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Publications

Dive into our publications and explore the science from the Environmental Health Program (Toxic Substances Hydrology and Contaminant Biology).

Filter Total Items: 683

Direct and delayed mortality of Ceriodaphnia dubia and rainbow trout following time-varying acute exposures to zinc

The potential for delayed mortality following short-term episodic pollution events was evaluated by exposing cladocerans (Ceriodaphnia dubia) and rainbow trout (Oncorhynchus mykiss) to zinc (Zn) in various 1- to 48-h and 1- to 96-h exposures, respectively, followed by transferring the exposed organisms to clean water for up to 47 h for C. dubia and up to 95 h for trout for additional observation.
Authors
Christopher A. Mebane, Chris D. Ivey, Ning Wang, Jeffery Steevens, Danielle M. Cleveland, Michael C Elias, James R Justice, Kathryn Gallagher, Robert N. Brent

Assessing cyanobacterial frequency and abundance at surface waters near drinking water intakes across the United States

This study presents the first large-scale assessment of cyanobacterial frequency and abundance of surface water near drinking water intakes across the United States. Public water systems serve drinking water to nearly 90% of the United States population. Cyanobacteria and their toxins may degrade the quality of finished drinking water and can lead to negative health consequences. Satellite imagery
Authors
Megan Coffer, Blake A. Schaeffer, Katherine Foreman, Alex Porteous, Keith Loftin, Richard Stumpf, Jeremy Werdell, Erin Urquhart, Ryan Albert, John Darling

Is there an urban pesticide signature? Urban streams in five U.S. regions share common dissolved-phase pesticides but differ in predicted aquatic toxicity

Pesticides occur in urban streams globally, but the relation of occurrence to urbanization can be obscured by regional differences. In studies of five regions of the United States, we investigated the effect of region and urbanization on the occurrence and potential toxicity of dissolved pesticide mixtures. We analyzed 225 pesticide compounds in weekly discrete water samples collected during 6–12
Authors
Lisa H. Nowell, Patrick W. Moran, Laura M. Bexfield, Barbara Mahler, Peter C. Van Metre, Paul M. Bradley, Travis S. Schmidt, Daniel T. Button, Sharon L. Qi

Identification of Aphanomyces invadans, the cause of epizootic ulcerative syndrome, in smallmouth bass (Micropterus dolomieu) from the Cheat River, West Virginia, USA

The oomycete Aphanomyces invadans (Saprolegniales, Oomycetes), the cause of epizootic ulcerative syndrome (EUS), is an OIE (World Organization for Animal Health) reportable pathogen, capable of infecting many fish species worldwide in both freshwater and estuarine environments (Iberahim et al. 2018). Since the discovery of EUS in Japan in 1971 (Egusa and Masuda 1971), it has spread globally and ca
Authors
Heather L. Walsh, Vicki S. Blazer, Patricia M. Mazik

Untargeted lipidomics for determining cellular and sub-cellular responses in Zebrafish (Danio rerio) liver cells following exposure to complex mixtures in U.S. streams

Surface waters often contain a variety of chemical contaminants potentially capable of producing adverse outcomes in both humans and wildlife due to impacts from industrial, urban, and agricultural activity. Here, we report the results of a zebrafish liver (ZFL) cell-based lipidomics approach to assess the potential ecotoxicological effects of complex contaminant mixtures using water collected fro
Authors
Huajun Zhen, Quincy Teng, Jonathan D Mosley, Timothy W. Collette, Yang Yue, Paul M. Bradley, Drew R. Ekman

Perfluoroalkyl substances in plasma of smallmouth bass from the Chesapeake Bay Watershed

Smallmouth bass Micropterus dolomieu is an economically important sportfish and within the Chesapeake Bay watershed has experienced a high prevalence of external lesions, infectious disease, mortality events, reproductive endocrine disruption and population declines. To date, no clear or consistent associations with contaminants measured in fish tissue or surface water have been found. Therefore,
Authors
Vicki S. Blazer, Stephanie Gordon, Heather L. Walsh, Cheyenne R. Smith

Satellite remote sensing to assess cyanobacterial bloom frequency across the United States at multiple spatial scales

Cyanobacterial blooms can have negative effects on human health and local ecosystems. Field monitoring of cyanobacterial blooms can be costly, but satellite remote sensing has shown utility for more efficient spatial and temporal monitoring across the United States. Here, satellite imagery was used to assess the annual frequency of surface cyanobacterial blooms, defined for each satellite pixel as
Authors
Megan M. Coffer, Blake Schaeffer, Wilson B. Salls, Erin Urquhart, Keith Loftin, Richard P. Stumpf, P. Jeremy Werdell, John A. Darling

Arsenic in petroleum-contaminated groundwater near Bemidji, Minnesota is predicted to persist for centuries

We used a reactive transport model to investigate the cycling of geogenic arsenic (As) in a petroleum-contaminated aquifer. We simulated As mobilization and sequestration using surface complexation reactions with Fe(OH)3 during petroleum biodegradation coupled with Fe-reduction. Model results predict that dissolved As in the plume will exceed the U.S. and EU 10 µg/L drinking water standard for ~40

Authors
Brady A. Ziegler, G.-H. Crystal Ng, Isabelle M. Cozzarelli, Aubrey J. Dunshee, Madeline E. Schreiber

Identifying chemicals and mixtures of potential biological concern detected in passive samplers from Great Lakes tributaries using high-throughput data and biological pathways

Waterborne contaminants were monitored in 69 tributaries of the Laurentian Great Lakes in 2010 and 2014 using semipermeable membrane devices (SPMDs) and polar organic chemical integrative samplers (POCIS). A risk-based screening approach was used to prioritize chemicals and chemical mixtures, identify sites at greatest risk for biological impacts, and identify potential hazards to monitor at those
Authors
David Alvarez, Steven R. Corsi, Laura A. DeCicco, Daniel L. Villeneuve, Austin K. Baldwin

Pilot-scale expanded assessment of inorganic and organic tapwater exposures and predicted effects in Puerto Rico, USA

A pilot-scale expanded target assessment of mixtures of inorganic and organic contaminants in point-of-consumption drinking water (tapwater, TW) was conducted in Puerto Rico (PR) to continue to inform TW exposures and corresponding estimations of cumulative human-health risks across the US. In August 2018, a spatial synoptic pilot assessment of than 524 organic, 37 inorganic, and select microbiolo
Authors
Paul M. Bradley, Ingrid Y. Padilla, Kristin M. Romanok, Kelly Smalling, Michael J. Focazio, Sara E. Breitmeyer, Mary C. Cardon, Justin M. Conley, Nicola Evans, Carrie E Givens, James L. Gray, L. Earl Gray, Phillip C. Hartig, Michelle Hladik, Christopher P. Higgins, Luke R. Iwanowicz, Rachael F. Lane, Keith Loftin, R. Blaine McCleskey, Carrie A. McDonough, Elizabeth Medlock-Kakaley, Shannon M. Meppelink, Christopher P. Weis, Vickie S. Wilson

Cross-ecosystem fluxes of pesticides from prairie wetlands mediated by aquatic insect emergence: Implications for terrestrial insectivores

Contaminants alter the quantity and quality of insect prey available to terrestrial insectivores. In agricultural regions, the quantity of aquatic insects emerging from freshwaters can be impacted by insecticides originating from surrounding croplands. We hypothesized that, in such regions, adult aquatic insects could also act as vectors of pesticide transfer to terrestrial food webs. To estimate
Authors
Johanna M. Kraus, Kathryn Kuivila, Michelle Hladik, Neil Shook, David M. Mushet, Kelen Dowdy, Rachel Harrington

Trends in agricultural triazole fungicide sse in the United States, 1992–2016 and possible implications for antifungal-resistant fungi in human disease

Background:The fungus Aspergillus fumigatus (A. fumigatus) is the leading cause of invasive mold infections, which cause severe disease and death in immunocompromised people. Use of triazole antifungal medications in recent decades has improved patient survival; however, triazole-resistant infections have become common in parts of Europe and are emerging in the United States. Triazoles are also a
Authors
Mitsuru Toda, Karlyn D. Beer, Kathryn Kuivila, Tom M. Chiller, Brendan R. Jackson
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