprinted Polymer – Electrochemical Sensors (MIP-ES) Low pH Exposure Alters Mediator Dependent Response in Poly(o-phenylenediamine) Based Molecularly Imprinted Polymer – Electrochemical Sensors (MIP-ES)
Water-quality results for municipal effluents, surface water, and urban stormwater: Use of constructed wetlands to support indirect potable reuse in Lake Thunderbird, Oklahoma, 2022-2024 Water-quality results for municipal effluents, surface water, and urban stormwater: Use of constructed wetlands to support indirect potable reuse in Lake Thunderbird, Oklahoma, 2022-2024
Per- and polyfluoroalkyl substances (PFAS), major elements, and trace elements in surface waters of the Upper Colorado River Basin, May 2022 to June 2024 Per- and polyfluoroalkyl substances (PFAS), major elements, and trace elements in surface waters of the Upper Colorado River Basin, May 2022 to June 2024
Laboratory-based optical measurements for surface waters of the Upper Colorado River Basin collected during synoptic raft trips Laboratory-based optical measurements for surface waters of the Upper Colorado River Basin collected during synoptic raft trips
Water quality and contaminants in stream surface waters collected in the Delmarva Peninsula, 2022 (ver. 1.1, June 2026) Water quality and contaminants in stream surface waters collected in the Delmarva Peninsula, 2022 (ver. 1.1, June 2026)
Assessment of sperm quality parameters from fathead minnows exposed to polyfluorinated alkyl substances (PFAS) at Cape Cod, MA in 2019 Assessment of sperm quality parameters from fathead minnows exposed to polyfluorinated alkyl substances (PFAS) at Cape Cod, MA in 2019
Assessment sperm quality parameters from fathead minnows exposed to polyfluorinated alkyl substances (PFAS) at Cape Cod, MA in 2021 Assessment sperm quality parameters from fathead minnows exposed to polyfluorinated alkyl substances (PFAS) at Cape Cod, MA in 2021
Laboratory-based optical measurements for water samples collected from fixed monitoring stations within the Upper Colorado River and Illinois River basins Laboratory-based optical measurements for water samples collected from fixed monitoring stations within the Upper Colorado River and Illinois River basins
Reproductive biomarker responses in male fathead minnow exposed to per- and polyfluoroalkyl substances contaminated groundwater at a fire-training area, Cape Cod, Massachusetts from 2019 and 2021 Reproductive biomarker responses in male fathead minnow exposed to per- and polyfluoroalkyl substances contaminated groundwater at a fire-training area, Cape Cod, Massachusetts from 2019 and 2021
Water quality and contaminants in stream surface waters collected in Southeast Pennsylvania and Maryland Piedmont mixed agriculture, 2023 (ver. 1.1, June 2026) Water quality and contaminants in stream surface waters collected in Southeast Pennsylvania and Maryland Piedmont mixed agriculture, 2023 (ver. 1.1, June 2026)
Per- and Polyfluoroalkyl Substances (PFAS) and Co-occurring Contaminants in the Fraser River, a Headwater Tributary to the Colorado River - September 2021 to August 2023 Per- and Polyfluoroalkyl Substances (PFAS) and Co-occurring Contaminants in the Fraser River, a Headwater Tributary to the Colorado River - September 2021 to August 2023
On-site mobile laboratory located near groundwater monitoring wells on Cape Cod, Massachusetts
On-site mobile laboratories located near groundwater monitoring wells on Cape Cod, Massachusetts
On-site mobile laboratories located near groundwater monitoring wells on Cape Cod, Massachusetts
Fathead minnows swimming in an experimental aquarium
Fathead minnows swimming in an experimental aquariumFathead minnows (Pimephales promelas) swimming in an expermental aquaium. The aquarium is part of an experiment to assess endocrine disruption in fish.
Fathead minnows swimming in an experimental aquarium
Fathead minnows swimming in an experimental aquariumFathead minnows (Pimephales promelas) swimming in an expermental aquaium. The aquarium is part of an experiment to assess endocrine disruption in fish.
Fathead minnows swimming in an experimental aquarium
Fathead minnows swimming in an experimental aquariumBioactive Chemicals Research Laboratory — Boulder, Colorado. Fathead minnows (Pimephales promelas) swimming in an experimental aquarium. The aquarium is part of an experiment to assess endocrine disruption in fish.
Fathead minnows swimming in an experimental aquarium
Fathead minnows swimming in an experimental aquariumBioactive Chemicals Research Laboratory — Boulder, Colorado. Fathead minnows (Pimephales promelas) swimming in an experimental aquarium. The aquarium is part of an experiment to assess endocrine disruption in fish.
Surface-water/groundwater boundaries affect seasonal PFAS concentrations and PFAA precursor transformations Surface-water/groundwater boundaries affect seasonal PFAS concentrations and PFAA precursor transformations
Effects of an extreme flood on trace elements in river water—From urban stream to major river basin Effects of an extreme flood on trace elements in river water—From urban stream to major river basin
Determination of steroid hormones and related compounds in filtered and unfiltered water by solid-phase extraction, derivatization, and gas chromatography with tandem mass spectrometry Determination of steroid hormones and related compounds in filtered and unfiltered water by solid-phase extraction, derivatization, and gas chromatography with tandem mass spectrometry
Occurrence of triclosan, triclocarban, and its lesser chlorinated congeners in Minnesota freshwater sediments collected near wastewater treatment plants Occurrence of triclosan, triclocarban, and its lesser chlorinated congeners in Minnesota freshwater sediments collected near wastewater treatment plants
Endocrine disrupting chemicals in Minnesota lakes - Water-quality and hydrological data from 2008 and 2010 Endocrine disrupting chemicals in Minnesota lakes - Water-quality and hydrological data from 2008 and 2010
USGS Environmental health science strategy: providing environmental health science for a changing world: Public review release USGS Environmental health science strategy: providing environmental health science for a changing world: Public review release
Groundwater-quality data for a treated-wastewater plume near the Massachusetts Military Reservation, Ashumet Valley, Cape Cod, Massachusetts, 2006-08 Groundwater-quality data for a treated-wastewater plume near the Massachusetts Military Reservation, Ashumet Valley, Cape Cod, Massachusetts, 2006-08
Concentration of organic contaminants in fish and their biological effects in a wastewater-dominated urban stream Concentration of organic contaminants in fish and their biological effects in a wastewater-dominated urban stream
Effect of dissolved organic carbon on the transport and attachment behaviors of Cryptosporidium parvum oocysts and carboxylate-modified microspheres advected through temperate humic and tropical volcanic agricultural soil Effect of dissolved organic carbon on the transport and attachment behaviors of Cryptosporidium parvum oocysts and carboxylate-modified microspheres advected through temperate humic and tropical volcanic agricultural soil
Lagrangian sampling of wastewater treatment plant effluent in Boulder Creek, Colorado, and Fourmile Creek, Iowa, during the summer of 2003 and spring of 2005— Hydrological and water-quality data Lagrangian sampling of wastewater treatment plant effluent in Boulder Creek, Colorado, and Fourmile Creek, Iowa, during the summer of 2003 and spring of 2005— Hydrological and water-quality data
Biodegradation and attenuation of steroidal hormones and alkylphenols by stream biofilms and sediments Biodegradation and attenuation of steroidal hormones and alkylphenols by stream biofilms and sediments
Endocrine active chemicals, pharmaceuticals, and other chemicals of concern in surface water, wastewater-treatment plant effluent, and bed sediment, and biological characteristics in selected streams, Minnesota: Design, methods, and data, 2009 Endocrine active chemicals, pharmaceuticals, and other chemicals of concern in surface water, wastewater-treatment plant effluent, and bed sediment, and biological characteristics in selected streams, Minnesota: Design, methods, and data, 2009
Interactive Map: GIS-based landscape analysis to identify sources of endocrine disrupting chemicals Interactive Map: GIS-based landscape analysis to identify sources of endocrine disrupting chemicals
Science and Products
Not All PFAS Are Alike: Fish Responses Reveal The Importance Of Real-World Mixtures
A Decade of Data Reveals Imidacloprid (a common insecticide) is Increasing in American Rivers
Applying Multiple Tools to Inform Management of Per- and Polyfluoroalkyl Substances (PFAS) in the Potomac River Watershed
Navigating PFAS Contamination: Insights from the USGS Potomac River Watershed Study
Human-Related Compounds in Water Sources in the Grand Canyon Help Identify Water Flow Pathways and Highlight Potential Water Quality Changes
Unique Approach to Measure Per- and Polyfluoroalkyl Substances Uptake in Fish, Mussels, and Passive Samplers
Integrated Assessments of Potential Risks to Aquatic Organisms and Public Water Supply from Wastewater-Derived Chemical Mixtures in the Chesapeake Bay Watershed
Refined Model Provides a Screening Tool to Understand Exposure to Contaminants from Incidental Wastewater Reuse
GIS-based landscape analysis to identify sources of endocrine disrupting chemicals
Per- and Polyfluoroalkyl Substances From Firefighting and Domestic Wastewater Remain in Groundwater for Decades
Long-Term Study Finds Endocrine Disrupting Chemicals in Urban Waterways
Neuroactive Pharmaceuticals in Minnesota Rivers
Assessment of sperm motility, apoptosis, and viability of Fathead Minnows (Pimephales promelas) exposed to polyfluorinated alkyl substances (PFAS) at Cape Cod, MA in 2024 Assessment of sperm motility, apoptosis, and viability of Fathead Minnows (Pimephales promelas) exposed to polyfluorinated alkyl substances (PFAS) at Cape Cod, MA in 2024
Low pH Exposure Alters Mediator Dependent Response in Poly(o-phenylenediamine) Based Molecularly Imprinted Polymer – Electrochemical Sensors (MIP-ES) Low pH Exposure Alters Mediator Dependent Response in Poly(o-phenylenediamine) Based Molecularly Imprinted Polymer – Electrochemical Sensors (MIP-ES)
Water-quality results for municipal effluents, surface water, and urban stormwater: Use of constructed wetlands to support indirect potable reuse in Lake Thunderbird, Oklahoma, 2022-2024 Water-quality results for municipal effluents, surface water, and urban stormwater: Use of constructed wetlands to support indirect potable reuse in Lake Thunderbird, Oklahoma, 2022-2024
Per- and polyfluoroalkyl substances (PFAS), major elements, and trace elements in surface waters of the Upper Colorado River Basin, May 2022 to June 2024 Per- and polyfluoroalkyl substances (PFAS), major elements, and trace elements in surface waters of the Upper Colorado River Basin, May 2022 to June 2024
Laboratory-based optical measurements for surface waters of the Upper Colorado River Basin collected during synoptic raft trips Laboratory-based optical measurements for surface waters of the Upper Colorado River Basin collected during synoptic raft trips
Water quality and contaminants in stream surface waters collected in the Delmarva Peninsula, 2022 (ver. 1.1, June 2026) Water quality and contaminants in stream surface waters collected in the Delmarva Peninsula, 2022 (ver. 1.1, June 2026)
Assessment of sperm quality parameters from fathead minnows exposed to polyfluorinated alkyl substances (PFAS) at Cape Cod, MA in 2019 Assessment of sperm quality parameters from fathead minnows exposed to polyfluorinated alkyl substances (PFAS) at Cape Cod, MA in 2019
Assessment sperm quality parameters from fathead minnows exposed to polyfluorinated alkyl substances (PFAS) at Cape Cod, MA in 2021 Assessment sperm quality parameters from fathead minnows exposed to polyfluorinated alkyl substances (PFAS) at Cape Cod, MA in 2021
Laboratory-based optical measurements for water samples collected from fixed monitoring stations within the Upper Colorado River and Illinois River basins Laboratory-based optical measurements for water samples collected from fixed monitoring stations within the Upper Colorado River and Illinois River basins
Reproductive biomarker responses in male fathead minnow exposed to per- and polyfluoroalkyl substances contaminated groundwater at a fire-training area, Cape Cod, Massachusetts from 2019 and 2021 Reproductive biomarker responses in male fathead minnow exposed to per- and polyfluoroalkyl substances contaminated groundwater at a fire-training area, Cape Cod, Massachusetts from 2019 and 2021
Water quality and contaminants in stream surface waters collected in Southeast Pennsylvania and Maryland Piedmont mixed agriculture, 2023 (ver. 1.1, June 2026) Water quality and contaminants in stream surface waters collected in Southeast Pennsylvania and Maryland Piedmont mixed agriculture, 2023 (ver. 1.1, June 2026)
Per- and Polyfluoroalkyl Substances (PFAS) and Co-occurring Contaminants in the Fraser River, a Headwater Tributary to the Colorado River - September 2021 to August 2023 Per- and Polyfluoroalkyl Substances (PFAS) and Co-occurring Contaminants in the Fraser River, a Headwater Tributary to the Colorado River - September 2021 to August 2023
On-site mobile laboratory located near groundwater monitoring wells on Cape Cod, Massachusetts
On-site mobile laboratory located near groundwater monitoring wells on Cape Cod, Massachusetts
On-site mobile laboratories located near groundwater monitoring wells on Cape Cod, Massachusetts
On-site mobile laboratories located near groundwater monitoring wells on Cape Cod, Massachusetts
Fathead minnows swimming in an experimental aquarium
Fathead minnows swimming in an experimental aquariumFathead minnows (Pimephales promelas) swimming in an expermental aquaium. The aquarium is part of an experiment to assess endocrine disruption in fish.
Fathead minnows swimming in an experimental aquarium
Fathead minnows swimming in an experimental aquariumFathead minnows (Pimephales promelas) swimming in an expermental aquaium. The aquarium is part of an experiment to assess endocrine disruption in fish.
Fathead minnows swimming in an experimental aquarium
Fathead minnows swimming in an experimental aquariumBioactive Chemicals Research Laboratory — Boulder, Colorado. Fathead minnows (Pimephales promelas) swimming in an experimental aquarium. The aquarium is part of an experiment to assess endocrine disruption in fish.
Fathead minnows swimming in an experimental aquarium
Fathead minnows swimming in an experimental aquariumBioactive Chemicals Research Laboratory — Boulder, Colorado. Fathead minnows (Pimephales promelas) swimming in an experimental aquarium. The aquarium is part of an experiment to assess endocrine disruption in fish.